fumagillin Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
Description A meroterpenoid resulting from the formal condensation of the hydroxy group of fumagillol with the carboxylic acid group of (all-E)-deca-2,4,6,8-tetraenedioic acid. Originally isolated from the fungus Aspergillus fumigatus, it is used for the control of Nosema infection in honey bees. (Chemical Entities of Biological Interest Ontology, CHEBI_48635)
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Genes

2 genes differentially expressed following the fumagillin small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value

decreased expression

Symbol Name Standardized Value
CD40 CD40 molecule, TNF receptor superfamily member 5 -4.44427
SIRT3 sirtuin 3 -3.2937