| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the fulvestrant-523 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GNT | alpha-1,4-N-acetylglucosaminyltransferase |
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ACSL6 | acyl-CoA synthetase long-chain family member 6 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AEN | apoptosis enhancing nuclease |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AGTR2 | angiotensin II receptor, type 2 |
| AKIP1 | A kinase (PRKA) interacting protein 1 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ARMC4 | armadillo repeat containing 4 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ARRB2 | arrestin, beta 2 |
| ASIP | agouti signaling protein |
| ATG12 | autophagy related 12 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| BIN1 | bridging integrator 1 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C6 | complement component 6 |
| CAMK1G | calcium/calmodulin-dependent protein kinase IG |
| CASR | calcium-sensing receptor |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CD82 | CD82 molecule |
| CFAP70 | cilia and flagella associated protein 70 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CLEC1A | C-type lectin domain family 1, member A |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| CRYAB | crystallin, alpha B |
| CTTN | cortactin |
| CYLC1 | cylicin, basic protein of sperm head cytoskeleton 1 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DISC1 | disrupted in schizophrenia 1 |
| DPY19L1 | dpy-19-like 1 (C. elegans) |
| ELAVL4 | ELAV like neuron-specific RNA binding protein 4 |
| EML2 | echinoderm microtubule associated protein like 2 |
| EPS8L3 | EPS8-like 3 |
| EXPH5 | exophilin 5 |
| FAM107A | family with sequence similarity 107, member A |
| FECH | ferrochelatase |
| FOXO1 | forkhead box O1 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| FXYD7 | FXYD domain containing ion transport regulator 7 |
| GLRA2 | glycine receptor, alpha 2 |
| GLS | glutaminase |
| GMPPB | GDP-mannose pyrophosphorylase B |
| GNRH2 | gonadotropin-releasing hormone 2 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| H2AFY2 | H2A histone family, member Y2 |
| HNF1B | HNF1 homeobox B |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| HTT | huntingtin |
| KCNJ10 | potassium channel, inwardly rectifying subfamily J, member 10 |
| KIFAP3 | kinesin-associated protein 3 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| KIR3DL1 | killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 |
| L1CAM | L1 cell adhesion molecule |
| LECT1 | leukocyte cell derived chemotaxin 1 |
| LENEP | lens epithelial protein |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MED18 | mediator complex subunit 18 |
| MINK1 | misshapen-like kinase 1 |
| MT1HL1 | metallothionein 1H-like 1 |
| MVK | mevalonate kinase |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow |
| MYT1 | myelin transcription factor 1 |
| NDRG2 | NDRG family member 2 |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa |
| NUP214 | nucleoporin 214kDa |
| OLFM1 | olfactomedin 1 |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PIGV | phosphatidylinositol glycan anchor biosynthesis, class V |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RHOH | ras homolog family member H |
| RPS16 | ribosomal protein S16 |
| RUNDC3A | RUN domain containing 3A |
| S100A4 | S100 calcium binding protein A4 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCARB2 | scavenger receptor class B, member 2 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMAD3 | SMAD family member 3 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SP110 | SP110 nuclear body protein |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| TMEM242 | transmembrane protein 242 |
| TMEM53 | transmembrane protein 53 |
| TMF1 | TATA element modulatory factor 1 |
| TSC22D3 | TSC22 domain family, member 3 |
| TUBA3C | tubulin, alpha 3c |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| VWA1 | von Willebrand factor A domain containing 1 |
| YIPF4 | Yip1 domain family, member 4 |
| ZNF576 | zinc finger protein 576 |
| Symbol | Name |
|---|---|
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AIDA | axin interactor, dorsalization associated |
| ALPK1 | alpha-kinase 1 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BCL7B | B-cell CLL/lymphoma 7B |
| BIN3 | bridging integrator 3 |
| C12ORF29 | chromosome 12 open reading frame 29 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CA11 | carbonic anhydrase XI |
| CCDC176 | coiled-coil domain containing 176 |
| CHEK2 | checkpoint kinase 2 |
| CLDN15 | claudin 15 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CTF1 | cardiotrophin 1 |
| CUL9 | cullin 9 |
| DCP1A | decapping mRNA 1A |
| DENND1B | DENN/MADD domain containing 1B |
| DENND4B | DENN/MADD domain containing 4B |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DMXL1 | Dmx-like 1 |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| DUSP2 | dual specificity phosphatase 2 |
| E4F1 | E4F transcription factor 1 |
| EDC4 | enhancer of mRNA decapping 4 |
| EFNA3 | ephrin-A3 |
| EGR3 | early growth response 3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 |
| EPX | eosinophil peroxidase |
| ERCC4 | excision repair cross-complementation group 4 |
| FAM188A | family with sequence similarity 188, member A |
| FAM192A | family with sequence similarity 192, member A |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 |
| FJX1 | four jointed box 1 (Drosophila) |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| GAB2 | GRB2-associated binding protein 2 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| GMIP | GEM interacting protein |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HIRA | histone cell cycle regulator |
| HIRIP3 | HIRA interacting protein 3 |
| IFNA14 | interferon, alpha 14 |
| IL17RA | interleukin 17 receptor A |
| IL7R | interleukin 7 receptor |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| JMJD4 | jumonji domain containing 4 |
| JOSD1 | Josephin domain containing 1 |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KLK8 | kallikrein-related peptidase 8 |
| LMTK1 | lemur tail kinase 1 |
| LONP1 | lon peptidase 1, mitochondrial |
| LUC7L | LUC7-like (S. cerevisiae) |
| LUZP4 | leucine zipper protein 4 |
| MALL | mal, T-cell differentiation protein-like |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MLXIPL | MLX interacting protein-like |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
| NPY1R | neuropeptide Y receptor Y1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NUP93 | nucleoporin 93kDa |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PAX9 | paired box 9 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| POMGNT1 | protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PRKCE | protein kinase C, epsilon |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RDH5 | retinol dehydrogenase 5 (11-cis/9-cis) |
| RECQL4 | RecQ protein-like 4 |
| S100A2 | S100 calcium binding protein A2 |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TP53BP1 | tumor protein p53 binding protein 1 |
| TRAF2 | TNF receptor-associated factor 2 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| USP20 | ubiquitin specific peptidase 20 |
| USP39 | ubiquitin specific peptidase 39 |
| WDR18 | WD repeat domain 18 |
| WDR44 | WD repeat domain 44 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 |
| ZNF668 | zinc finger protein 668 |