furaltadone-4313 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the furaltadone-4313 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ADRB3 adrenoceptor beta 3
ANK2 ankyrin 2, neuronal
APCS amyloid P component, serum
ARTN artemin
ASAP1-IT1 ASAP1 intronic transcript 1
AVPR1B arginine vasopressin receptor 1B
B3GAT1 beta-1,3-glucuronyltransferase 1
BAIAP2 BAI1-associated protein 2
BAIAP3 BAI1-associated protein 3
BCL2L1 BCL2-like 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CCDC85B coiled-coil domain containing 85B
CDRT1 CMT1A duplicated region transcript 1
CFHR4 complement factor H-related 4
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CNTNAP2 contactin associated protein-like 2
COL9A2 collagen, type IX, alpha 2
COPE coatomer protein complex, subunit epsilon
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CST4 cystatin S
DCTN2 dynactin 2 (p50)
DGCR8 DGCR8 microprocessor complex subunit
DOK4 docking protein 4
EGFR epidermal growth factor receptor
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAM135A family with sequence similarity 135, member A
FAM65B family with sequence similarity 65, member B
FBXO22 F-box protein 22
FBXO41 F-box protein 41
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GATA4 GATA binding protein 4
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GPER1 G protein-coupled estrogen receptor 1
H2AFX H2A histone family, member X
HCFC1 host cell factor C1
HIST1H4H histone cluster 1, H4h
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HPX hemopexin
HSF1 heat shock transcription factor 1
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
JUND jun D proto-oncogene
KMT2A lysine (K)-specific methyltransferase 2A
KNG1 kininogen 1
LAMA4 laminin, alpha 4
LIME1 Lck interacting transmembrane adaptor 1
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LTBP4 latent transforming growth factor beta binding protein 4
MED25 mediator complex subunit 25
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP3 matrix metallopeptidase 3
MYL4 myosin, light chain 4, alkali; atrial, embryonic
N4BP1 NEDD4 binding protein 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NOP16 NOP16 nucleolar protein
NPPB natriuretic peptide B
NPTX2 neuronal pentraxin II
NUMA1 nuclear mitotic apparatus protein 1
ODAM odontogenic, ameloblast asssociated
PAX2 paired box 2
PBX1 pre-B-cell leukemia homeobox 1
POMT2 protein-O-mannosyltransferase 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRAF2 PRA1 domain family, member 2
PRDM14 PR domain containing 14
PTGIS prostaglandin I2 (prostacyclin) synthase
PVRIG poliovirus receptor related immunoglobulin domain containing
PVT1 Pvt1 oncogene (non-protein coding)
PYY peptide YY
RBM26 RNA binding motif protein 26
RFX2 regulatory factor X, 2 (influences HLA class II expression)
SAMD4A sterile alpha motif domain containing 4A
SAYSD1 SAYSVFN motif domain containing 1
SCN1B sodium channel, voltage gated, type I beta subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SP1 Sp1 transcription factor
SPP1 secreted phosphoprotein 1
SPRR1B small proline-rich protein 1B
SRSF7 serine/arginine-rich splicing factor 7
STC1 stanniocalcin 1
TBC1D30 TBC1 domain family, member 30
TLR1 toll-like receptor 1
TM4SF4 transmembrane 4 L six family member 4
TM4SF5 transmembrane 4 L six family member 5
TMEM259 transmembrane protein 259
TNPO2 transportin 2
TREX1 three prime repair exonuclease 1
TRIM3 tripartite motif containing 3
WDR55 WD repeat domain 55
ZNF235 zinc finger protein 235
ZNF407 zinc finger protein 407
ZNF613 zinc finger protein 613
ZNF639 zinc finger protein 639
ZNF695 zinc finger protein 695

decreased expression

Symbol Name
AFF4 AF4/FMR2 family, member 4
AMDHD2 amidohydrolase domain containing 2
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APOL6 apolipoprotein L, 6
ARHGAP24 Rho GTPase activating protein 24
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAT1 alpha tubulin acetyltransferase 1
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BAHD1 bromo adjacent homology domain containing 1
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C10ORF88 chromosome 10 open reading frame 88
C11ORF30 chromosome 11 open reading frame 30
C17ORF80 chromosome 17 open reading frame 80
C1ORF54 chromosome 1 open reading frame 54
CA9 carbonic anhydrase IX
CCP110 centriolar coiled coil protein 110kDa
CDADC1 cytidine and dCMP deaminase domain containing 1
COL21A1 collagen, type XXI, alpha 1
CTSF cathepsin F
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DNAL4 dynein, axonemal, light chain 4
EFNB1 ephrin-B1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERCC4 excision repair cross-complementation group 4
FAM50B family with sequence similarity 50, member B
FAM53B family with sequence similarity 53, member B
FLCN folliculin
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GRAMD4 GRAM domain containing 4
HIST2H2AA3 histone cluster 2, H2aa3
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOOK1 hook microtubule-tethering protein 1
HOXC11 homeobox C11
IDI2-AS1 IDI2 antisense RNA 1
IFT54 intraflagellar transport 54
IL17RB interleukin 17 receptor B
IPO8 importin 8
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KLF3 Kruppel-like factor 3 (basic)
KPNA5 karyopherin alpha 5 (importin alpha 6)
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIMS2 LIM and senescent cell antigen-like domains 2
LOC257152 uncharacterized LOC257152
LRRC37A3 leucine rich repeat containing 37, member A3
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
MANEA mannosidase, endo-alpha
MAPK12 mitogen-activated protein kinase 12
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MXRA8 matrix-remodelling associated 8
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NKX3-2 NK3 homeobox 2
NPFFR1 neuropeptide FF receptor 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PC pyruvate carboxylase
PDE5A phosphodiesterase 5A, cGMP-specific
PDE8B phosphodiesterase 8B
PECR peroxisomal trans-2-enoyl-CoA reductase
PHLDA3 pleckstrin homology-like domain, family A, member 3
PICK1 protein interacting with PRKCA 1
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
POM121L2 POM121 transmembrane nucleoporin-like 2
PRR15L proline rich 15-like
PRSS53 protease, serine, 53
PTPRH protein tyrosine phosphatase, receptor type, H
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RUNX1-IT1 RUNX1 intronic transcript 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SENP7 SUMO1/sentrin specific peptidase 7
SERGEF secretion regulating guanine nucleotide exchange factor
SETD1A SET domain containing 1A
SLC25A40 solute carrier family 25, member 40
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPAG4 sperm associated antigen 4
STON1 stonin 1
TAGLN transgelin
TBX19 T-box 19
TINAGL1 tubulointerstitial nephritis antigen-like 1
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRAF2 TNF receptor-associated factor 2
TSC22D4 TSC22 domain family, member 4
TTN titin
TUBA4B tubulin, alpha 4b
UNC119 unc-119 homolog (C. elegans)
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VEZT vezatin, adherens junctions transmembrane protein
ZNF286A zinc finger protein 286A
ZNF528 zinc finger protein 528
ZNF529 zinc finger protein 529
ZNF652 zinc finger protein 652
ZNF667 zinc finger protein 667
ZNF711 zinc finger protein 711
ZNF787 zinc finger protein 787