furaltadone-3838 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the furaltadone-3838 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ADCK4 aarF domain containing kinase 4
AFF2 AF4/FMR2 family, member 2
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
APLP1 amyloid beta (A4) precursor-like protein 1
ARC activity-regulated cytoskeleton-associated protein
ASCL1 achaete-scute family bHLH transcription factor 1
ATAT1 alpha tubulin acetyltransferase 1
ATN1 atrophin 1
C11ORF16 chromosome 11 open reading frame 16
CFHR4 complement factor H-related 4
CGA glycoprotein hormones, alpha polypeptide
CLCN4 chloride channel, voltage-sensitive 4
CNOT2 CCR4-NOT transcription complex, subunit 2
COL1A1 collagen, type I, alpha 1
COL6A1 collagen, type VI, alpha 1
CTGF connective tissue growth factor
CTIF CBP80/20-dependent translation initiation factor
CTNS cystinosin, lysosomal cystine transporter
CYLD cylindromatosis (turban tumor syndrome)
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYTH4 cytohesin 4
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EZR ezrin
F2 coagulation factor II (thrombin)
FAM171A1 family with sequence similarity 171, member A1
FBLN1 fibulin 1
GPER1 G protein-coupled estrogen receptor 1
HLA-DOA major histocompatibility complex, class II, DO alpha
HOXA11 homeobox A11
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
ICOSLG inducible T-cell co-stimulator ligand
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IFNA5 interferon, alpha 5
IGLV1-44 immunoglobulin lambda variable 1-44
IL2RB interleukin 2 receptor, beta
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KLHL25 kelch-like family member 25
KRT6B keratin 6B, type II
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LTC4S leukotriene C4 synthase
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGEC1 melanoma antigen family C1
MAL mal, T-cell differentiation protein
MC5R melanocortin 5 receptor
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NKX2-5 NK2 homeobox 5
NPTXR neuronal pentraxin receptor
NRDE2 NRDE-2, necessary for RNA interference, domain containing
PBX2 pre-B-cell leukemia homeobox 2
PCYT1B phosphate cytidylyltransferase 1, choline, beta
PHOX2B paired-like homeobox 2b
PICK1 protein interacting with PRKCA 1
PLCH2 phospholipase C, eta 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRDM12 PR domain containing 12
PSG1 pregnancy specific beta-1-glycoprotein 1
PTDSS2 phosphatidylserine synthase 2
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RAD21L1 RAD21-like 1 (S. pombe)
RASAL2 RAS protein activator like 2
RASL11B RAS-like, family 11, member B
RIMS3 regulating synaptic membrane exocytosis 3
RUNDC3A RUN domain containing 3A
SCN4A sodium channel, voltage gated, type IV alpha subunit
SIRT4 sirtuin 4
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC16A4 solute carrier family 16, member 4
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC48A1 solute carrier family 48 (heme transporter), member 1
SPHK2 sphingosine kinase 2
SRSF7 serine/arginine-rich splicing factor 7
SWAP70 SWAP switching B-cell complex 70kDa subunit
TBX10 T-box 10
TBX5 T-box 5
THTPA thiamine triphosphatase
TICAM1 toll-like receptor adaptor molecule 1
TIMP3 TIMP metallopeptidase inhibitor 3
TM4SF4 transmembrane 4 L six family member 4
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNK1 tyrosine kinase, non-receptor, 1
TRIB2 tribbles pseudokinase 2
TRIM10 tripartite motif containing 10
TRIP6 thyroid hormone receptor interactor 6
TTC12 tetratricopeptide repeat domain 12
UBOX5 U-box domain containing 5
WSCD1 WSC domain containing 1

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACTL8 actin-like 8
ADAM15 ADAM metallopeptidase domain 15
ARPIN actin-related protein 2/3 complex inhibitor
ASAP1-IT1 ASAP1 intronic transcript 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCAS1 breast carcinoma amplified sequence 1
BST2 bone marrow stromal cell antigen 2
C19ORF73 chromosome 19 open reading frame 73
C1ORF159 chromosome 1 open reading frame 159
C22ORF46 chromosome 22 open reading frame 46
C4BPA complement component 4 binding protein, alpha
C7ORF43 chromosome 7 open reading frame 43
CARF calcium responsive transcription factor
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC25 coiled-coil domain containing 25
CD83 CD83 molecule
CDK6 cyclin-dependent kinase 6
CHM choroideremia (Rab escort protein 1)
CHRM3 cholinergic receptor, muscarinic 3
CLEC16A C-type lectin domain family 16, member A
CNR2 cannabinoid receptor 2 (macrophage)
DAPK3 death-associated protein kinase 3
DUSP12 dual specificity phosphatase 12
DUSP13 dual specificity phosphatase 13
DUSP2 dual specificity phosphatase 2
EGFL7 EGF-like-domain, multiple 7
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ENOX1 ecto-NOX disulfide-thiol exchanger 1
ERN1 endoplasmic reticulum to nucleus signaling 1
ETNK2 ethanolamine kinase 2
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
GEMIN8 gem (nuclear organelle) associated protein 8
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPNMB glycoprotein (transmembrane) nmb
GPR27 G protein-coupled receptor 27
GRB7 growth factor receptor-bound protein 7
GTF2I general transcription factor IIi
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H4E histone cluster 1, H4e
HP1BP3 heterochromatin protein 1, binding protein 3
IPO8 importin 8
KANSL1L KAT8 regulatory NSL complex subunit 1-like
LAMP3 lysosomal-associated membrane protein 3
LHX6 LIM homeobox 6
LIF leukemia inhibitory factor
LOC729164 hCG1732469
LZTS3 leucine zipper, putative tumor suppressor family member 3
MBNL3 muscleblind-like splicing regulator 3
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL52 mitochondrial ribosomal protein L52
MTCP1 mature T-cell proliferation 1
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MUM1 melanoma associated antigen (mutated) 1
OLFML2A olfactomedin-like 2A
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLXNA3 plexin A3
PRKCE protein kinase C, epsilon
RAB3A RAB3A, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SCML2 sex comb on midleg-like 2 (Drosophila)
SCYL2 SCY1-like 2 (S. cerevisiae)
SDC3 syndecan 3
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
STRN striatin, calmodulin binding protein
SYBU syntabulin (syntaxin-interacting)
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D2 TBC1 domain family, member 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM184C transmembrane protein 184C
TMEM53 transmembrane protein 53
TONSL tonsoku-like, DNA repair protein
TOR4A torsin family 4, member A
TRIM21 tripartite motif containing 21
TRIM25 tripartite motif containing 25
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSPAN5 tetraspanin 5
TWF2 twinfilin actin binding protein 2
VPS9D1 VPS9 domain containing 1
ZNF10 zinc finger protein 10
ZNF227 zinc finger protein 227
ZNF41 zinc finger protein 41
ZNF442 zinc finger protein 442
ZNF480 zinc finger protein 480
ZNF484 zinc finger protein 484
ZNF767P zinc finger family member 767, pseudogene