| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the fulvestrant-7534 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADM | adrenomedullin |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ALCAM | activated leukocyte cell adhesion molecule |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| BBS9 | Bardet-Biedl syndrome 9 |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CAPN9 | calpain 9 |
| CCNG2 | cyclin G2 |
| CEP250 | centrosomal protein 250kDa |
| CFAP44 | cilia and flagella associated protein 44 |
| CLASP2 | cytoplasmic linker associated protein 2 |
| CNTNAP1 | contactin associated protein 1 |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CYHR1 | cysteine/histidine-rich 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DIAPH2 | diaphanous-related formin 2 |
| DNAH3 | dynein, axonemal, heavy chain 3 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DOPEY2 | dopey family member 2 |
| DSCR3 | Down syndrome critical region 3 |
| DUSP10 | dual specificity phosphatase 10 |
| DZIP3 | DAZ interacting zinc finger protein 3 |
| EGFR | epidermal growth factor receptor |
| EMID1 | EMI domain containing 1 |
| EPHB4 | EPH receptor B4 |
| EPS8L1 | EPS8-like 1 |
| FBLN1 | fibulin 1 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GK | glycerol kinase |
| GM2A | GM2 ganglioside activator |
| GRB7 | growth factor receptor-bound protein 7 |
| GYG2 | glycogenin 2 |
| HBEGF | heparin-binding EGF-like growth factor |
| HIST1H2AI | histone cluster 1, H2ai |
| IL17RC | interleukin 17 receptor C |
| IQCE | IQ motif containing E |
| ITGB4 | integrin, beta 4 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LEPR | leptin receptor |
| LIMK1 | LIM domain kinase 1 |
| LPIN1 | lipin 1 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAP1B | microtubule-associated protein 1B |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| MED25 | mediator complex subunit 25 |
| MST1L | macrophage stimulating 1-like |
| MTMR1 | myotubularin related protein 1 |
| MXD4 | MAX dimerization protein 4 |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NRSN2 | neurensin 2 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OPRM1 | opioid receptor, mu 1 |
| PADI3 | peptidyl arginine deiminase, type III |
| PCDH7 | protocadherin 7 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PGK1 | phosphoglycerate kinase 1 |
| PORCN | porcupine homolog (Drosophila) |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| RAB11B | RAB11B, member RAS oncogene family |
| RASAL2 | RAS protein activator like 2 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RBM5 | RNA binding motif protein 5 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RRBP1 | ribosome binding protein 1 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| STON1 | stonin 1 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TRIM29 | tripartite motif containing 29 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| XAF1 | XIAP associated factor 1 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF235 | zinc finger protein 235 |
| ZNF250 | zinc finger protein 250 |
| ZNF747 | zinc finger protein 747 |
| ZNF804A | zinc finger protein 804A |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| A2M | alpha-2-macroglobulin |
| ACBD4 | acyl-CoA binding domain containing 4 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BAG4 | BCL2-associated athanogene 4 |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BMP15 | bone morphogenetic protein 15 |
| BRSK2 | BR serine/threonine kinase 2 |
| CASS4 | Cas scaffolding protein family member 4 |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CUEDC1 | CUE domain containing 1 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CYP11B1 | cytochrome P450, family 11, subfamily B, polypeptide 1 |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNA2 | DNA replication helicase/nuclease 2 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EGR3 | early growth response 3 |
| FAM110D | family with sequence similarity 110, member D |
| FAM135A | family with sequence similarity 135, member A |
| FAM63B | family with sequence similarity 63, member B |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FGF8 | fibroblast growth factor 8 (androgen-induced) |
| FHL2 | four and a half LIM domains 2 |
| FLNC | filamin C, gamma |
| FOXC1 | forkhead box C1 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GATA4 | GATA binding protein 4 |
| GDPD2 | glycerophosphodiester phosphodiesterase domain containing 2 |
| GEMIN7 | gem (nuclear organelle) associated protein 7 |
| GFI1 | growth factor independent 1 transcription repressor |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GPT | glutamic-pyruvate transaminase (alanine aminotransferase) |
| HS3ST3B1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 |
| HSF4 | heat shock transcription factor 4 |
| HTR1A | 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IER3 | immediate early response 3 |
| IFNA17 | interferon, alpha 17 |
| IFNA21 | interferon, alpha 21 |
| IL13 | interleukin 13 |
| KCNA6 | potassium channel, voltage gated shaker related subfamily A, member 6 |
| KDM8 | lysine (K)-specific demethylase 8 |
| LIM2 | lens intrinsic membrane protein 2, 19kDa |
| LINC00652 | long intergenic non-protein coding RNA 652 |
| LOXL3 | lysyl oxidase-like 3 |
| MBTD1 | mbt domain containing 1 |
| MDM4 | MDM4, p53 regulator |
| MEGF8 | multiple EGF-like-domains 8 |
| MITF | microphthalmia-associated transcription factor |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NPY1R | neuropeptide Y receptor Y1 |
| NRTN | neurturin |
| NXPH3 | neurexophilin 3 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 |
| PCDHB6 | protocadherin beta 6 |
| PDE12 | phosphodiesterase 12 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PGR | progesterone receptor |
| PLG | plasminogen |
| PNPLA2 | patatin-like phospholipase domain containing 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PROL1 | proline rich, lacrimal 1 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PRSS2 | protease, serine, 2 (trypsin 2) |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAI14 | retinoic acid induced 14 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RCL1 | RNA terminal phosphate cyclase-like 1 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 |
| SETD1A | SET domain containing 1A |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SMAD7 | SMAD family member 7 |
| SND1-IT1 | SND1 intronic transcript 1 |
| ST5 | suppression of tumorigenicity 5 |
| STAB2 | stabilin 2 |
| STC2 | stanniocalcin 2 |
| TCP10 | t-complex 10 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TH | tyrosine hydroxylase |
| TMEM8B | transmembrane protein 8B |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TNNI3 | troponin I type 3 (cardiac) |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TYRP1 | tyrosinase-related protein 1 |
| VGF | VGF nerve growth factor inducible |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF205 | zinc finger protein 205 |