| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the fulvestrant-6867 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AK1 | adenylate kinase 1 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANXA10 | annexin A10 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| BCL2L1 | BCL2-like 1 |
| BCOR | BCL6 corepressor |
| BTBD7 | BTB (POZ) domain containing 7 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CACYBP | calcyclin binding protein |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CDK3 | cyclin-dependent kinase 3 |
| CHI3L2 | chitinase 3-like 2 |
| CLDN17 | claudin 17 |
| COL6A1 | collagen, type VI, alpha 1 |
| CORO2A | coronin, actin binding protein, 2A |
| CORT | cortistatin |
| CUL4B | cullin 4B |
| CWH43 | cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) |
| DLX2 | distal-less homeobox 2 |
| DUS4L | dihydrouridine synthase 4-like (S. cerevisiae) |
| ELK1 | ELK1, member of ETS oncogene family |
| EXT1 | exostosin glycosyltransferase 1 |
| FAM53B | family with sequence similarity 53, member B |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| FZD7 | frizzled class receptor 7 |
| GBX2 | gastrulation brain homeobox 2 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GPR107 | G protein-coupled receptor 107 |
| HDAC5 | histone deacetylase 5 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IGF1R | insulin-like growth factor 1 receptor |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL15RA | interleukin 15 receptor, alpha |
| IL17RC | interleukin 17 receptor C |
| IRF5 | interferon regulatory factor 5 |
| KIAA0368 | KIAA0368 |
| KLF4 | Kruppel-like factor 4 (gut) |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LMF1 | lipase maturation factor 1 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| MAGEA12 | melanoma antigen family A12 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MCM4 | minichromosome maintenance complex component 4 |
| MDM1 | Mdm1 nuclear protein homolog (mouse) |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MOB3B | MOB kinase activator 3B |
| MVK | mevalonate kinase |
| N4BP1 | NEDD4 binding protein 1 |
| NDP | Norrie disease (pseudoglioma) |
| NFYA | nuclear transcription factor Y, alpha |
| NFYC | nuclear transcription factor Y, gamma |
| NIPAL2 | NIPA-like domain containing 2 |
| NPR3 | natriuretic peptide receptor 3 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OCRL | oculocerebrorenal syndrome of Lowe |
| PEX3 | peroxisomal biogenesis factor 3 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLK3 | polo-like kinase 3 |
| PMS2P2 | postmeiotic segregation increased 2 pseudogene 2 |
| POLL | polymerase (DNA directed), lambda |
| PTK2B | protein tyrosine kinase 2 beta |
| PVR | poliovirus receptor |
| RARG | retinoic acid receptor, gamma |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RNF39 | ring finger protein 39 |
| RRP1B | ribosomal RNA processing 1B |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SBF1 | SET binding factor 1 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| STX7 | syntaxin 7 |
| SUMO1 | small ubiquitin-like modifier 1 |
| SUN1 | Sad1 and UNC84 domain containing 1 |
| TDRD3 | tudor domain containing 3 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 |
| TMEM209 | transmembrane protein 209 |
| TUSC3 | tumor suppressor candidate 3 |
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 |
| UBE3A | ubiquitin protein ligase E3A |
| UBXN1 | UBX domain protein 1 |
| WDR1 | WD repeat domain 1 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF552 | zinc finger protein 552 |
| Symbol | Name |
|---|---|
| ACOT8 | acyl-CoA thioesterase 8 |
| ADAMTS20 | ADAM metallopeptidase with thrombospondin type 1 motif, 20 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP4B | ATPase, H+/K+ exchanging, beta polypeptide |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BTBD18 | BTB (POZ) domain containing 18 |
| C1ORF95 | chromosome 1 open reading frame 95 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C8B | complement component 8, beta polypeptide |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CCDC40 | coiled-coil domain containing 40 |
| CCL22 | chemokine (C-C motif) ligand 22 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD300C | CD300c molecule |
| CDK20 | cyclin-dependent kinase 20 |
| CLDN1 | claudin 1 |
| CLDN11 | claudin 11 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CNPY4 | canopy FGF signaling regulator 4 |
| CNTFR | ciliary neurotrophic factor receptor |
| CNTNAP3B | contactin associated protein-like 3B |
| CPA4 | carboxypeptidase A4 |
| CTF1 | cardiotrophin 1 |
| CTRC | chymotrypsin C (caldecrin) |
| CTSK | cathepsin K |
| CXORF21 | chromosome X open reading frame 21 |
| EGFL7 | EGF-like-domain, multiple 7 |
| FABP6 | fatty acid binding protein 6, ileal |
| FAM120C | family with sequence similarity 120C |
| FAM186A | family with sequence similarity 186, member A |
| FBXO22 | F-box protein 22 |
| FGL1 | fibrinogen-like 1 |
| FOXC1 | forkhead box C1 |
| GALK1 | galactokinase 1 |
| GPR1 | G protein-coupled receptor 1 |
| GPR39 | G protein-coupled receptor 39 |
| GUCA1B | guanylate cyclase activator 1B (retina) |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HSPA1L | heat shock 70kDa protein 1-like |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL22 | interleukin 22 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KDM4D | lysine (K)-specific demethylase 4D |
| KIAA1324 | KIAA1324 |
| KIF13A | kinesin family member 13A |
| KLK1 | kallikrein 1 |
| LIPG | lipase, endothelial |
| LMTK1 | lemur tail kinase 1 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LY6G5C | lymphocyte antigen 6 complex, locus G5C |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MIP | major intrinsic protein of lens fiber |
| NEK11 | NIMA-related kinase 11 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| OSMR | oncostatin M receptor |
| PAQR5 | progestin and adipoQ receptor family member V |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PHOX2B | paired-like homeobox 2b |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 |
| PLXNA3 | plexin A3 |
| PNPLA3 | patatin-like phospholipase domain containing 3 |
| POMT2 | protein-O-mannosyltransferase 2 |
| RASAL2 | RAS protein activator like 2 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RHBDD3 | rhomboid domain containing 3 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF208 | ring finger protein 208 |
| RORC | RAR-related orphan receptor C |
| SELPLG | selectin P ligand |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SIRT6 | sirtuin 6 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLC5A1 | solute carrier family 5 (sodium/glucose cotransporter), member 1 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TMEM212 | transmembrane protein 212 |
| TMPRSS6 | transmembrane protease, serine 6 |
| UGT8 | UDP glycosyltransferase 8 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZNF212 | zinc finger protein 212 |
| ZNF219 | zinc finger protein 219 |
| ZNF667 | zinc finger protein 667 |
| ZNF671 | zinc finger protein 671 |
| ZNF747 | zinc finger protein 747 |