| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the fulvestrant-7490 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| BCL2L1 | BCL2-like 1 |
| BLNK | B-cell linker |
| BTBD7 | BTB (POZ) domain containing 7 |
| BTG2 | BTG family, member 2 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCNG2 | cyclin G2 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| COL1A1 | collagen, type I, alpha 1 |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DXO | decapping exoribonuclease |
| EPHA3 | EPH receptor A3 |
| ESR1 | estrogen receptor 1 |
| FEM1B | fem-1 homolog b (C. elegans) |
| FGFR2 | fibroblast growth factor receptor 2 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLOT1 | flotillin 1 |
| FLOT2 | flotillin 2 |
| FNDC3A | fibronectin type III domain containing 3A |
| FNTB | farnesyltransferase, CAAX box, beta |
| GAMT | guanidinoacetate N-methyltransferase |
| GK | glycerol kinase |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GM2A | GM2 ganglioside activator |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GRM4 | glutamate receptor, metabotropic 4 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IGHM | immunoglobulin heavy constant mu |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL1A | interleukin 1, alpha |
| ING4 | inhibitor of growth family, member 4 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KIAA1109 | KIAA1109 |
| KIF22 | kinesin family member 22 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| LIMCH1 | LIM and calponin homology domains 1 |
| LOC257152 | uncharacterized LOC257152 |
| LRRC14 | leucine rich repeat containing 14 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MCL1 | myeloid cell leukemia 1 |
| MDFI | MyoD family inhibitor |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MED20 | mediator complex subunit 20 |
| NCOA2 | nuclear receptor coactivator 2 |
| NF1 | neurofibromin 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| OGFR | opioid growth factor receptor |
| OSBPL7 | oxysterol binding protein-like 7 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PDCD6 | programmed cell death 6 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PML | promyelocytic leukemia |
| PRLR | prolactin receptor |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| RARG | retinoic acid receptor, gamma |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SPAG8 | sperm associated antigen 8 |
| SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| STIP1 | stress-induced phosphoprotein 1 |
| STMN1 | stathmin 1 |
| STON1 | stonin 1 |
| TAF7L | TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa |
| TBC1D5 | TBC1 domain family, member 5 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM259 | transmembrane protein 259 |
| TOX4 | TOX high mobility group box family member 4 |
| TPP1 | tripeptidyl peptidase I |
| TRIM23 | tripartite motif containing 23 |
| TSC22D3 | TSC22 domain family, member 3 |
| WDR1 | WD repeat domain 1 |
| ZDHHC17 | zinc finger, DHHC-type containing 17 |
| ZNF350 | zinc finger protein 350 |
| ZNF532 | zinc finger protein 532 |
| ZNF639 | zinc finger protein 639 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
| Symbol | Name |
|---|---|
| APOC4 | apolipoprotein C-IV |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARTN | artemin |
| BARX2 | BARX homeobox 2 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BFSP1 | beaded filament structural protein 1, filensin |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CCDC88C | coiled-coil domain containing 88C |
| CCND1 | cyclin D1 |
| CD48 | CD48 molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CHSY1 | chondroitin sulfate synthase 1 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CST6 | cystatin E/M |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DEFA4 | defensin, alpha 4, corticostatin |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DPF1 | D4, zinc and double PHD fingers family 1 |
| EGR3 | early growth response 3 |
| FAM110B | family with sequence similarity 110, member B |
| FER | fer (fps/fes related) tyrosine kinase |
| FHL2 | four and a half LIM domains 2 |
| FJX1 | four jointed box 1 (Drosophila) |
| FOSL1 | FOS-like antigen 1 |
| GATA4 | GATA binding protein 4 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GPR157 | G protein-coupled receptor 157 |
| GPR21 | G protein-coupled receptor 21 |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| GRPR | gastrin-releasing peptide receptor |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HHAT | hedgehog acyltransferase |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4C | histone cluster 1, H4c |
| HOXA3 | homeobox A3 |
| IER3 | immediate early response 3 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IL17RB | interleukin 17 receptor B |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| JAK2 | Janus kinase 2 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLF10 | Kruppel-like factor 10 |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| MAK | male germ cell-associated kinase |
| MAP6D1 | MAP6 domain containing 1 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MICB | MHC class I polypeptide-related sequence B |
| MNMIP1 | manchette microtubule inner protein 1 |
| MPPED2 | metallophosphoesterase domain containing 2 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NOL10 | nucleolar protein 10 |
| NPY1R | neuropeptide Y receptor Y1 |
| NRDE2 | NRDE-2, necessary for RNA interference, domain containing |
| ONECUT2 | one cut homeobox 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PDE8B | phosphodiesterase 8B |
| PIPOX | pipecolic acid oxidase |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PQLC2 | PQ loop repeat containing 2 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PTGES | prostaglandin E synthase |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RASIP1 | Ras interacting protein 1 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RBL1 | retinoblastoma-like 1 |
| RHBDD3 | rhomboid domain containing 3 |
| RLN1 | relaxin 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SDCCAG3 | serologically defined colon cancer antigen 3 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SMAD7 | SMAD family member 7 |
| STC2 | stanniocalcin 2 |
| STXBP5L | syntaxin binding protein 5-like |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SYBU | syntabulin (syntaxin-interacting) |
| SYNPO | synaptopodin |
| TCP11 | t-complex 11, testis-specific |
| TCTN2 | tectonic family member 2 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM183A | transmembrane protein 183A |
| TMEM62 | transmembrane protein 62 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| USP36 | ubiquitin specific peptidase 36 |
| ZNF205 | zinc finger protein 205 |
