| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the fulvestrant-5202 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ACTN2 | actinin, alpha 2 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ADM | adrenomedullin |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| BTG2 | BTG family, member 2 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CALD1 | caldesmon 1 |
| CCDC181 | coiled-coil domain containing 181 |
| CCNG2 | cyclin G2 |
| CDK6 | cyclin-dependent kinase 6 |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EXOC7 | exocyst complex component 7 |
| FAM110B | family with sequence similarity 110, member B |
| FAM214B | family with sequence similarity 214, member B |
| FBN2 | fibrillin 2 |
| FGL1 | fibrinogen-like 1 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR157 | G protein-coupled receptor 157 |
| GRB7 | growth factor receptor-bound protein 7 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRM1 | glutamate receptor, metabotropic 1 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HFE | hemochromatosis |
| HLA-C | major histocompatibility complex, class I, C |
| HYAL3 | hyaluronoglucosaminidase 3 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IGKV4-1 | immunoglobulin kappa variable 4-1 |
| IL1R1 | interleukin 1 receptor, type I |
| KLHL25 | kelch-like family member 25 |
| KRT38 | keratin 38, type I |
| LAMB4 | laminin, beta 4 |
| LBP | lipopolysaccharide binding protein |
| LIN7A | lin-7 homolog A (C. elegans) |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| METTL7A | methyltransferase like 7A |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MID1 | midline 1 |
| MNMIP1 | manchette microtubule inner protein 1 |
| MTMR8 | myotubularin related protein 8 |
| MX1 | MX dynamin-like GTPase 1 |
| MXD4 | MAX dimerization protein 4 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NLRX1 | NLR family member X1 |
| NMT1 | N-myristoyltransferase 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NTM | neurotrimin |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PHF1 | PHD finger protein 1 |
| PIDD1 | p53-induced death domain protein 1 |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PLD2 | phospholipase D2 |
| PLLP | plasmolipin |
| PMEL | premelanosome protein |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PSCA | prostate stem cell antigen |
| PTHLH | parathyroid hormone-like hormone |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RPA4 | replication protein A4, 30kDa |
| RRBP1 | ribosome binding protein 1 |
| RUNX1 | runt-related transcription factor 1 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SDC3 | syndecan 3 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERHL2 | serine hydrolase-like 2 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SNX13 | sorting nexin 13 |
| SPRR1B | small proline-rich protein 1B |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| STON1 | stonin 1 |
| TBC1D2 | TBC1 domain family, member 2 |
| TLE2 | transducin-like enhancer of split 2 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TUBA3C | tubulin, alpha 3c |
| VAMP5 | vesicle-associated membrane protein 5 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF226 | zinc finger protein 226 |
| ZNF804A | zinc finger protein 804A |
| ZNF821 | zinc finger protein 821 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACTL8 | actin-like 8 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| AMD1 | adenosylmethionine decarboxylase 1 |
| B3GALNT1 | beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BBS7 | Bardet-Biedl syndrome 7 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC121 | coiled-coil domain containing 121 |
| CCDC47 | coiled-coil domain containing 47 |
| CCND1 | cyclin D1 |
| CEP85 | centrosomal protein 85kDa |
| CHKB | choline kinase beta |
| CHML | choroideremia-like (Rab escort protein 2) |
| CISH | cytokine inducible SH2-containing protein |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| COMMD10 | COMM domain containing 10 |
| CTPS1 | CTP synthase 1 |
| CUEDC1 | CUE domain containing 1 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| EGR3 | early growth response 3 |
| EVPL | envoplakin |
| EXOC5 | exocyst complex component 5 |
| FAM155B | family with sequence similarity 155, member B |
| FBRS | fibrosin |
| FHL2 | four and a half LIM domains 2 |
| FOXC1 | forkhead box C1 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| HDAC4 | histone deacetylase 4 |
| HSPB8 | heat shock 22kDa protein 8 |
| IER3 | immediate early response 3 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| KAT2A | K(lysine) acetyltransferase 2A |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIAA0125 | KIAA0125 |
| KIF16B | kinesin family member 16B |
| KLF10 | Kruppel-like factor 10 |
| KLHL21 | kelch-like family member 21 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LMAN1 | lectin, mannose-binding, 1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MICB | MHC class I polypeptide-related sequence B |
| MPPED2 | metallophosphoesterase domain containing 2 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| MYO1E | myosin IE |
| NKRF | NFKB repressing factor |
| NMRK1 | nicotinamide riboside kinase 1 |
| NPY1R | neuropeptide Y receptor Y1 |
| OSMR | oncostatin M receptor |
| PARG | poly (ADP-ribose) glycohydrolase |
| PC | pyruvate carboxylase |
| PCDHA6 | protocadherin alpha 6 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDZK1 | PDZ domain containing 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PODXL | podocalyxin-like |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SACS | sacsin molecular chaperone |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SDCCAG3 | serologically defined colon cancer antigen 3 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 |
| SIRT6 | sirtuin 6 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SMAD7 | SMAD family member 7 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPHK1 | sphingosine kinase 1 |
| STC2 | stanniocalcin 2 |
| SULF1 | sulfatase 1 |
| SYBU | syntabulin (syntaxin-interacting) |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMPRSS3 | transmembrane protease, serine 3 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| WDR3 | WD repeat domain 3 |
| XK | X-linked Kx blood group |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| ZCCHC2 | zinc finger, CCHC domain containing 2 |
| ZNF227 | zinc finger protein 227 |
| ZNF770 | zinc finger protein 770 |