| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the fulvestrant-704 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| ATG12 | autophagy related 12 |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
| BSPRY | B-box and SPRY domain containing |
| C12ORF29 | chromosome 12 open reading frame 29 |
| C2CD5 | C2 calcium-dependent domain containing 5 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CBX6 | chromobox homolog 6 |
| CCBL2 | cysteine conjugate-beta lyase 2 |
| CCDC85B | coiled-coil domain containing 85B |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CENPN | centromere protein N |
| CERS6 | ceramide synthase 6 |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) |
| CLTB | clathrin, light chain B |
| CLU | clusterin |
| CREM | cAMP responsive element modulator |
| CUL4B | cullin 4B |
| DAXX | death-domain associated protein |
| DHFR | dihydrofolate reductase |
| DUS2 | dihydrouridine synthase 2 |
| EIF2B3 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa |
| EIF3J | eukaryotic translation initiation factor 3, subunit J |
| FASTKD3 | FAST kinase domains 3 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FH | fumarate hydratase |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FUBP3 | far upstream element (FUSE) binding protein 3 |
| GOLGA1 | golgin A1 |
| GPR87 | G protein-coupled receptor 87 |
| GSTT1 | glutathione S-transferase theta 1 |
| HEATR1 | HEAT repeat containing 1 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOXA4 | homeobox A4 |
| HTT | huntingtin |
| INHBC | inhibin, beta C |
| IQCE | IQ motif containing E |
| ISCA1 | iron-sulfur cluster assembly 1 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIAA0195 | KIAA0195 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| MAP3K7 | mitogen-activated protein kinase kinase kinase 7 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MRPL19 | mitochondrial ribosomal protein L19 |
| MTMR6 | myotubularin related protein 6 |
| MTSS1 | metastasis suppressor 1 |
| MYL10 | myosin, light chain 10, regulatory |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NCOA1 | nuclear receptor coactivator 1 |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NINJ1 | ninjurin 1 |
| NNMT | nicotinamide N-methyltransferase |
| NOV | nephroblastoma overexpressed |
| NTAN1 | N-terminal asparagine amidase |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| NUCB2 | nucleobindin 2 |
| NXT2 | nuclear transport factor 2-like export factor 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PEMT | phosphatidylethanolamine N-methyltransferase |
| PLAUR | plasminogen activator, urokinase receptor |
| PLCB4 | phospholipase C, beta 4 |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein |
| PLSCR3 | phospholipid scramblase 3 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PSAP | prosaposin |
| RITA1 | RBPJ interacting and tubulin associated 1 |
| RNF141 | ring finger protein 141 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RWDD1 | RWD domain containing 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SIK3 | SIK family kinase 3 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 |
| SMC3 | structural maintenance of chromosomes 3 |
| SOCS5 | suppressor of cytokine signaling 5 |
| STAC | SH3 and cysteine rich domain |
| STK19 | serine/threonine kinase 19 |
| SYF2 | SYF2 pre-mRNA-splicing factor |
| TBRG4 | transforming growth factor beta regulator 4 |
| TDG | thymine-DNA glycosylase |
| THOC1 | THO complex 1 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TSPAN31 | tetraspanin 31 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| YTHDC2 | YTH domain containing 2 |
| ZCCHC11 | zinc finger, CCHC domain containing 11 |
| Symbol | Name |
|---|---|
| AACS | acetoacetyl-CoA synthetase |
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACBD4 | acyl-CoA binding domain containing 4 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| ARMC4 | armadillo repeat containing 4 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| ATXN2 | ataxin 2 |
| AXIN1 | axin 1 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| BTNL3 | butyrophilin-like 3 |
| CA7 | carbonic anhydrase VII |
| CCDC176 | coiled-coil domain containing 176 |
| CCNA1 | cyclin A1 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CDA | cytidine deaminase |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
| CHEK2 | checkpoint kinase 2 |
| COG4 | component of oligomeric golgi complex 4 |
| CTAGE9 | CTAGE family, member 9 |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DYSF | dysferlin |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| FAM102A | family with sequence similarity 102, member A |
| FAM155B | family with sequence similarity 155, member B |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FASTKD1 | FAST kinase domains 1 |
| FMOD | fibromodulin |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| G6PC2 | glucose-6-phosphatase, catalytic, 2 |
| GBX2 | gastrulation brain homeobox 2 |
| GPR12 | G protein-coupled receptor 12 |
| GPR21 | G protein-coupled receptor 21 |
| GTF2I | general transcription factor IIi |
| HIST1H2BC | histone cluster 1, H2bc |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H4J | histone cluster 1, H4j |
| HMX1 | H6 family homeobox 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IPO8 | importin 8 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KLHL21 | kelch-like family member 21 |
| KLK6 | kallikrein-related peptidase 6 |
| LCT | lactase |
| LINC00216 | long intergenic non-protein coding RNA 216 |
| LMBR1L | limb development membrane protein 1-like |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAPK10 | mitogen-activated protein kinase 10 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MGA | MGA, MAX dimerization protein |
| MNT | MAX network transcriptional repressor |
| MSX1 | msh homeobox 1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| NUDT3 | nudix (nucleoside diphosphate linked moiety X)-type motif 3 |
| OCLM | oculomedin |
| OLFML2A | olfactomedin-like 2A |
| OMG | oligodendrocyte myelin glycoprotein |
| OR1F1 | olfactory receptor, family 1, subfamily F, member 1 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PIGR | polymeric immunoglobulin receptor |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PMEL | premelanosome protein |
| POLD1 | polymerase (DNA directed), delta 1, catalytic subunit |
| POR | P450 (cytochrome) oxidoreductase |
| POU5F1B | POU class 5 homeobox 1B |
| RLBP1 | retinaldehyde binding protein 1 |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPS17P5 | ribosomal protein S17 pseudogene 5 |
| RRP1 | ribosomal RNA processing 1 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC43A1 | solute carrier family 43 (amino acid system L transporter), member 1 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SPECC1L | sperm antigen with calponin homology and coiled-coil domains 1-like |
| SSBP3 | single stranded DNA binding protein 3 |
| STAP2 | signal transducing adaptor family member 2 |
| SYT13 | synaptotagmin XIII |
| TBC1D16 | TBC1 domain family, member 16 |
| TFCP2L1 | transcription factor CP2-like 1 |
| TJP2 | tight junction protein 2 |
| TMEM243 | transmembrane protein 243, mitochondrial |
| TRAPPC12 | trafficking protein particle complex 12 |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WDR19 | WD repeat domain 19 |
| WDR5B | WD repeat domain 5B |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZNF280A | zinc finger protein 280A |
