fulvestrant-7534 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the fulvestrant-7534 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
ADM adrenomedullin
AKAP7 A kinase (PRKA) anchor protein 7
ALCAM activated leukocyte cell adhesion molecule
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARL15 ADP-ribosylation factor-like 15
ARNT aryl hydrocarbon receptor nuclear translocator
ASCL1 achaete-scute family bHLH transcription factor 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BBS9 Bardet-Biedl syndrome 9
BIRC7 baculoviral IAP repeat containing 7
C17ORF59 chromosome 17 open reading frame 59
C19ORF73 chromosome 19 open reading frame 73
CA5B carbonic anhydrase VB, mitochondrial
CAPN9 calpain 9
CCNG2 cyclin G2
CEP250 centrosomal protein 250kDa
CFAP44 cilia and flagella associated protein 44
CLASP2 cytoplasmic linker associated protein 2
CNTNAP1 contactin associated protein 1
CSNK1G1 casein kinase 1, gamma 1
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNND2 catenin (cadherin-associated protein), delta 2
CYHR1 cysteine/histidine-rich 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DHRS9 dehydrogenase/reductase (SDR family) member 9
DIAPH2 diaphanous-related formin 2
DNAH3 dynein, axonemal, heavy chain 3
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOPEY2 dopey family member 2
DSCR3 Down syndrome critical region 3
DUSP10 dual specificity phosphatase 10
DZIP3 DAZ interacting zinc finger protein 3
EGFR epidermal growth factor receptor
EMID1 EMI domain containing 1
EPHB4 EPH receptor B4
EPS8L1 EPS8-like 1
FBLN1 fibulin 1
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
GJA4 gap junction protein, alpha 4, 37kDa
GK glycerol kinase
GM2A GM2 ganglioside activator
GRB7 growth factor receptor-bound protein 7
GYG2 glycogenin 2
HBEGF heparin-binding EGF-like growth factor
HIST1H2AI histone cluster 1, H2ai
IL17RC interleukin 17 receptor C
IQCE IQ motif containing E
ITGB4 integrin, beta 4
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
LAMP1 lysosomal-associated membrane protein 1
LEPR leptin receptor
LIMK1 LIM domain kinase 1
LPIN1 lipin 1
LRP2 low density lipoprotein receptor-related protein 2
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAP1B microtubule-associated protein 1B
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MCM3AP minichromosome maintenance complex component 3 associated protein
MED25 mediator complex subunit 25
MST1L macrophage stimulating 1-like
MTMR1 myotubularin related protein 1
MXD4 MAX dimerization protein 4
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NFE2L3 nuclear factor, erythroid 2-like 3
NRSN2 neurensin 2
NUMA1 nuclear mitotic apparatus protein 1
OPRM1 opioid receptor, mu 1
PADI3 peptidyl arginine deiminase, type III
PCDH7 protocadherin 7
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PGK1 phosphoglycerate kinase 1
PORCN porcupine homolog (Drosophila)
PPAP2B phosphatidic acid phosphatase type 2B
RAB11B RAB11B, member RAS oncogene family
RASAL2 RAS protein activator like 2
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RBM5 RNA binding motif protein 5
RFTN1 raftlin, lipid raft linker 1
RRBP1 ribosome binding protein 1
SCAPER S-phase cyclin A-associated protein in the ER
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
STON1 stonin 1
TIMP3 TIMP metallopeptidase inhibitor 3
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TRIM29 tripartite motif containing 29
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
XAF1 XIAP associated factor 1
ZFPL1 zinc finger protein-like 1
ZNF235 zinc finger protein 235
ZNF250 zinc finger protein 250
ZNF747 zinc finger protein 747
ZNF804A zinc finger protein 804A

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
A2M alpha-2-macroglobulin
ACBD4 acyl-CoA binding domain containing 4
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BAG4 BCL2-associated athanogene 4
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BMP15 bone morphogenetic protein 15
BRSK2 BR serine/threonine kinase 2
CASS4 Cas scaffolding protein family member 4
CCL19 chemokine (C-C motif) ligand 19
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CLCN2 chloride channel, voltage-sensitive 2
CLTCL1 clathrin, heavy chain-like 1
CPEB1 cytoplasmic polyadenylation element binding protein 1
CUEDC1 CUE domain containing 1
CXCL12 chemokine (C-X-C motif) ligand 12
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
DLK2 delta-like 2 homolog (Drosophila)
DNA2 DNA replication helicase/nuclease 2
DTX2 deltex 2, E3 ubiquitin ligase
EGR3 early growth response 3
FAM110D family with sequence similarity 110, member D
FAM135A family with sequence similarity 135, member A
FAM63B family with sequence similarity 63, member B
FBXL7 F-box and leucine-rich repeat protein 7
FGF8 fibroblast growth factor 8 (androgen-induced)
FHL2 four and a half LIM domains 2
FLNC filamin C, gamma
FOXC1 forkhead box C1
FRAS1 Fraser extracellular matrix complex subunit 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GATA4 GATA binding protein 4
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GEMIN7 gem (nuclear organelle) associated protein 7
GFI1 growth factor independent 1 transcription repressor
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
HS3ST3B1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
HSF4 heat shock transcription factor 4
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IER3 immediate early response 3
IFNA17 interferon, alpha 17
IFNA21 interferon, alpha 21
IL13 interleukin 13
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KDM8 lysine (K)-specific demethylase 8
LIM2 lens intrinsic membrane protein 2, 19kDa
LINC00652 long intergenic non-protein coding RNA 652
LOXL3 lysyl oxidase-like 3
MBTD1 mbt domain containing 1
MDM4 MDM4, p53 regulator
MEGF8 multiple EGF-like-domains 8
MITF microphthalmia-associated transcription factor
MYC v-myc avian myelocytomatosis viral oncogene homolog
NPY1R neuropeptide Y receptor Y1
NRTN neurturin
NXPH3 neurexophilin 3
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR3A3 olfactory receptor, family 3, subfamily A, member 3
PCDHB6 protocadherin beta 6
PDE12 phosphodiesterase 12
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PGR progesterone receptor
PLG plasminogen
PNPLA2 patatin-like phospholipase domain containing 2
POMT2 protein-O-mannosyltransferase 2
PRKG2 protein kinase, cGMP-dependent, type II
PROL1 proline rich, lacrimal 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRSS2 protease, serine, 2 (trypsin 2)
PYCRL pyrroline-5-carboxylate reductase-like
RAI14 retinoic acid induced 14
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RCL1 RNA terminal phosphate cyclase-like 1
SEC14L2 SEC14-like 2 (S. cerevisiae)
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SETD1A SET domain containing 1A
SGK1 serum/glucocorticoid regulated kinase 1
SMAD7 SMAD family member 7
SND1-IT1 SND1 intronic transcript 1
ST5 suppression of tumorigenicity 5
STAB2 stabilin 2
STC2 stanniocalcin 2
TCP10 t-complex 10
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TH tyrosine hydroxylase
TMEM8B transmembrane protein 8B
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNNI3 troponin I type 3 (cardiac)
TRDMT1 tRNA aspartic acid methyltransferase 1
TSKU tsukushi, small leucine rich proteoglycan
TYRP1 tyrosinase-related protein 1
VGF VGF nerve growth factor inducible
ZBTB6 zinc finger and BTB domain containing 6
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF205 zinc finger protein 205