| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the fulvestrant-5969 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ACOT11 | acyl-CoA thioesterase 11 |
| AGBL3 | ATP/GTP binding protein-like 3 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| AHNAK | AHNAK nucleoprotein |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ANXA10 | annexin A10 |
| APOE | apolipoprotein E |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
| BEND5 | BEN domain containing 5 |
| BMP7 | bone morphogenetic protein 7 |
| CDK6 | cyclin-dependent kinase 6 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CFAP70 | cilia and flagella associated protein 70 |
| CHRNA10 | cholinergic receptor, nicotinic, alpha 10 (neuronal) |
| COL6A1 | collagen, type VI, alpha 1 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| DRD2 | dopamine receptor D2 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
| EMID1 | EMI domain containing 1 |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GLRX3 | glutaredoxin 3 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPATCH2L | G patch domain containing 2-like |
| GUK1 | guanylate kinase 1 |
| HAUS5 | HAUS augmin-like complex, subunit 5 |
| HIST1H1E | histone cluster 1, H1e |
| HOXB2 | homeobox B2 |
| HOXB5 | homeobox B5 |
| IL9R | interleukin 9 receptor |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KLHL22 | kelch-like family member 22 |
| KLK10 | kallikrein-related peptidase 10 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LOC100294391 | uncharacterized LOC100294391 |
| LPL | lipoprotein lipase |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MOXD1 | monooxygenase, DBH-like 1 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| NADK | NAD kinase |
| NCOA2 | nuclear receptor coactivator 2 |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| NRP1 | neuropilin 1 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OSR2 | odd-skipped related transciption factor 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PALM | paralemmin |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PCDHB3 | protocadherin beta 3 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PITX2 | paired-like homeodomain 2 |
| POLL | polymerase (DNA directed), lambda |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PRKCE | protein kinase C, epsilon |
| PSG11 | pregnancy specific beta-1-glycoprotein 11 |
| PTN | pleiotrophin |
| PVR | poliovirus receptor |
| RAB36 | RAB36, member RAS oncogene family |
| RASL11B | RAS-like, family 11, member B |
| RERE | arginine-glutamic acid dipeptide (RE) repeats |
| RNF39 | ring finger protein 39 |
| RNFT1 | ring finger protein, transmembrane 1 |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SH2D3A | SH2 domain containing 3A |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SLN | sarcolipin |
| SPRYD7 | SPRY domain containing 7 |
| STC2 | stanniocalcin 2 |
| TBC1D30 | TBC1 domain family, member 30 |
| TBX19 | T-box 19 |
| TBXA2R | thromboxane A2 receptor |
| TDRKH | tudor and KH domain containing |
| TM4SF20 | transmembrane 4 L six family member 20 |
| TMEM140 | transmembrane protein 140 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TP53 | tumor protein p53 |
| TPMT | thiopurine S-methyltransferase |
| TSC22D2 | TSC22 domain family, member 2 |
| TSC22D4 | TSC22 domain family, member 4 |
| UPF3A | UPF3 regulator of nonsense transcripts homolog A (yeast) |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| WAS | Wiskott-Aldrich syndrome |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZNF334 | zinc finger protein 334 |
| ZNF606 | zinc finger protein 606 |
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| AEN | apoptosis enhancing nuclease |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C3AR1 | complement component 3a receptor 1 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDK5R2 | cyclin-dependent kinase 5, regulatory subunit 2 (p39) |
| CENPJ | centromere protein J |
| CES3 | carboxylesterase 3 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| COL17A1 | collagen, type XVII, alpha 1 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| CPZ | carboxypeptidase Z |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP11A1 | cytochrome P450, family 11, subfamily A, polypeptide 1 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 |
| DKFZP434C153 | DKFZP434C153 protein |
| DNAL4 | dynein, axonemal, light chain 4 |
| DOC2B | double C2-like domains, beta |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| DSPP | dentin sialophosphoprotein |
| EGF | epidermal growth factor |
| F2RL2 | coagulation factor II (thrombin) receptor-like 2 |
| FAM110D | family with sequence similarity 110, member D |
| FLJ11710 | uncharacterized protein FLJ11710 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| HOXC11 | homeobox C11 |
| HOXC4 | homeobox C4 |
| HRH2 | histamine receptor H2 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| IL15RA | interleukin 15 receptor, alpha |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KCNE2 | potassium channel, voltage gated subfamily E regulatory beta subunit 2 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KCNMB2 | potassium channel subfamily M regulatory beta subunit 2 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIAA1456 | KIAA1456 |
| KLF13 | Kruppel-like factor 13 |
| KRT20 | keratin 20, type I |
| LRRC48 | leucine rich repeat containing 48 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| METTL16 | methyltransferase like 16 |
| MORN1 | MORN repeat containing 1 |
| MT1M | metallothionein 1M |
| MYH15 | myosin, heavy chain 15 |
| MYOZ1 | myozenin 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOTCH4 | notch 4 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NTF3 | neurotrophin 3 |
| NXPE4 | neurexophilin and PC-esterase domain family, member 4 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
| PCDHA5 | protocadherin alpha 5 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PIPOX | pipecolic acid oxidase |
| PLAG1 | pleiomorphic adenoma gene 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| RAB3B | RAB3B, member RAS oncogene family |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGCC | regulator of cell cycle |
| RNF122 | ring finger protein 122 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF2 | ring finger protein 2 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N |
| SOSTDC1 | sclerostin domain containing 1 |
| STK4 | serine/threonine kinase 4 |
| STON1 | stonin 1 |
| SYNGR3 | synaptogyrin 3 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| TFCP2L1 | transcription factor CP2-like 1 |
| TOM1 | target of myb1 (chicken) |
| TRIM25 | tripartite motif containing 25 |
| TUBB7P | tubulin, beta 7, pseudogene |
| VGF | VGF nerve growth factor inducible |
| WFDC8 | WAP four-disulfide core domain 8 |
| YOD1 | YOD1 deubiquitinase |
| ZNF222 | zinc finger protein 222 |
| ZNF254 | zinc finger protein 254 |
| ZNF639 | zinc finger protein 639 |
