fulvestrant-5565 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the fulvestrant-5565 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY2 adenylate cyclase 2 (brain)
AEBP1 AE binding protein 1
AMPD3 adenosine monophosphate deaminase 3
AQP3 aquaporin 3 (Gill blood group)
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ATAT1 alpha tubulin acetyltransferase 1
ATP10B ATPase, class V, type 10B
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCDC64 coiled-coil domain containing 64
CCDC87 coiled-coil domain containing 87
CCL23 chemokine (C-C motif) ligand 23
CCNG2 cyclin G2
CCR7 chemokine (C-C motif) receptor 7
CDKN2A cyclin-dependent kinase inhibitor 2A
CFAP69 cilia and flagella associated protein 69
CLEC4E C-type lectin domain family 4, member E
CNTD2 cyclin N-terminal domain containing 2
COL9A3 collagen, type IX, alpha 3
CRISP2 cysteine-rich secretory protein 2
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DIAPH2-AS1 DIAPH2 antisense RNA 1
DMPK dystrophia myotonica-protein kinase
DPF1 D4, zinc and double PHD fingers family 1
DPF3 D4, zinc and double PHD fingers, family 3
DRD1 dopamine receptor D1
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EPX eosinophil peroxidase
FAM46C family with sequence similarity 46, member C
FBXO21 F-box protein 21
FGB fibrinogen beta chain
FGF22 fibroblast growth factor 22
FLJ11292
FSCN1 fascin actin-bundling protein 1
GCKR glucokinase (hexokinase 4) regulator
GIMAP6 GTPase, IMAP family member 6
GJA4 gap junction protein, alpha 4, 37kDa
GNAS GNAS complex locus
HOXA11 homeobox A11
HYAL3 hyaluronoglucosaminidase 3
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFFO1 intermediate filament family orphan 1
IFT27 intraflagellar transport 27
IL22 interleukin 22
KIF13B kinesin family member 13B
LEPR leptin receptor
LONRF3 LON peptidase N-terminal domain and ring finger 3
MAOA monoamine oxidase A
MAPK10 mitogen-activated protein kinase 10
MFGE8 milk fat globule-EGF factor 8 protein
MLN motilin
MOBP myelin-associated oligodendrocyte basic protein
MR1 major histocompatibility complex, class I-related
OR7A10 olfactory receptor, family 7, subfamily A, member 10
PCDH9 protocadherin 9
PML promyelocytic leukemia
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PRDX2 peroxiredoxin 2
PRKCQ protein kinase C, theta
PSAT1 phosphoserine aminotransferase 1
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTX3 pentraxin 3, long
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGS4 regulator of G-protein signaling 4
RPL35A ribosomal protein L35a
RUNX1 runt-related transcription factor 1
RYR1 ryanodine receptor 1 (skeletal)
SIPA1L3 signal-induced proliferation-associated 1 like 3
SOGA1 suppressor of glucose, autophagy associated 1
STON1 stonin 1
TAPT1 transmembrane anterior posterior transformation 1
TBX3 T-box 3
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRBC1 T cell receptor beta constant 1
TRIM22 tripartite motif containing 22
TRIM3 tripartite motif containing 3
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TUBA3C tubulin, alpha 3c
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
VIPR1 vasoactive intestinal peptide receptor 1
WAS Wiskott-Aldrich syndrome
WNT8B wingless-type MMTV integration site family, member 8B
ZDHHC8P1 zinc finger, DHHC-type containing 8 pseudogene 1
ZMAT4 zinc finger, matrin-type 4
ZNF362 zinc finger protein 362

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACBD4 acyl-CoA binding domain containing 4
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ARPIN actin-related protein 2/3 complex inhibitor
ARTN artemin
ASPHD1 aspartate beta-hydroxylase domain containing 1
AXIN1 axin 1
BCAS1 breast carcinoma amplified sequence 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BHLHE41 basic helix-loop-helix family, member e41
C10ORF2 chromosome 10 open reading frame 2
C1ORF159 chromosome 1 open reading frame 159
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C5AR2 complement component 5a receptor 2
CCND1 cyclin D1
CFD complement factor D (adipsin)
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CST6 cystatin E/M
CUZD1 CUB and zona pellucida-like domains 1
CXCL12 chemokine (C-X-C motif) ligand 12
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DPH2 DPH2 homolog (S. cerevisiae)
EGR3 early growth response 3
FAM155B family with sequence similarity 155, member B
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FHL2 four and a half LIM domains 2
FLJ11710 uncharacterized protein FLJ11710
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAN gigaxonin
GATA4 GATA binding protein 4
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJA1 gap junction protein, alpha 1, 43kDa
GMPR guanosine monophosphate reductase
HIST1H2AI histone cluster 1, H2ai
HSPB8 heat shock 22kDa protein 8
ICK intestinal cell (MAK-like) kinase
IER3 immediate early response 3
IQCC IQ motif containing C
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIAA0125 KIAA0125
LAMA3 laminin, alpha 3
LOXL3 lysyl oxidase-like 3
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRP3 low density lipoprotein receptor-related protein 3
LRP5L low density lipoprotein receptor-related protein 5-like
MAST3 microtubule associated serine/threonine kinase 3
MDM4 MDM4, p53 regulator
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MPPED2 metallophosphoesterase domain containing 2
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NPY1R neuropeptide Y receptor Y1
NPY5R neuropeptide Y receptor Y5
PCOLCE2 procollagen C-endopeptidase enhancer 2
PDZK1 PDZ domain containing 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
POLH polymerase (DNA directed), eta
POMT2 protein-O-mannosyltransferase 2
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
R3HCC1L R3H domain and coiled-coil containing 1-like
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RCL1 RNA terminal phosphate cyclase-like 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SAMD9 sterile alpha motif domain containing 9
SCN1B sodium channel, voltage gated, type I beta subunit
SENP7 SUMO1/sentrin specific peptidase 7
SGK1 serum/glucocorticoid regulated kinase 1
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SMAD7 SMAD family member 7
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
STARD13 StAR-related lipid transfer (START) domain containing 13
STC2 stanniocalcin 2
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYBU syntabulin (syntaxin-interacting)
TGFBR1 transforming growth factor, beta receptor 1
THOP1 thimet oligopeptidase 1
TMEM120B transmembrane protein 120B
TMEM121 transmembrane protein 121
TMEM209 transmembrane protein 209
TMEM242 transmembrane protein 242
TMPRSS3 transmembrane protease, serine 3
TRIM25 tripartite motif containing 25
TSKU tsukushi, small leucine rich proteoglycan
TWISTNB TWIST neighbor
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF324 zinc finger protein 324
ZNF34 zinc finger protein 34
ZNF442 zinc finger protein 442
ZNF573 zinc finger protein 573
ZNF675 zinc finger protein 675