| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the fulvestrant-6918 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACB | acetyl-CoA carboxylase beta |
| ANKRD12 | ankyrin repeat domain 12 |
| ARG2 | arginase 2 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATF5 | activating transcription factor 5 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| BICD2 | bicaudal D homolog 2 (Drosophila) |
| C12ORF29 | chromosome 12 open reading frame 29 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CEP290 | centrosomal protein 290kDa |
| CLCN3 | chloride channel, voltage-sensitive 3 |
| CPE | carboxypeptidase E |
| CPNE3 | copine III |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXORF56 | chromosome X open reading frame 56 |
| DSC2 | desmocollin 2 |
| DYNC2LI1 | dynein, cytoplasmic 2, light intermediate chain 1 |
| E2F8 | E2F transcription factor 8 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
| EGF | epidermal growth factor |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 |
| ELMO2 | engulfment and cell motility 2 |
| FAM149B1 | family with sequence similarity 149, member B1 |
| FAS | Fas cell surface death receptor |
| FGF2 | fibroblast growth factor 2 (basic) |
| GPC4 | glypican 4 |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 |
| HOOK1 | hook microtubule-tethering protein 1 |
| HOXB5 | homeobox B5 |
| HSPG2 | heparan sulfate proteoglycan 2 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IMPACT | impact RWD domain protein |
| IQGAP1 | IQ motif containing GTPase activating protein 1 |
| IRF2 | interferon regulatory factor 2 |
| KIAA0100 | KIAA0100 |
| KIAA0485 | uncharacterized LOC57235 |
| KLHL24 | kelch-like family member 24 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog |
| LRP12 | low density lipoprotein receptor-related protein 12 |
| LYPLA1 | lysophospholipase I |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MDM1 | Mdm1 nuclear protein homolog (mouse) |
| MED13L | mediator complex subunit 13-like |
| NAA60 | N(alpha)-acetyltransferase 60, NatF catalytic subunit |
| NBN | nibrin |
| NME5 | NME/NM23 family member 5 |
| NMT2 | N-myristoyltransferase 2 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OSBPL3 | oxysterol binding protein-like 3 |
| OXR1 | oxidation resistance 1 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PGK1 | phosphoglycerate kinase 1 |
| PHF3 | PHD finger protein 3 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PNISR | PNN-interacting serine/arginine-rich protein |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PRMT2 | protein arginine methyltransferase 2 |
| PRRC2C | proline-rich coiled-coil 2C |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RBL2 | retinoblastoma-like 2 |
| RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) |
| RPL14 | ribosomal protein L14 |
| RPL38 | ribosomal protein L38 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) |
| SETDB1 | SET domain, bifurcated 1 |
| SF1 | splicing factor 1 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| TBC1D30 | TBC1 domain family, member 30 |
| TBL1X | transducin (beta)-like 1X-linked |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TGFBR3 | transforming growth factor, beta receptor III |
| TGIF2 | TGFB-induced factor homeobox 2 |
| TGOLN2 | trans-golgi network protein 2 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TPP2 | tripeptidyl peptidase II |
| TPR | translocated promoter region, nuclear basket protein |
| TWF1 | twinfilin actin binding protein 1 |
| UBOX5 | U-box domain containing 5 |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| USF2 | upstream transcription factor 2, c-fos interacting |
| USP6 | ubiquitin specific peptidase 6 |
| WWC2 | WW and C2 domain containing 2 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZCCHC10 | zinc finger, CCHC domain containing 10 |
| ZFX | zinc finger protein, X-linked |
| ZNF107 | zinc finger protein 107 |
| ZNF668 | zinc finger protein 668 |
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 |
| ALG3 | ALG3, alpha-1,3- mannosyltransferase |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARAF | A-Raf proto-oncogene, serine/threonine kinase |
| ARL2 | ADP-ribosylation factor-like 2 |
| ASNA1 | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| BSG | basigin (Ok blood group) |
| C11ORF80 | chromosome 11 open reading frame 80 |
| CAPNS1 | calpain, small subunit 1 |
| CDA | cytidine deaminase |
| CDC37 | cell division cycle 37 |
| CEP85 | centrosomal protein 85kDa |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CRIP2 | cysteine-rich protein 2 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CYB5R1 | cytochrome b5 reductase 1 |
| CYB5R2 | cytochrome b5 reductase 2 |
| DCLRE1A | DNA cross-link repair 1A |
| DDA1 | DET1 and DDB1 associated 1 |
| DEAF1 | DEAF1 transcription factor |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DENND5B | DENN/MADD domain containing 5B |
| DPM2 | dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit |
| EDC3 | enhancer of mRNA decapping 3 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| EML4 | echinoderm microtubule associated protein like 4 |
| EMP3 | epithelial membrane protein 3 |
| ERI3 | ERI1 exoribonuclease family member 3 |
| FAM86C1 | family with sequence similarity 86, member C1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GLTP | glycolipid transfer protein |
| GMIP | GEM interacting protein |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GRPR | gastrin-releasing peptide receptor |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| GYS1 | glycogen synthase 1 (muscle) |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IFI30 | interferon, gamma-inducible protein 30 |
| IFI6 | interferon, alpha-inducible protein 6 |
| JUNB | jun B proto-oncogene |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LOXL1 | lysyl oxidase-like 1 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MLF2 | myeloid leukemia factor 2 |
| MOSPD3 | motile sperm domain containing 3 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MTA2 | metastasis associated 1 family, member 2 |
| NUTF2 | nuclear transport factor 2 |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PCDH12 | protocadherin 12 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PGD | phosphogluconate dehydrogenase |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) |
| POGK | pogo transposable element with KRAB domain |
| POLR2J | polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa |
| POLR2J2 | polymerase (RNA) II (DNA directed) polypeptide J2 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme |
| PRMT5 | protein arginine methyltransferase 5 |
| PRPF8 | pre-mRNA processing factor 8 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSENEN | presenilin enhancer gamma secretase subunit |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RRAS | related RAS viral (r-ras) oncogene homolog |
| SAMD9 | sterile alpha motif domain containing 9 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 |
| SHARPIN | SHANK-associated RH domain interactor |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC41A3 | solute carrier family 41, member 3 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| SYTL2 | synaptotagmin-like 2 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TCTN2 | tectonic family member 2 |
| TECR | trans-2,3-enoyl-CoA reductase |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM212 | transmembrane protein 212 |
| TMEM230 | transmembrane protein 230 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TOR4A | torsin family 4, member A |
| TRABD | TraB domain containing |
| TRAPPC2L | trafficking protein particle complex 2-like |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TSPAN1 | tetraspanin 1 |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| UBE2M | ubiquitin-conjugating enzyme E2M |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| YIPF5 | Yip1 domain family, member 5 |
