| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the fulvestrant-5964 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ADAM8 | ADAM metallopeptidase domain 8 |
| ADGRD2 | adhesion G protein-coupled receptor D2 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AREG | amphiregulin |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| BMP1 | bone morphogenetic protein 1 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| CALCR | calcitonin receptor |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CD52 | CD52 molecule |
| CD58 | CD58 molecule |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| COL10A1 | collagen, type X, alpha 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 |
| CYTH4 | cytohesin 4 |
| DBP | D site of albumin promoter (albumin D-box) binding protein |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FGF22 | fibroblast growth factor 22 |
| FRMD4B | FERM domain containing 4B |
| GH1 | growth hormone 1 |
| GMPR | guanosine monophosphate reductase |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPC1 | glypican 1 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPM6B | glycoprotein M6B |
| HES2 | hes family bHLH transcription factor 2 |
| HFE | hemochromatosis |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H4D | histone cluster 1, H4d |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| ING1 | inhibitor of growth family, member 1 |
| KIR2DL2 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 |
| KLHL35 | kelch-like family member 35 |
| KRT16 | keratin 16, type I |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LEPR | leptin receptor |
| LHX2 | LIM homeobox 2 |
| LOX | lysyl oxidase |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MST1 | macrophage stimulating 1 |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| NIPAL3 | NIPA-like domain containing 3 |
| NPY | neuropeptide Y |
| NUP88 | nucleoporin 88kDa |
| OLFML2B | olfactomedin-like 2B |
| ONECUT2 | one cut homeobox 2 |
| PCDH12 | protocadherin 12 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PEAK1 | pseudopodium-enriched atypical kinase 1 |
| PKP1 | plakophilin 1 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 |
| POU2F3 | POU class 2 homeobox 3 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSCA | prostate stem cell antigen |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| RAI2 | retinoic acid induced 2 |
| RGS10 | regulator of G-protein signaling 10 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 |
| SNTA1 | syntrophin, alpha 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SYCP1 | synaptonemal complex protein 1 |
| TAL1 | T-cell acute lymphocytic leukemia 1 |
| TAPBP | TAP binding protein (tapasin) |
| TCTN2 | tectonic family member 2 |
| TGFBR3 | transforming growth factor, beta receptor III |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TNS2 | tensin 2 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRIP6 | thyroid hormone receptor interactor 6 |
| TTC9 | tetratricopeptide repeat domain 9 |
| UPK3B | uroplakin 3B |
| USP46 | ubiquitin specific peptidase 46 |
| WDR62 | WD repeat domain 62 |
| WDR91 | WD repeat domain 91 |
| ZNF134 | zinc finger protein 134 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARTN | artemin |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCNO | cyclin O |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDC37 | cell division cycle 37 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CIC | capicua transcriptional repressor |
| CLSTN3 | calsyntenin 3 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DIXDC1 | DIX domain containing 1 |
| EGR3 | early growth response 3 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FHL2 | four and a half LIM domains 2 |
| FLT4 | fms-related tyrosine kinase 4 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| HIST1H2AL | histone cluster 1, H2al |
| HOXB2 | homeobox B2 |
| HOXC4 | homeobox C4 |
| HSPB8 | heat shock 22kDa protein 8 |
| ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IREB2 | iron-responsive element binding protein 2 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIAA0125 | KIAA0125 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP6D1 | MAP6 domain containing 1 |
| MEFV | Mediterranean fever |
| METTL8 | methyltransferase like 8 |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MORN1 | MORN repeat containing 1 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NPY1R | neuropeptide Y receptor Y1 |
| NUBPL | nucleotide binding protein-like |
| OLFML2A | olfactomedin-like 2A |
| OSMR | oncostatin M receptor |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PCDHB8 | protocadherin beta 8 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PORCN | porcupine homolog (Drosophila) |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PROCR | protein C receptor, endothelial |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RHOC | ras homolog family member C |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit |
| SIAH2 | siah E3 ubiquitin protein ligase 2 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 |
| SLC41A3 | solute carrier family 41, member 3 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| STC2 | stanniocalcin 2 |
| TBC1D17 | TBC1 domain family, member 17 |
| TMEM242 | transmembrane protein 242 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSPAN1 | tetraspanin 1 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UBQLN4 | ubiquilin 4 |
| VAX2 | ventral anterior homeobox 2 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF76 | zinc finger protein 76 |
