fursultiamine-2929 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the fursultiamine-2929 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ALDOB aldolase B, fructose-bisphosphate
ANO2 anoctamin 2, calcium activated chloride channel
APOC1 apolipoprotein C-I
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
AVPR1B arginine vasopressin receptor 1B
C11ORF16 chromosome 11 open reading frame 16
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CARD10 caspase recruitment domain family, member 10
CAV2 caveolin 2
CCDC134 coiled-coil domain containing 134
CCDC92 coiled-coil domain containing 92
CDC5L cell division cycle 5-like
CECR1 cat eye syndrome chromosome region, candidate 1
CLDN11 claudin 11
CLTA clathrin, light chain A
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CST2 cystatin SA
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DLC1 DLC1 Rho GTPase activating protein
ELSPBP1 epididymal sperm binding protein 1
EPHB3 EPH receptor B3
EPN2 epsin 2
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GLRA1 glycine receptor, alpha 1
GSK3A glycogen synthase kinase 3 alpha
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMG20B high mobility group 20B
HOXA11 homeobox A11
HRASLS2 HRAS-like suppressor 2
IFNA14 interferon, alpha 14
IGFBP5 insulin-like growth factor binding protein 5
IL1RN interleukin 1 receptor antagonist
IL22 interleukin 22
IL27RA interleukin 27 receptor, alpha
INSL5 insulin-like 5
KRT8 keratin 8, type II
LENEP lens epithelial protein
LHFP lipoma HMGIC fusion partner
MAP4 microtubule-associated protein 4
MT4 metallothionein 4
NF2 neurofibromin 2 (merlin)
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NINJ2 ninjurin 2
NNAT neuronatin
NPTX2 neuronal pentraxin II
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OGFR opioid growth factor receptor
OLFML2A olfactomedin-like 2A
OR10H1 olfactory receptor, family 10, subfamily H, member 1
PCBP4 poly(rC) binding protein 4
PKP3 plakophilin 3
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAC4 placenta-specific 4
PMEL premelanosome protein
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRDM1 PR domain containing 1, with ZNF domain
PRELP proline/arginine-rich end leucine-rich repeat protein
PRF1 perforin 1 (pore forming protein)
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
RAB40B RAB40B, member RAS oncogene family
RAP1GAP2 RAP1 GTPase activating protein 2
RBM17 RNA binding motif protein 17
REPS2 RALBP1 associated Eps domain containing 2
RGS10 regulator of G-protein signaling 10
RGS5 regulator of G-protein signaling 5
RPS11 ribosomal protein S11
SCARF1 scavenger receptor class F, member 1
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SIN3B SIN3 transcription regulator family member B
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLIT1 slit homolog 1 (Drosophila)
SLN sarcolipin
SORBS3 sorbin and SH3 domain containing 3
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STYK1 serine/threonine/tyrosine kinase 1
SYN2 synapsin II
TBXA2R thromboxane A2 receptor
TEX40 testis expressed 40
TGM2 transglutaminase 2
THBS1 thrombospondin 1
TJP1 tight junction protein 1
TONSL tonsoku-like, DNA repair protein
TRAF1 TNF receptor-associated factor 1
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TSC2 tuberous sclerosis 2
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VIPR2 vasoactive intestinal peptide receptor 2
VWF von Willebrand factor
WIZ widely interspaced zinc finger motifs
WNT16 wingless-type MMTV integration site family, member 16
XYLB xylulokinase homolog (H. influenzae)
ZC3H13 zinc finger CCCH-type containing 13
ZNF177 zinc finger protein 177

decreased expression

Symbol Name
AES amino-terminal enhancer of split
AHCTF1 AT hook containing transcription factor 1
AOAH acyloxyacyl hydrolase (neutrophil)
ARF5 ADP-ribosylation factor 5
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARID4A AT rich interactive domain 4A (RBP1-like)
ARMC7 armadillo repeat containing 7
ARRB1 arrestin, beta 1
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C22ORF29 chromosome 22 open reading frame 29
CAAP1 caspase activity and apoptosis inhibitor 1
CBY1 chibby homolog 1 (Drosophila)
CCDC88C coiled-coil domain containing 88C
CHKB choline kinase beta
COX7A2L cytochrome c oxidase subunit VIIa polypeptide 2 like
CSNK1G3 casein kinase 1, gamma 3
CYBRD1 cytochrome b reductase 1
DHDDS dehydrodolichyl diphosphate synthase
DOLK dolichol kinase
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
EGR2 early growth response 2
ENAH enabled homolog (Drosophila)
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FADD Fas (TNFRSF6)-associated via death domain
FAM188A family with sequence similarity 188, member A
FAM8A1 family with sequence similarity 8, member A1
FNBP1L formin binding protein 1-like
GEMIN6 gem (nuclear organelle) associated protein 6
GJA1 gap junction protein, alpha 1, 43kDa
GK3P glycerol kinase 3 pseudogene
GPR63 G protein-coupled receptor 63
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
GSTM3 glutathione S-transferase mu 3 (brain)
GUSBP3 glucuronidase, beta pseudogene 3
HCAR3 hydroxycarboxylic acid receptor 3
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10
IP6K1 inositol hexakisphosphate kinase 1
IRAK4 interleukin-1 receptor-associated kinase 4
LINC00115 long intergenic non-protein coding RNA 115
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MCM9 minichromosome maintenance complex component 9
MCOLN1 mucolipin 1
MDM4 MDM4, p53 regulator
MPDU1 mannose-P-dolichol utilization defect 1
MTG1 mitochondrial ribosome-associated GTPase 1
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
PANX1 pannexin 1
PDZD7 PDZ domain containing 7
PECR peroxisomal trans-2-enoyl-CoA reductase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PKN1 protein kinase N1
PLA2G12A phospholipase A2, group XIIA
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
POLM polymerase (DNA directed), mu
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
QTRT1 queuine tRNA-ribosyltransferase 1
RAB8B RAB8B, member RAS oncogene family
RBM41 RNA binding motif protein 41
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RINT1 RAD50 interactor 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
SLC25A40 solute carrier family 25, member 40
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5
SLC38A6 solute carrier family 38, member 6
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit
TBCCD1 TBCC domain containing 1
THAP1 THAP domain containing, apoptosis associated protein 1
THAP10 THAP domain containing 10
THOP1 thimet oligopeptidase 1
TLR6 toll-like receptor 6
TMEM134 transmembrane protein 134
TMEM209 transmembrane protein 209
TMEM260 transmembrane protein 260
TMOD3 tropomodulin 3 (ubiquitous)
TRIM9 tripartite motif containing 9
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TROAP trophinin associated protein
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TSC22D1 TSC22 domain family, member 1
TSPYL2 TSPY-like 2
TTC26 tetratricopeptide repeat domain 26
TTC33 tetratricopeptide repeat domain 33
UPP1 uridine phosphorylase 1
USP32 ubiquitin specific peptidase 32
VCPKMT valosin containing protein lysine (K) methyltransferase
VILL villin-like
VPS54 vacuolar protein sorting 54 homolog (S. cerevisiae)
ZNF302 zinc finger protein 302
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF468 zinc finger protein 468
ZNF770 zinc finger protein 770
ZNF813 zinc finger protein 813