| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the fulvestrant-6165 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB11 | ATP-binding cassette, sub-family B (MDR/TAP), member 11 |
| ADORA1 | adenosine A1 receptor |
| ALDOB | aldolase B, fructose-bisphosphate |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ATP10A | ATPase, class V, type 10A |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| BAGE | B melanoma antigen |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| CDHR2 | cadherin-related family member 2 |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CFAP69 | cilia and flagella associated protein 69 |
| CFHR2 | complement factor H-related 2 |
| CFI | complement factor I |
| CHI3L2 | chitinase 3-like 2 |
| CLEC4M | C-type lectin domain family 4, member M |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CSNK1E | casein kinase 1, epsilon |
| DDR1 | discoidin domain receptor tyrosine kinase 1 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DSCAM | Down syndrome cell adhesion molecule |
| EGFR | epidermal growth factor receptor |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| EPHB3 | EPH receptor B3 |
| FAM134B | family with sequence similarity 134, member B |
| FAM65B | family with sequence similarity 65, member B |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FGF6 | fibroblast growth factor 6 |
| FLT1 | fms-related tyrosine kinase 1 |
| GAS8 | growth arrest-specific 8 |
| GDF5 | growth differentiation factor 5 |
| GPATCH4 | G patch domain containing 4 |
| GSTA1 | glutathione S-transferase alpha 1 |
| HAP1 | huntingtin-associated protein 1 |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 |
| HFE | hemochromatosis |
| HIST1H4E | histone cluster 1, H4e |
| HRG | histidine-rich glycoprotein |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 |
| ISL1 | ISL LIM homeobox 1 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIR3DS1 | killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LMTK1 | lemur tail kinase 1 |
| LOXL3 | lysyl oxidase-like 3 |
| LPAR1 | lysophosphatidic acid receptor 1 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
| MSC | musculin |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 |
| NEU3 | sialidase 3 (membrane sialidase) |
| NLRP1 | NLR family, pyrin domain containing 1 |
| NOTCH4 | notch 4 |
| NPR3 | natriuretic peptide receptor 3 |
| NPY2R | neuropeptide Y receptor Y2 |
| NRG1 | neuregulin 1 |
| OLFML3 | olfactomedin-like 3 |
| PCDHA6 | protocadherin alpha 6 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PDE8B | phosphodiesterase 8B |
| PHC3 | polyhomeotic homolog 3 (Drosophila) |
| PLCD1 | phospholipase C, delta 1 |
| PLCH1 | phospholipase C, eta 1 |
| PON3 | paraoxonase 3 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PXDC1 | PX domain containing 1 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RNF17 | ring finger protein 17 |
| ROBO4 | roundabout, axon guidance receptor, homolog 4 (Drosophila) |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| SAMD4A | sterile alpha motif domain containing 4A |
| SEMA6B | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SFTPB | surfactant protein B |
| SH3BP2 | SH3-domain binding protein 2 |
| SHB | Src homology 2 domain containing adaptor protein B |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLCO1A2 | solute carrier organic anion transporter family, member 1A2 |
| SNCG | synuclein, gamma (breast cancer-specific protein 1) |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TBC1D16 | TBC1 domain family, member 16 |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TEF | thyrotrophic embryonic factor |
| TFF2 | trefoil factor 2 |
| THBS1 | thrombospondin 1 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM144 | transmembrane protein 144 |
| TMEM53 | transmembrane protein 53 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TPD52L1 | tumor protein D52-like 1 |
| TTC21B | tetratricopeptide repeat domain 21B |
| TUBG2 | tubulin, gamma 2 |
| ULK2 | unc-51 like autophagy activating kinase 2 |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABHD17B | abhydrolase domain containing 17B |
| AMT | aminomethyltransferase |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ASGR2 | asialoglycoprotein receptor 2 |
| BBC3 | BCL2 binding component 3 |
| BBS10 | Bardet-Biedl syndrome 10 |
| BCL7C | B-cell CLL/lymphoma 7C |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CCDC106 | coiled-coil domain containing 106 |
| CPTP | ceramide-1-phosphate transfer protein |
| CTSV | cathepsin V |
| CXORF56 | chromosome X open reading frame 56 |
| DBF4B | DBF4 zinc finger B |
| DDN | dendrin |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DNAL4 | dynein, axonemal, light chain 4 |
| DOCK4 | dedicator of cytokinesis 4 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FAM168B | family with sequence similarity 168, member B |
| FCHO1 | FCH domain only 1 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FKBP5 | FK506 binding protein 5 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GPATCH2L | G patch domain containing 2-like |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HINFP | histone H4 transcription factor |
| HIRA | histone cell cycle regulator |
| HOXA1 | homeobox A1 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| INO80D | INO80 complex subunit D |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KLK5 | kallikrein-related peptidase 5 |
| LPAR2 | lysophosphatidic acid receptor 2 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAP6D1 | MAP6 domain containing 1 |
| MED22 | mediator complex subunit 22 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MKL2 | MKL/myocardin-like 2 |
| MKS1 | Meckel syndrome, type 1 |
| MRPL28 | mitochondrial ribosomal protein L28 |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PDGFD | platelet derived growth factor D |
| PHACTR4 | phosphatase and actin regulator 4 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIAS3 | protein inhibitor of activated STAT, 3 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLM | polymerase (DNA directed), mu |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RETN | resistin |
| RFWD3 | ring finger and WD repeat domain 3 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RUSC2 | RUN and SH3 domain containing 2 |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SALL2 | spalt-like transcription factor 2 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SNAI1 | snail family zinc finger 1 |
| SPAG1 | sperm associated antigen 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TEP1 | telomerase-associated protein 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TFPT | TCF3 (E2A) fusion partner (in childhood Leukemia) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM134 | transmembrane protein 134 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRPV2 | transient receptor potential cation channel, subfamily V, member 2 |
| UNC119 | unc-119 homolog (C. elegans) |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF215 | zinc finger protein 215 |
| ZNF232 | zinc finger protein 232 |
| ZNF264 | zinc finger protein 264 |
| ZNF652 | zinc finger protein 652 |
| ZNF668 | zinc finger protein 668 |
| ZNF91 | zinc finger protein 91 |
