| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the fulvestrant-4462 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCK2 | aarF domain containing kinase 2 |
| ADD2 | adducin 2 (beta) |
| ADRA1D | adrenoceptor alpha 1D |
| AKAP4 | A kinase (PRKA) anchor protein 4 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALMS1 | Alstrom syndrome protein 1 |
| APC2 | adenomatosis polyposis coli 2 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCDC132 | coiled-coil domain containing 132 |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CD300C | CD300c molecule |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CXXC4 | CXXC finger protein 4 |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| DACH1 | dachshund family transcription factor 1 |
| DKFZP434L187 | uncharacterized LOC26082 |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 |
| EPHA5 | EPH receptor A5 |
| EPS8L1 | EPS8-like 1 |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| ERGIC3 | ERGIC and golgi 3 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| EXOC6B | exocyst complex component 6B |
| FGB | fibrinogen beta chain |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FLT1 | fms-related tyrosine kinase 1 |
| FRZB | frizzled-related protein |
| GAB1 | GRB2-associated binding protein 1 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GADD45GIP1 | growth arrest and DNA-damage-inducible, gamma interacting protein 1 |
| GAP43 | growth associated protein 43 |
| GATA3 | GATA binding protein 3 |
| GPLD1 | glycosylphosphatidylinositol specific phospholipase D1 |
| HAO2 | hydroxyacid oxidase 2 (long chain) |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HIST1H4F | histone cluster 1, H4f |
| HOXB3 | homeobox B3 |
| INHBA | inhibin, beta A |
| IRF4 | interferon regulatory factor 4 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| KIF1A | kinesin family member 1A |
| KRT19P2 | keratin 19 pseudogene 2 |
| LEPR | leptin receptor |
| LINC00312 | long intergenic non-protein coding RNA 312 |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| MED25 | mediator complex subunit 25 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MMP3 | matrix metallopeptidase 3 |
| MTRF1L | mitochondrial translational release factor 1-like |
| NPTX1 | neuronal pentraxin I |
| NPTX2 | neuronal pentraxin II |
| NPY2R | neuropeptide Y receptor Y2 |
| PALM | paralemmin |
| PCSK2 | proprotein convertase subtilisin/kexin type 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PIGR | polymeric immunoglobulin receptor |
| PKP4 | plakophilin 4 |
| PLK3 | polo-like kinase 3 |
| PLXNA2 | plexin A2 |
| PODNL1 | podocan-like 1 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PRDX2 | peroxiredoxin 2 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PRKG1 | protein kinase, cGMP-dependent, type I |
| PTCH1 | patched 1 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PTN | pleiotrophin |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SLC45A2 | solute carrier family 45, member 2 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPAG8 | sperm associated antigen 8 |
| SPATA1 | spermatogenesis associated 1 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) |
| TCN2 | transcobalamin II |
| TPM3 | tropomyosin 3 |
| TRIM14 | tripartite motif containing 14 |
| TRIM33 | tripartite motif containing 33 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| WDR78 | WD repeat domain 78 |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| AURKC | aurora kinase C |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BMP4 | bone morphogenetic protein 4 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNO | cyclin O |
| CDK9 | cyclin-dependent kinase 9 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CFAP45 | cilia and flagella associated protein 45 |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNTN1 | contactin 1 |
| CNTNAP1 | contactin associated protein 1 |
| COL9A3 | collagen, type IX, alpha 3 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DDN | dendrin |
| DNAL4 | dynein, axonemal, light chain 4 |
| DNM1 | dynamin 1 |
| EDC4 | enhancer of mRNA decapping 4 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FRMD1 | FERM domain containing 1 |
| FZD8 | frizzled class receptor 8 |
| GAS2 | growth arrest-specific 2 |
| GAS8 | growth arrest-specific 8 |
| GPR39 | G protein-coupled receptor 39 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H4D | histone cluster 1, H4d |
| HOXA6 | homeobox A6 |
| HOXB9 | homeobox B9 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KIAA0319L | KIAA0319-like |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MON1B | MON1 secretory trafficking family member B |
| MT1M | metallothionein 1M |
| MTCP1 | mature T-cell proliferation 1 |
| MX1 | MX dynamin-like GTPase 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| P3H2 | prolyl 3-hydroxylase 2 |
| PENK | proenkephalin |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PHGDH | phosphoglycerate dehydrogenase |
| PKN1 | protein kinase N1 |
| PLD3 | phospholipase D family, member 3 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLSCR2 | phospholipid scramblase 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PQLC2 | PQ loop repeat containing 2 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RNF43 | ring finger protein 43 |
| RPGRIP1L | RPGRIP1-like |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SETD1A | SET domain containing 1A |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SIRT2 | sirtuin 2 |
| SLC35F6 | solute carrier family 35, member F6 |
| SMO | smoothened, frizzled class receptor |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| STK16 | serine/threonine kinase 16 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| THRB | thyroid hormone receptor, beta |
| TLR1 | toll-like receptor 1 |
| TRABD | TraB domain containing |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TUBA3C | tubulin, alpha 3c |
| UBXN6 | UBX domain protein 6 |
| USP18 | ubiquitin specific peptidase 18 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XPC | xeroderma pigmentosum, complementation group C |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF358 | zinc finger protein 358 |
| ZNF528 | zinc finger protein 528 |
| ZNF573 | zinc finger protein 573 |
| ZNF639 | zinc finger protein 639 |
| ZNF711 | zinc finger protein 711 |
| ZNF74 | zinc finger protein 74 |
| ZNF76 | zinc finger protein 76 |
