| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the fulvestrant-7539 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AHCYL2 | adenosylhomocysteinase-like 2 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| AMFR | autocrine motility factor receptor, E3 ubiquitin protein ligase |
| ANXA10 | annexin A10 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| BBS7 | Bardet-Biedl syndrome 7 |
| CD68 | CD68 molecule |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CDV3 | CDV3 homolog (mouse) |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 |
| COL5A1 | collagen, type V, alpha 1 |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 |
| DENND3 | DENN/MADD domain containing 3 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DNAJC8 | DnaJ (Hsp40) homolog, subfamily C, member 8 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| FAM155A | family with sequence similarity 155, member A |
| FAM214B | family with sequence similarity 214, member B |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GCAT | glycine C-acetyltransferase |
| GOLGA2 | golgin A2 |
| GRAMD4 | GRAM domain containing 4 |
| GRSF1 | G-rich RNA sequence binding factor 1 |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| H2AFX | H2A histone family, member X |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOMER3 | homer scaffolding protein 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IREB2 | iron-responsive element binding protein 2 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LMF1 | lipase maturation factor 1 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MAPT | microtubule-associated protein tau |
| MED1 | mediator complex subunit 1 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MYLK | myosin light chain kinase |
| NABP1 | nucleic acid binding protein 1 |
| NPC1 | Niemann-Pick disease, type C1 |
| OSR2 | odd-skipped related transciption factor 2 |
| PBLD | phenazine biosynthesis-like protein domain containing |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| PIGO | phosphatidylinositol glycan anchor biosynthesis, class O |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RAB11B | RAB11B, member RAS oncogene family |
| RAD51B | RAD51 paralog B |
| RARG | retinoic acid receptor, gamma |
| RBL2 | retinoblastoma-like 2 |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase |
| RPS9 | ribosomal protein S9 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SEC24D | SEC24 family member D |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPG21 | spastic paraplegia 21 (autosomal recessive, Mast syndrome) |
| ST20 | suppressor of tumorigenicity 20 |
| STK19 | serine/threonine kinase 19 |
| TANK | TRAF family member-associated NFKB activator |
| TBC1D30 | TBC1 domain family, member 30 |
| TPM2 | tropomyosin 2 (beta) |
| TTF2 | transcription termination factor, RNA polymerase II |
| TUBA3C | tubulin, alpha 3c |
| UBOX5 | U-box domain containing 5 |
| USP19 | ubiquitin specific peptidase 19 |
| USP20 | ubiquitin specific peptidase 20 |
| USP48 | ubiquitin specific peptidase 48 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZNF442 | zinc finger protein 442 |
| ZNF468 | zinc finger protein 468 |
| ZNF84 | zinc finger protein 84 |
| Symbol | Name |
|---|---|
| ABCG4 | ATP-binding cassette, sub-family G (WHITE), member 4 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| AGO4 | argonaute RISC catalytic component 4 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ARMC6 | armadillo repeat containing 6 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BTBD18 | BTB (POZ) domain containing 18 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C1S | complement component 1, s subcomponent |
| CD82 | CD82 molecule |
| CDK3 | cyclin-dependent kinase 3 |
| CEP41 | centrosomal protein 41kDa |
| CHRM5 | cholinergic receptor, muscarinic 5 |
| CLDN17 | claudin 17 |
| CLDN7 | claudin 7 |
| CLDN9 | claudin 9 |
| CNTLN | centlein, centrosomal protein |
| COBL | cordon-bleu WH2 repeat protein |
| CRYGC | crystallin, gamma C |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DGKB | diacylglycerol kinase, beta 90kDa |
| DLK2 | delta-like 2 homolog (Drosophila) |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERCC8 | excision repair cross-complementation group 8 |
| ETV6 | ets variant 6 |
| FAM120C | family with sequence similarity 120C |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FRMD8 | FERM domain containing 8 |
| GLB1L | galactosidase, beta 1-like |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HDAC11 | histone deacetylase 11 |
| HIRA | histone cell cycle regulator |
| HIST1H3G | histone cluster 1, H3g |
| HMOX1 | heme oxygenase 1 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HSF2BP | heat shock transcription factor 2 binding protein |
| ID2B | inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene) |
| IGFLR1 | IGF-like family receptor 1 |
| IL22RA1 | interleukin 22 receptor, alpha 1 |
| INO80D | INO80 complex subunit D |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KLHL25 | kelch-like family member 25 |
| KLHL28 | kelch-like family member 28 |
| LMTK2 | lemur tyrosine kinase 2 |
| LRRC17 | leucine rich repeat containing 17 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MOXD1 | monooxygenase, DBH-like 1 |
| MUC3A | mucin 3A, cell surface associated |
| NME5 | NME/NM23 family member 5 |
| NRTN | neurturin |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| OCLM | oculomedin |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OSMR | oncostatin M receptor |
| PDE12 | phosphodiesterase 12 |
| POLR1E | polymerase (RNA) I polypeptide E, 53kDa |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RCL1 | RNA terminal phosphate cyclase-like 1 |
| RIN1 | Ras and Rab interactor 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCAI | suppressor of cancer cell invasion |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SETD6 | SET domain containing 6 |
| SLC30A4 | solute carrier family 30 (zinc transporter), member 4 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| STAB2 | stabilin 2 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
| TCTN2 | tectonic family member 2 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TMEM59L | transmembrane protein 59-like |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TNNT2 | troponin T type 2 (cardiac) |
| TRAIP | TRAF interacting protein |
| TRIM25 | tripartite motif containing 25 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TSPAN31 | tetraspanin 31 |
| UGT8 | UDP glycosyltransferase 8 |
| WDR33 | WD repeat domain 33 |
| ZNF219 | zinc finger protein 219 |
| ZNF35 | zinc finger protein 35 |
| ZNF391 | zinc finger protein 391 |
| ZNF667 | zinc finger protein 667 |
| ZNF668 | zinc finger protein 668 |
| ZNF74 | zinc finger protein 74 |
| ZNF747 | zinc finger protein 747 |