fulvestrant Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
External Link http://ctdbase.org/detail.go?type=chem&acc=C070081
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Genes

158 genes/proteins interacting with the chemical fulvestrant from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AGER advanced glycosylation end product-specific receptor
AGR2 anterior gradient 2
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALPL alkaline phosphatase, liver/bone/kidney
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARID1A AT rich interactive domain 1A (SWI-like)
ARTN artemin
BAD BCL2-associated agonist of cell death
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
C3 complement component 3
CAPN1 calpain 1, (mu/I) large subunit
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CCNA1 cyclin A1
CCNA2 cyclin A2
CCND1 cyclin D1
CDC25B cell division cycle 25B
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CGA glycoprotein hormones, alpha polypeptide
CHEK2 checkpoint kinase 2
CREBBP CREB binding protein
CTSB cathepsin B
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL2 chemokine (C-X-C motif) ligand 2
CYCS cytochrome c, somatic
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DEK DEK proto-oncogene
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ESRRA estrogen-related receptor alpha
F11R F11 receptor
FABP4 fatty acid binding protein 4, adipocyte
FASN fatty acid synthase
FGF2 fibroblast growth factor 2 (basic)
FKBPL FK506 binding protein like
FOXM1 forkhead box M1
FSHB follicle stimulating hormone, beta polypeptide
GCH1 GTP cyclohydrolase 1
GH1 growth hormone 1
GLB1 galactosidase, beta 1
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPER1 G protein-coupled estrogen receptor 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSK3B glycogen synthase kinase 3 beta
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
H2AFX H2A histone family, member X
HMOX1 heme oxygenase 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
ICAM1 intercellular adhesion molecule 1
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2R insulin-like growth factor 2 receptor
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL6 interleukin 6
INSR insulin receptor
IRS1 insulin receptor substrate 1
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KLF4 Kruppel-like factor 4 (gut)
KLK3 kallikrein-related peptidase 3
KRT18 keratin 18, type I
KRT8 keratin 8, type II
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPT microtubule-associated protein tau
MKI67 marker of proliferation Ki-67
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH10 myosin, heavy chain 10, non-muscle
MYOG myogenin (myogenic factor 4)
NCOA1 nuclear receptor coactivator 1
NCOA2 nuclear receptor coactivator 2
NCOA3 nuclear receptor coactivator 3
NCOR1 nuclear receptor corepressor 1
NCOR2 nuclear receptor corepressor 2
NFE2L2 nuclear factor, erythroid 2-like 2
NMNAT1 nicotinamide nucleotide adenylyltransferase 1
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOV nephroblastoma overexpressed
NPPA natriuretic peptide A
NR1I2 nuclear receptor subfamily 1, group I, member 2
OCLN occludin
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PGR progesterone receptor
PLAUR plasminogen activator, urokinase receptor
PLK1 polo-like kinase 1
POMC proopiomelanocortin
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRF1 perforin 1 (pore forming protein)
PRL prolactin
PSEN1 presenilin 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTTG1 pituitary tumor-transforming 1
RB1 retinoblastoma 1
RCOR1 REST corepressor 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
S100G S100 calcium binding protein G
SIN3B SIN3 transcription regulator family member B
SIRT1 sirtuin 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SMAD3 SMAD family member 3
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SOD2 superoxide dismutase 2, mitochondrial
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TACC1 transforming, acidic coiled-coil containing protein 1
TFF1 trefoil factor 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
TIMP2 TIMP metallopeptidase inhibitor 2
TNF tumor necrosis factor
TP53 tumor protein p53
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC22D3 TSC22 domain family, member 3
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
WT1 Wilms tumor 1