| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the furosemide-6841 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACO2 | aconitase 2, mitochondrial |
| AFF2 | AF4/FMR2 family, member 2 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ALDOB | aldolase B, fructose-bisphosphate |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| APOE | apolipoprotein E |
| APOM | apolipoprotein M |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATN1 | atrophin 1 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| C21ORF2 | chromosome 21 open reading frame 2 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CALB1 | calbindin 1, 28kDa |
| CCDC134 | coiled-coil domain containing 134 |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CHAT | choline O-acetyltransferase |
| CLGN | calmegin |
| CPNE7 | copine VII |
| CTSF | cathepsin F |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DOCK6 | dedicator of cytokinesis 6 |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| ELL | elongation factor RNA polymerase II |
| EPHB2 | EPH receptor B2 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 |
| EXOSC2 | exosome component 2 |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FOLH1B | folate hydrolase 1B |
| GJC2 | gap junction protein, gamma 2, 47kDa |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPR25 | G protein-coupled receptor 25 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GYPB | glycophorin B (MNS blood group) |
| HLA-DRB4 | major histocompatibility complex, class II, DR beta 4 |
| HSPG2 | heparan sulfate proteoglycan 2 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| ING2 | inhibitor of growth family, member 2 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KIF21B | kinesin family member 21B |
| KLF8 | Kruppel-like factor 8 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LAT2 | linker for activation of T cells family, member 2 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| PAX2 | paired box 2 |
| PCNX | pecanex homolog (Drosophila) |
| PENK | proenkephalin |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PLK3 | polo-like kinase 3 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PVRL3 | poliovirus receptor-related 3 |
| RAB3B | RAB3B, member RAS oncogene family |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF208 | ring finger protein 208 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAA3P | serum amyloid A3 pseudogene |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMAD6 | SMAD family member 6 |
| SPAG8 | sperm associated antigen 8 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 |
| TAT | tyrosine aminotransferase |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TFF2 | trefoil factor 2 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TRMT44 | tRNA methyltransferase 44 homolog (S. cerevisiae) |
| TUBA3C | tubulin, alpha 3c |
| TUBA4B | tubulin, alpha 4b |
| UBA7 | ubiquitin-like modifier activating enzyme 7 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| VWA5A | von Willebrand factor A domain containing 5A |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) |
| AUTS2 | autism susceptibility candidate 2 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BIRC7 | baculoviral IAP repeat containing 7 |
| C11ORF57 | chromosome 11 open reading frame 57 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CAPRIN2 | caprin family member 2 |
| CCDC25 | coiled-coil domain containing 25 |
| CCNT1 | cyclin T1 |
| CHM | choroideremia (Rab escort protein 1) |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| CORT | cortistatin |
| DEAF1 | DEAF1 transcription factor |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| ERO1L | ERO1-like (S. cerevisiae) |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM111A | family with sequence similarity 111, member A |
| FAM131A | family with sequence similarity 131, member A |
| FANCE | Fanconi anemia, complementation group E |
| FLCN | folliculin |
| GAN | gigaxonin |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPX2 | glutathione peroxidase 2 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC11 | histone deacetylase 11 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HOXC8 | homeobox C8 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HPN | hepsin |
| ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IQCG | IQ motif containing G |
| KLF2 | Kruppel-like factor 2 |
| KLHL25 | kelch-like family member 25 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRT15 | keratin 15, type I |
| KRT16 | keratin 16, type I |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LHX6 | LIM homeobox 6 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LIN37 | lin-37 DREAM MuvB core complex component |
| LINS | lines homolog (Drosophila) |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NEK11 | NIMA-related kinase 11 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PARD6B | par-6 family cell polarity regulator beta |
| PGPEP1 | pyroglutamyl-peptidase I |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRPH | peripherin |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RFXAP | regulatory factor X-associated protein |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RRAGB | Ras-related GTP binding B |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SIK1 | salt-inducible kinase 1 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SMIM14 | small integral membrane protein 14 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| STRN | striatin, calmodulin binding protein |
| TBC1D19 | TBC1 domain family, member 19 |
| TMEM53 | transmembrane protein 53 |
| TRIM21 | tripartite motif containing 21 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF136 | zinc finger protein 136 |
| ZNF16 | zinc finger protein 16 |
| ZNF516 | zinc finger protein 516 |
| ZNF747 | zinc finger protein 747 |
| ZNF770 | zinc finger protein 770 |
