| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the fulvestrant-7091 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABR | active BCR-related |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ARFRP1 | ADP-ribosylation factor related protein 1 |
| ATXN2L | ataxin 2-like |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BTG2 | BTG family, member 2 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CA11 | carbonic anhydrase XI |
| CCNG2 | cyclin G2 |
| CDK2 | cyclin-dependent kinase 2 |
| CDK3 | cyclin-dependent kinase 3 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COL1A1 | collagen, type I, alpha 1 |
| CPQ | carboxypeptidase Q |
| CST6 | cystatin E/M |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| EPHA3 | EPH receptor A3 |
| EPOR | erythropoietin receptor |
| EPS8L1 | EPS8-like 1 |
| EXPH5 | exophilin 5 |
| F2R | coagulation factor II (thrombin) receptor |
| FAM131A | family with sequence similarity 131, member A |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GLRX | glutaredoxin (thioltransferase) |
| GRB7 | growth factor receptor-bound protein 7 |
| HDAC11 | histone deacetylase 11 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| ING1 | inhibitor of growth family, member 1 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KDM6A | lysine (K)-specific demethylase 6A |
| KIF1C | kinesin family member 1C |
| KIF22 | kinesin family member 22 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LGALS8 | lectin, galactoside-binding, soluble, 8 |
| LMF2 | lipase maturation factor 2 |
| LONP2 | lon peptidase 2, peroxisomal |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MTUS1 | microtubule associated tumor suppressor 1 |
| MXD4 | MAX dimerization protein 4 |
| NEK2 | NIMA-related kinase 2 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OBSL1 | obscurin-like 1 |
| PARPBP | PARP1 binding protein |
| PCDH1 | protocadherin 1 |
| PCDH7 | protocadherin 7 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PEX14 | peroxisomal biogenesis factor 14 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PML | promyelocytic leukemia |
| PMP22 | peripheral myelin protein 22 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| POFUT1 | protein O-fucosyltransferase 1 |
| POGZ | pogo transposable element with ZNF domain |
| PRUNE | prune exopolyphosphatase |
| PTCD2 | pentatricopeptide repeat domain 2 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB27B | RAB27B, member RAS oncogene family |
| RBM8A | RNA binding motif protein 8A |
| RECQL5 | RecQ protein-like 5 |
| RGS10 | regulator of G-protein signaling 10 |
| RNF25 | ring finger protein 25 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SMAD3 | SMAD family member 3 |
| SPAG9 | sperm associated antigen 9 |
| SREBF2 | sterol regulatory element binding transcription factor 2 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) |
| TBC1D22A | TBC1 domain family, member 22A |
| TGM2 | transglutaminase 2 |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TRAF4 | TNF receptor-associated factor 4 |
| TRAIP | TRAF interacting protein |
| TSPYL2 | TSPY-like 2 |
| TUBA3C | tubulin, alpha 3c |
| UBXN1 | UBX domain protein 1 |
| ZNF16 | zinc finger protein 16 |
| ZNF350 | zinc finger protein 350 |
| ZNF467 | zinc finger protein 467 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ACVR2B | activin A receptor, type IIB |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BBS7 | Bardet-Biedl syndrome 7 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCL2L13 | BCL2-like 13 (apoptosis facilitator) |
| C6ORF47 | chromosome 6 open reading frame 47 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
| CCDC57 | coiled-coil domain containing 57 |
| CCDC88C | coiled-coil domain containing 88C |
| CCND1 | cyclin D1 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CES3 | carboxylesterase 3 |
| CHUK | conserved helix-loop-helix ubiquitous kinase |
| CISH | cytokine inducible SH2-containing protein |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase |
| CUEDC1 | CUE domain containing 1 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| DSCAM | Down syndrome cell adhesion molecule |
| DUSP13 | dual specificity phosphatase 13 |
| EGR3 | early growth response 3 |
| FAM102A | family with sequence similarity 102, member A |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXO22 | F-box protein 22 |
| FHL2 | four and a half LIM domains 2 |
| FOXC1 | forkhead box C1 |
| GBAS | glioblastoma amplified sequence |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HSPB8 | heat shock 22kDa protein 8 |
| IER3 | immediate early response 3 |
| IL15RA | interleukin 15 receptor, alpha |
| IL17RB | interleukin 17 receptor B |
| IREB2 | iron-responsive element binding protein 2 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KLF10 | Kruppel-like factor 10 |
| KLF11 | Kruppel-like factor 11 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRT13 | keratin 13, type I |
| MANSC1 | MANSC domain containing 1 |
| METTL8 | methyltransferase like 8 |
| MICB | MHC class I polypeptide-related sequence B |
| MITF | microphthalmia-associated transcription factor |
| MPPED2 | metallophosphoesterase domain containing 2 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 |
| NLK | nemo-like kinase |
| NOC3L | nucleolar complex associated 3 homolog (S. cerevisiae) |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NPY1R | neuropeptide Y receptor Y1 |
| NPY5R | neuropeptide Y receptor Y5 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRR3 | proline rich 3 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| PUS1 | pseudouridylate synthase 1 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SDCCAG3 | serologically defined colon cancer antigen 3 |
| SFMBT1 | Scm-like with four mbt domains 1 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SIAH2 | siah E3 ubiquitin protein ligase 2 |
| SMAD7 | SMAD family member 7 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNHG3 | small nucleolar RNA host gene 3 |
| SOAT1 | sterol O-acyltransferase 1 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPAG4 | sperm associated antigen 4 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| STC2 | stanniocalcin 2 |
| STK25 | serine/threonine kinase 25 |
| TH | tyrosine hydroxylase |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM120B | transmembrane protein 120B |
| TMEM121 | transmembrane protein 121 |
| TMEM164 | transmembrane protein 164 |
| TNRC6B | trinucleotide repeat containing 6B |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TTC26 | tetratricopeptide repeat domain 26 |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR3 | WD repeat domain 3 |
| XBP1 | X-box binding protein 1 |
| XK | X-linked Kx blood group |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZFP30 | ZFP30 zinc finger protein |