| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the fulvestrant-4429 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACSS3 | acyl-CoA synthetase short-chain family member 3 |
| ACTA1 | actin, alpha 1, skeletal muscle |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
| ALOX15B | arachidonate 15-lipoxygenase, type B |
| ANK2 | ankyrin 2, neuronal |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) |
| APCS | amyloid P component, serum |
| ARSA | arylsulfatase A |
| ARTN | artemin |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CABP1 | calcium binding protein 1 |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CHRNE | cholinergic receptor, nicotinic, epsilon (muscle) |
| CLCA1 | chloride channel accessory 1 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLSTN3 | calsyntenin 3 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CTTN | cortactin |
| CYB5A | cytochrome b5 type A (microsomal) |
| CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| EDN3 | endothelin 3 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EMILIN2 | elastin microfibril interfacer 2 |
| ENG | endoglin |
| EPHB1 | EPH receptor B1 |
| FAM135A | family with sequence similarity 135, member A |
| FBXO2 | F-box protein 2 |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FGF9 | fibroblast growth factor 9 |
| FOXN2 | forkhead box N2 |
| GSPT1 | G1 to S phase transition 1 |
| GTPBP1 | GTP binding protein 1 |
| HDAC6 | histone deacetylase 6 |
| HFE | hemochromatosis |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HPSE2 | heparanase 2 (inactive) |
| HSPG2 | heparan sulfate proteoglycan 2 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IGHMBP2 | immunoglobulin mu binding protein 2 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| JAG1 | jagged 1 |
| KALRN | kalirin, RhoGEF kinase |
| KCNIP1 | Kv channel interacting protein 1 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KSR1 | kinase suppressor of ras 1 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LOC157562 | uncharacterized LOC157562 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LRP2BP | LRP2 binding protein |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| MEF2D | myocyte enhancer factor 2D |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MST1 | macrophage stimulating 1 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| NDRG2 | NDRG family member 2 |
| NPTX2 | neuronal pentraxin II |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NRL | neural retina leucine zipper |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| OLFM1 | olfactomedin 1 |
| OR7E24 | olfactory receptor, family 7, subfamily E, member 24 |
| PADI2 | peptidyl arginine deiminase, type II |
| PCDHGB6 | protocadherin gamma subfamily B, 6 |
| PDPN | podoplanin |
| PGK2 | phosphoglycerate kinase 2 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLK3 | polo-like kinase 3 |
| PNPLA3 | patatin-like phospholipase domain containing 3 |
| PODNL1 | podocan-like 1 |
| PTAFR | platelet-activating factor receptor |
| RAB33A | RAB33A, member RAS oncogene family |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RUNX1 | runt-related transcription factor 1 |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SOX21 | SRY (sex determining region Y)-box 21 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TEF | thyrotrophic embryonic factor |
| THSD4 | thrombospondin, type I, domain containing 4 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TPM3 | tropomyosin 3 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TTC38 | tetratricopeptide repeat domain 38 |
| VHL | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
| WDR1 | WD repeat domain 1 |
| WNT6 | wingless-type MMTV integration site family, member 6 |
| ZFP2 | ZFP2 zinc finger protein |
| ZKSCAN8 | zinc finger with KRAB and SCAN domains 8 |
| ZNF334 | zinc finger protein 334 |
| Symbol | Name |
|---|---|
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| ALPK1 | alpha-kinase 1 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BMPR1B | bone morphogenetic protein receptor, type IB |
| BTC | betacellulin |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C1S | complement component 1, s subcomponent |
| CA8 | carbonic anhydrase VIII |
| CCDC186 | coiled-coil domain containing 186 |
| CHM | choroideremia (Rab escort protein 1) |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYB5R2 | cytochrome b5 reductase 2 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DEPDC5 | DEP domain containing 5 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DUSP8 | dual specificity phosphatase 8 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FANCC | Fanconi anemia, complementation group C |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4C | histone cluster 1, H4c |
| HIST1H4D | histone cluster 1, H4d |
| HOXA4 | homeobox A4 |
| HOXA6 | homeobox A6 |
| HOXC4 | homeobox C4 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LINS | lines homolog (Drosophila) |
| LRRC37A4P | leucine rich repeat containing 37, member A4, pseudogene |
| LRRC6 | leucine rich repeat containing 6 |
| MANBA | mannosidase, beta A, lysosomal |
| MED18 | mediator complex subunit 18 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MICALL2 | MICAL-like 2 |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MMP13 | matrix metallopeptidase 13 |
| MTA2 | metastasis associated 1 family, member 2 |
| MX1 | MX dynamin-like GTPase 1 |
| NOTCH1 | notch 1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OLFML2B | olfactomedin-like 2B |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PCBP4 | poly(rC) binding protein 4 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLXNA3 | plexin A3 |
| PODXL2 | podocalyxin-like 2 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRSS22 | protease, serine, 22 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| QSER1 | glutamine and serine rich 1 |
| RNF122 | ring finger protein 122 |
| SCG5 | secretogranin V |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SKIL | SKI-like proto-oncogene |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SPIDR | scaffolding protein involved in DNA repair |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYNPO | synaptopodin |
| SYT17 | synaptotagmin XVII |
| TAOK1 | TAO kinase 1 |
| TEP1 | telomerase-associated protein 1 |
| THRB | thyroid hormone receptor, beta |
| TLR1 | toll-like receptor 1 |
| TLR2 | toll-like receptor 2 |
| TMEM180 | transmembrane protein 180 |
| TMEM53 | transmembrane protein 53 |
| TUBA3C | tubulin, alpha 3c |
| UBQLN4 | ubiquilin 4 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VN1R1 | vomeronasal 1 receptor 1 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZNF358 | zinc finger protein 358 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF652 | zinc finger protein 652 |
| ZNF702P | zinc finger protein 702, pseudogene |
| ZNF816 | zinc finger protein 816 |
| ZNF862 | zinc finger protein 862 |
