furosemide-3197 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the furosemide-3197 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
AHCYL1 adenosylhomocysteinase-like 1
ANTXR1 anthrax toxin receptor 1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARID4B AT rich interactive domain 4B (RBP1-like)
ARTN artemin
ASIC3 acid sensing (proton gated) ion channel 3
ATF7IP activating transcription factor 7 interacting protein
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BUD31 BUD31 homolog (S. cerevisiae)
C2 complement component 2
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CCDC71 coiled-coil domain containing 71
CCR1 chemokine (C-C motif) receptor 1
CDC14B cell division cycle 14B
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CEMIP cell migration inducing protein, hyaluronan binding
CERS4 ceramide synthase 4
CGA glycoprotein hormones, alpha polypeptide
CHN2 chimerin 2
COL1A2 collagen, type I, alpha 2
COL6A1 collagen, type VI, alpha 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DAPK2 death-associated protein kinase 2
DCTN1 dynactin 1
FER1L4 fer-1-like family member 4, pseudogene (functional)
FH fumarate hydratase
FLNC filamin C, gamma
FSHB follicle stimulating hormone, beta polypeptide
GJA8 gap junction protein, alpha 8, 50kDa
GPSM3 G-protein signaling modulator 3
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HERC2P3 hect domain and RLD 2 pseudogene 3
HLF hepatic leukemia factor
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL1RN interleukin 1 receptor antagonist
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITM2C integral membrane protein 2C
KIAA0040 KIAA0040
KIAA1654 KIAA1654 protein
KIF25 kinesin family member 25
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
KLHL1 kelch-like family member 1
KRIT1 KRIT1, ankyrin repeat containing
KRT9 keratin 9, type I
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAMC2 laminin, gamma 2
LCT lactase
LMF2 lipase maturation factor 2
MAP2K5 mitogen-activated protein kinase kinase 5
MAST2 microtubule associated serine/threonine kinase 2
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MIIP migration and invasion inhibitory protein
MINK1 misshapen-like kinase 1
MOXD1 monooxygenase, DBH-like 1
MRC2 mannose receptor, C type 2
MYOF myoferlin
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
OPCML opioid binding protein/cell adhesion molecule-like
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PDE4A phosphodiesterase 4A, cAMP-specific
PER1 period circadian clock 1
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHS1 pleckstrin homology domain containing, family S member 1
PRDM1 PR domain containing 1, with ZNF domain
PRKG2 protein kinase, cGMP-dependent, type II
PSD4 pleckstrin and Sec7 domain containing 4
RASAL2 RAS protein activator like 2
RUNX1 runt-related transcription factor 1
RUSC2 RUN and SH3 domain containing 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPPL2B signal peptide peptidase like 2B
STOM stomatin
STRA6 stimulated by retinoic acid 6
TAPBP TAP binding protein (tapasin)
TAT tyrosine aminotransferase
TBX1 T-box 1
TDRD12 tudor domain containing 12
THBD thrombomodulin
TNC tenascin C
TPM2 tropomyosin 2 (beta)
UBE2B ubiquitin-conjugating enzyme E2B
VPREB3 pre-B lymphocyte 3
WDR4 WD repeat domain 4
WSB1 WD repeat and SOCS box containing 1
ZCCHC11 zinc finger, CCHC domain containing 11
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF384 zinc finger protein 384
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACAD10 acyl-CoA dehydrogenase family, member 10
ACTG2 actin, gamma 2, smooth muscle, enteric
ADRA2C adrenoceptor alpha 2C
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
C11ORF30 chromosome 11 open reading frame 30
C14ORF93 chromosome 14 open reading frame 93
C2ORF27A chromosome 2 open reading frame 27A
CAMKV CaM kinase-like vesicle-associated
CAPN15 calpain 15
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CD53 CD53 molecule
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCN5 chloride channel, voltage-sensitive 5
CLCN6 chloride channel, voltage-sensitive 6
CLDN15 claudin 15
CLIP4 CAP-GLY domain containing linker protein family, member 4
CSTA cystatin A (stefin A)
CTNNBIP1 catenin, beta interacting protein 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DMTN dematin actin binding protein
DNAH17 dynein, axonemal, heavy chain 17
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPY19L1P1 DPY19L1 pseudogene 1
DYSF dysferlin
ENO3 enolase 3 (beta, muscle)
FBXO4 F-box protein 4
FLT4 fms-related tyrosine kinase 4
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GAMT guanidinoacetate N-methyltransferase
GLI3 GLI family zinc finger 3
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPX1 glutathione peroxidase 1
HCFC1 host cell factor C1
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HOXC10 homeobox C10
HOXC8 homeobox C8
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
INHA inhibin, alpha
ITGA10 integrin, alpha 10
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
JUNB jun B proto-oncogene
KLF2 Kruppel-like factor 2
LAMA3 laminin, alpha 3
LDHB lactate dehydrogenase B
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRRC37A3 leucine rich repeat containing 37, member A3
LYZ lysozyme
MAST3 microtubule associated serine/threonine kinase 3
MBOAT2 membrane bound O-acyltransferase domain containing 2
MMRN2 multimerin 2
MPO myeloperoxidase
MYO1E myosin IE
NAT6 N-acetyltransferase 6 (GCN5-related)
NDOR1 NADPH dependent diflavin oxidoreductase 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NIPAL2 NIPA-like domain containing 2
NPIPB3 nuclear pore complex interacting protein family, member B3
OVGP1 oviductal glycoprotein 1, 120kDa
PC pyruvate carboxylase
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PSAT1 phosphoserine aminotransferase 1
PTDSS2 phosphatidylserine synthase 2
REM1 RAS (RAD and GEM)-like GTP-binding 1
RNF122 ring finger protein 122
SAA4 serum amyloid A4, constitutive
SFXN3 sideroflexin 3
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SPRY2 sprouty homolog 2 (Drosophila)
SRD5A3 steroid 5 alpha-reductase 3
SREK1IP1 SREK1-interacting protein 1
SRGN serglycin
STX1A syntaxin 1A (brain)
TAOK1 TAO kinase 1
TCP10 t-complex 10
TMEM120B transmembrane protein 120B
TMEM212 transmembrane protein 212
TSC22D4 TSC22 domain family, member 4
UPK3B uroplakin 3B
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
XK X-linked Kx blood group
ZBTB44 zinc finger and BTB domain containing 44
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF219 zinc finger protein 219
ZNF35 zinc finger protein 35
ZNF365 zinc finger protein 365
ZNF821 zinc finger protein 821