fulvestrant-310 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the fulvestrant-310 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
AGBL5 ATP/GTP binding protein-like 5
AMT aminomethyltransferase
AQP3 aquaporin 3 (Gill blood group)
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARID4A AT rich interactive domain 4A (RBP1-like)
ARNT aryl hydrocarbon receptor nuclear translocator
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BTBD2 BTB (POZ) domain containing 2
BTN2A1 butyrophilin, subfamily 2, member A1
C19ORF66 chromosome 19 open reading frame 66
CACTIN cactin, spliceosome C complex subunit
CALU calumenin
CBX6 chromobox homolog 6
CCDC53 coiled-coil domain containing 53
CD19 CD19 molecule
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CHD3 chromodomain helicase DNA binding protein 3
CLCN7 chloride channel, voltage-sensitive 7
CORO1B coronin, actin binding protein, 1B
CTAGE9 CTAGE family, member 9
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DAAM1 dishevelled associated activator of morphogenesis 1
DDAH2 dimethylarginine dimethylaminohydrolase 2
DND1 DND microRNA-mediated repression inhibitor 1
DRP2 dystrophin related protein 2
EFNA1 ephrin-A1
EFNB3 ephrin-B3
ELF4 E74-like factor 4 (ets domain transcription factor)
EPS8L1 EPS8-like 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC3 exocyst complex component 3
FAM65A family with sequence similarity 65, member A
FKBP2 FK506 binding protein 2, 13kDa
FOXC1 forkhead box C1
FOXO1 forkhead box O1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GMEB1 glucocorticoid modulatory element binding protein 1
GPR3 G protein-coupled receptor 3
GSK3A glycogen synthase kinase 3 alpha
HAND1 heart and neural crest derivatives expressed 1
HIST1H3G histone cluster 1, H3g
HLA-E major histocompatibility complex, class I, E
HOXB7 homeobox B7
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
JOSD1 Josephin domain containing 1
KHK ketohexokinase (fructokinase)
KIF18A kinesin family member 18A
LMF2 lipase maturation factor 2
LSM12 LSM12 homolog (S. cerevisiae)
MAP2K2 mitogen-activated protein kinase kinase 2
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MPPE1 metallophosphoesterase 1
MT1HL1 metallothionein 1H-like 1
MVK mevalonate kinase
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
NELFE negative elongation factor complex member E
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PARVA parvin, alpha
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PLCD1 phospholipase C, delta 1
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PTGDS prostaglandin D2 synthase 21kDa (brain)
RNF220 ring finger protein 220
RPS11 ribosomal protein S11
RRAS related RAS viral (r-ras) oncogene homolog
RUNDC3A RUN domain containing 3A
SCAMP4 secretory carrier membrane protein 4
SEC24A SEC24 family member A
SERINC5 serine incorporator 5
SIL1 SIL1 nucleotide exchange factor
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SPN sialophorin
SQRDL sulfide quinone reductase-like (yeast)
STX5 syntaxin 5
TAOK3 TAO kinase 3
TBPL1 TBP-like 1
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast)
TJP2 tight junction protein 2
TLDC1 TBC/LysM-associated domain containing 1
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TPT1 tumor protein, translationally-controlled 1
TRAF2 TNF receptor-associated factor 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
VIPR1 vasoactive intestinal peptide receptor 1
WDR13 WD repeat domain 13
WWTR1 WW domain containing transcription regulator 1
ZBTB40 zinc finger and BTB domain containing 40
ZC3H7B zinc finger CCCH-type containing 7B
ZNF580 zinc finger protein 580

decreased expression

Symbol Name
ADGRA3 adhesion G protein-coupled receptor A3
AGRP agouti related neuropeptide
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ASB13 ankyrin repeat and SOCS box containing 13
BNC1 basonuclin 1
BNC2 basonuclin 2
BPHL biphenyl hydrolase-like (serine hydrolase)
C14ORF79 chromosome 14 open reading frame 79
C1ORF105 chromosome 1 open reading frame 105
C6 complement component 6
CAV3 caveolin 3
CCR4 chemokine (C-C motif) receptor 4
CD5 CD5 molecule
CD82 CD82 molecule
CD83 CD83 molecule
CLCA1 chloride channel accessory 1
CLCN6 chloride channel, voltage-sensitive 6
CLEC1A C-type lectin domain family 1, member A
CNTD2 cyclin N-terminal domain containing 2
CNTN1 contactin 1
CRYAA crystallin, alpha A
CTNNBIP1 catenin, beta interacting protein 1
CXCL9 chemokine (C-X-C motif) ligand 9
DCLRE1A DNA cross-link repair 1A
DHRS9 dehydrogenase/reductase (SDR family) member 9
DISC1 disrupted in schizophrenia 1
DMBT1 deleted in malignant brain tumors 1
DOK5 docking protein 5
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
DUSP13 dual specificity phosphatase 13
EGR3 early growth response 3
ELP6 elongator acetyltransferase complex subunit 6
EVX1 even-skipped homeobox 1
FAM153A family with sequence similarity 153, member A
FAM184A family with sequence similarity 184, member A
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FRAS1 Fraser extracellular matrix complex subunit 1
GAB2 GRB2-associated binding protein 2
GSTP1 glutathione S-transferase pi 1
HCG9 HLA complex group 9 (non-protein coding)
HDAC7 histone deacetylase 7
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
IL22 interleukin 22
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KRT1 keratin 1, type II
LCN2 lipocalin 2
LRRC20 leucine rich repeat containing 20
MAMLD1 mastermind-like domain containing 1
MAPK3 mitogen-activated protein kinase 3
MED31 mediator complex subunit 31
METTL2B methyltransferase like 2B
MLN motilin
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NCAPH non-SMC condensin I complex, subunit H
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NEUROD2 neuronal differentiation 2
NPY1R neuropeptide Y receptor Y1
NPY5R neuropeptide Y receptor Y5
ODF2 outer dense fiber of sperm tails 2
OLFML1 olfactomedin-like 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PAQR4 progestin and adipoQ receptor family member IV
PHOX2B paired-like homeobox 2b
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
POU3F3 POU class 3 homeobox 3
PQLC1 PQ loop repeat containing 1
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKCE protein kinase C, epsilon
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RBP1 retinol binding protein 1, cellular
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SAG S-antigen; retina and pineal gland (arrestin)
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2
SLC38A3 solute carrier family 38, member 3
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SPRR1B small proline-rich protein 1B
STAT5A signal transducer and activator of transcription 5A
SUSD4 sushi domain containing 4
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TGM5 transglutaminase 5
TSHB thyroid stimulating hormone, beta
TULP4 tubby like protein 4
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR3 WD repeat domain 3
WNT2 wingless-type MMTV integration site family member 2
WRN Werner syndrome, RecQ helicase-like
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZNF394 zinc finger protein 394
ZNF528 zinc finger protein 528