| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the fulvestrant-5598 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABO | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALDOAP2 | aldolase A, fructose-bisphosphate pseudogene 2 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 |
| BDKRB2 | bradykinin receptor B2 |
| BLNK | B-cell linker |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CA4 | carbonic anhydrase IV |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CASQ2 | calsequestrin 2 (cardiac muscle) |
| CD7 | CD7 molecule |
| COL3A1 | collagen, type III, alpha 1 |
| CRP | C-reactive protein, pentraxin-related |
| CRYGD | crystallin, gamma D |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) |
| CTAG2 | cancer/testis antigen 2 |
| CTIF | CBP80/20-dependent translation initiation factor |
| CXORF21 | chromosome X open reading frame 21 |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DAPK1 | death-associated protein kinase 1 |
| DMPK | dystrophia myotonica-protein kinase |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| DYSF | dysferlin |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| EML2 | echinoderm microtubule associated protein like 2 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| EXOC6B | exocyst complex component 6B |
| FAT4 | FAT atypical cadherin 4 |
| FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 |
| FPR2 | formyl peptide receptor 2 |
| FSCN1 | fascin actin-bundling protein 1 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GGT1 | gamma-glutamyltransferase 1 |
| GIPC2 | GIPC PDZ domain containing family, member 2 |
| GRM4 | glutamate receptor, metabotropic 4 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HFE | hemochromatosis |
| HHAT | hedgehog acyltransferase |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HRASLS2 | HRAS-like suppressor 2 |
| HSD3B2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IGHD | immunoglobulin heavy constant delta |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IL1B | interleukin 1, beta |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IZUMO4 | IZUMO family member 4 |
| KIF25 | kinesin family member 25 |
| KIF26B | kinesin family member 26B |
| KLK7 | kallikrein-related peptidase 7 |
| KRT14 | keratin 14, type I |
| KRT9 | keratin 9, type I |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MED25 | mediator complex subunit 25 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MXD4 | MAX dimerization protein 4 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NME8 | NME/NM23 family member 8 |
| NOTCH4 | notch 4 |
| NPHP4 | nephronophthisis 4 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| POU3F2 | POU class 3 homeobox 2 |
| PQBP1 | polyglutamine binding protein 1 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRKCE | protein kinase C, epsilon |
| PTCRA | pre T-cell antigen receptor alpha |
| PVR | poliovirus receptor |
| RABEP2 | rabaptin, RAB GTPase binding effector protein 2 |
| RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1 |
| RAP2B | RAP2B, member of RAS oncogene family |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RGCC | regulator of cell cycle |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RUNX1 | runt-related transcription factor 1 |
| S100A2 | S100 calcium binding protein A2 |
| S100A7 | S100 calcium binding protein A7 |
| SNPH | syntaphilin |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| STON1 | stonin 1 |
| TAPBP | TAP binding protein (tapasin) |
| TCF20 | transcription factor 20 (AR1) |
| TCP10L | t-complex 10-like |
| TLR2 | toll-like receptor 2 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TRO | trophinin |
| TRPC3 | transient receptor potential cation channel, subfamily C, member 3 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AEN | apoptosis enhancing nuclease |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ARTN | artemin |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| CCND1 | cyclin D1 |
| CDK20 | cyclin-dependent kinase 20 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CTC1 | CTS telomere maintenance complex component 1 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| DCP1A | decapping mRNA 1A |
| DVL1 | dishevelled segment polarity protein 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| ECE1 | endothelin converting enzyme 1 |
| EGR3 | early growth response 3 |
| ERCC5 | excision repair cross-complementation group 5 |
| FAM204A | family with sequence similarity 204, member A |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOXC1 | forkhead box C1 |
| FOXN2 | forkhead box N2 |
| FRMD1 | FERM domain containing 1 |
| GATA4 | GATA binding protein 4 |
| GID4 | GID complex subunit 4 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| HDAC11 | histone deacetylase 11 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HOXA4 | homeobox A4 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HSPB8 | heat shock 22kDa protein 8 |
| HYI | hydroxypyruvate isomerase (putative) |
| IER3 | immediate early response 3 |
| IFT54 | intraflagellar transport 54 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IL4R | interleukin 4 receptor |
| IRF1 | interferon regulatory factor 1 |
| JADE1 | jade family PHD finger 1 |
| JAK2 | Janus kinase 2 |
| KIAA0125 | KIAA0125 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRRC61 | leucine rich repeat containing 61 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAGEF1 | melanoma antigen family F1 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MVD | mevalonate (diphospho) decarboxylase |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NPY1R | neuropeptide Y receptor Y1 |
| NTF3 | neurotrophin 3 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDZK1 | PDZ domain containing 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PRF1 | perforin 1 (pore forming protein) |
| PRR3 | proline rich 3 |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| PUS1 | pseudouridylate synthase 1 |
| RAB3A | RAB3A, member RAS oncogene family |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RP2 | retinitis pigmentosa 2 (X-linked recessive) |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRAGB | Ras-related GTP binding B |
| SAMD9 | sterile alpha motif domain containing 9 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMAD7 | SMAD family member 7 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STC2 | stanniocalcin 2 |
| SYBU | syntabulin (syntaxin-interacting) |
| TBC1D17 | TBC1 domain family, member 17 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TLR5 | toll-like receptor 5 |
| TMEM120B | transmembrane protein 120B |
| TMPRSS3 | transmembrane protease, serine 3 |
| TRAF2 | TNF receptor-associated factor 2 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| WDR3 | WD repeat domain 3 |
| WLS | wntless Wnt ligand secretion mediator |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZNF442 | zinc finger protein 442 |
| ZNF696 | zinc finger protein 696 |
| ZNF816 | zinc finger protein 816 |
