fulvestrant-367 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the fulvestrant-367 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAP1 ArfGAP with dual PH domains 1
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARFRP1 ADP-ribosylation factor related protein 1
ARHGAP19 Rho GTPase activating protein 19
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ASCL1 achaete-scute family bHLH transcription factor 1
ASTE1 asteroid homolog 1 (Drosophila)
ATF6 activating transcription factor 6
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
ATP13A2 ATPase type 13A2
B3GAT3 beta-1,3-glucuronyltransferase 3
C10ORF76 chromosome 10 open reading frame 76
C16ORF58 chromosome 16 open reading frame 58
C16ORF59 chromosome 16 open reading frame 59
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD6 CD6 molecule
CDKL3 cyclin-dependent kinase-like 3
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CIB2 calcium and integrin binding family member 2
CLTCL1 clathrin, heavy chain-like 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COL1A2 collagen, type I, alpha 2
COPZ2 coatomer protein complex, subunit zeta 2
CRYAB crystallin, alpha B
CST7 cystatin F (leukocystatin)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DUSP13 dual specificity phosphatase 13
EDNRA endothelin receptor type A
EMC1 ER membrane protein complex subunit 1
EPHA4 EPH receptor A4
EPOR erythropoietin receptor
FAM114A2 family with sequence similarity 114, member A2
FAM153A family with sequence similarity 153, member A
FASTK Fas-activated serine/threonine kinase
GAS7 growth arrest-specific 7
GK glycerol kinase
GMEB1 glucocorticoid modulatory element binding protein 1
GNRH2 gonadotropin-releasing hormone 2
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HNF4A hepatocyte nuclear factor 4, alpha
HSPA4 heat shock 70kDa protein 4
HSPB3 heat shock 27kDa protein 3
HUS1 HUS1 checkpoint homolog (S. pombe)
IL19 interleukin 19
IL1R1 interleukin 1 receptor, type I
IVL involucrin
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KCTD2 potassium channel tetramerization domain containing 2
KRTAP1-1 keratin associated protein 1-1
LHX6 LIM homeobox 6
LMTK1 lemur tail kinase 1
LUZP1 leucine zipper protein 1
MPPE1 metallophosphoesterase 1
MPV17 MpV17 mitochondrial inner membrane protein
MPZ myelin protein zero
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MT1HL1 metallothionein 1H-like 1
MTERF4 mitochondrial transcription termination factor 4
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXD4 MAX dimerization protein 4
NAGA N-acetylgalactosaminidase, alpha-
NCR1 natural cytotoxicity triggering receptor 1
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
NUP214 nucleoporin 214kDa
NUPL2 nucleoporin like 2
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
PARVA parvin, alpha
PCNX pecanex homolog (Drosophila)
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PQLC2 PQ loop repeat containing 2
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
RCAN1 regulator of calcineurin 1
RUNDC3A RUN domain containing 3A
SAG S-antigen; retina and pineal gland (arrestin)
SIDT2 SID1 transmembrane family, member 2
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC38A3 solute carrier family 38, member 3
SMA4 glucuronidase, beta pseudogene
SRY sex determining region Y
SZRD1 SUZ RNA binding domain containing 1
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TBC1D17 TBC1 domain family, member 17
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
TCP11 t-complex 11, testis-specific
THOC1 THO complex 1
TP53I11 tumor protein p53 inducible protein 11
TRAC T cell receptor alpha constant
TRADD TNFRSF1A-associated via death domain
TSPAN32 tetraspanin 32
TSSC4 tumor suppressing subtransferable candidate 4
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR13 WD repeat domain 13
YLPM1 YLP motif containing 1
ZKSCAN1 zinc finger with KRAB and SCAN domains 1
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ADORA3 adenosine A3 receptor
AP1AR adaptor-related protein complex 1 associated regulatory protein
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ASB7 ankyrin repeat and SOCS box containing 7
ATF7IP2 activating transcription factor 7 interacting protein 2
ATXN2 ataxin 2
BNC1 basonuclin 1
C12ORF29 chromosome 12 open reading frame 29
C1ORF109 chromosome 1 open reading frame 109
C1QTNF3 C1q and tumor necrosis factor related protein 3
CA5A carbonic anhydrase VA, mitochondrial
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CCDC170 coiled-coil domain containing 170
CCDC91 coiled-coil domain containing 91
CD2 CD2 molecule
CD207 CD207 molecule, langerin
CEMIP cell migration inducing protein, hyaluronan binding
CHRM2 cholinergic receptor, muscarinic 2
CPA3 carboxypeptidase A3 (mast cell)
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2
CTNNBIP1 catenin, beta interacting protein 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DIXDC1 DIX domain containing 1
ECE2 endothelin converting enzyme 2
EGR3 early growth response 3
EPN3 epsin 3
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FGFBP1 fibroblast growth factor binding protein 1
FLJ11710 uncharacterized protein FLJ11710
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GAL3ST4 galactose-3-O-sulfotransferase 4
GNAT3 guanine nucleotide binding protein, alpha transducing 3
GPHN gephyrin
GRAMD1B GRAM domain containing 1B
GRPR gastrin-releasing peptide receptor
H2AFY2 H2A histone family, member Y2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IL10RA interleukin 10 receptor, alpha
IQCG IQ motif containing G
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLHL28 kelch-like family member 28
LEFTY2 left-right determination factor 2
LGMN legumain
LIN28A lin-28 homolog A (C. elegans)
LOC257152 uncharacterized LOC257152
LOC441601 septin 7 pseudogene
MC5R melanocortin 5 receptor
MED31 mediator complex subunit 31
METTL16 methyltransferase like 16
MRPL41 mitochondrial ribosomal protein L41
MRPL44 mitochondrial ribosomal protein L44
MT4 metallothionein 4
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCS1 neuronal calcium sensor 1
NIP7 NIP7, nucleolar pre-rRNA processing protein
NPY1R neuropeptide Y receptor Y1
OR10H1 olfactory receptor, family 10, subfamily H, member 1
PAK1IP1 PAK1 interacting protein 1
PDZD7 PDZ domain containing 7
PDZK1 PDZ domain containing 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RCOR3 REST corepressor 3
RDH8 retinol dehydrogenase 8 (all-trans)
RNF39 ring finger protein 39
S100A1 S100 calcium binding protein A1
SDK2 sidekick cell adhesion molecule 2
SH2D2A SH2 domain containing 2A
SLC39A2 solute carrier family 39 (zinc transporter), member 2
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SP1 Sp1 transcription factor
SPP2 secreted phosphoprotein 2, 24kDa
STAT5A signal transducer and activator of transcription 5A
TAAR2 trace amine associated receptor 2
TAC3 tachykinin 3
TDRD1 tudor domain containing 1
TGFBR1 transforming growth factor, beta receptor 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMOD3 tropomodulin 3 (ubiquitous)
TMPRSS5 transmembrane protease, serine 5
UBE2W ubiquitin-conjugating enzyme E2W (putative)
WWP1 WW domain containing E3 ubiquitin protein ligase 1
ZBED2 zinc finger, BED-type containing 2
ZNF276 zinc finger protein 276
ZNF408 zinc finger protein 408