fursultiamine-4975 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the fursultiamine-4975 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
AMPD3 adenosine monophosphate deaminase 3
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARC activity-regulated cytoskeleton-associated protein
ARHGAP33 Rho GTPase activating protein 33
ASPH aspartate beta-hydroxylase
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
AUTS2 autism susceptibility candidate 2
BGLAP bone gamma-carboxyglutamate (gla) protein
BGN biglycan
BIRC7 baculoviral IAP repeat containing 7
BMP4 bone morphogenetic protein 4
BMP5 bone morphogenetic protein 5
CACYBP calcyclin binding protein
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC85C coiled-coil domain containing 85C
CD248 CD248 molecule, endosialin
CD4 CD4 molecule
CD58 CD58 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CEP112 centrosomal protein 112kDa
CHD5 chromodomain helicase DNA binding protein 5
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal)
CLCN7 chloride channel, voltage-sensitive 7
CLGN calmegin
CLIC2 chloride intracellular channel 2
CNTFR ciliary neurotrophic factor receptor
DIO2 deiodinase, iodothyronine, type II
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
EDA ectodysplasin A
EPHA1 EPH receptor A1
ESR1 estrogen receptor 1
F13A1 coagulation factor XIII, A1 polypeptide
FAM205BP transmembrane protein C9orf144B pseudogene
FBN2 fibrillin 2
FBXO41 F-box protein 41
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FKBP10 FK506 binding protein 10, 65 kDa
GLRX glutaredoxin (thioltransferase)
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNRH2 gonadotropin-releasing hormone 2
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPR27 G protein-coupled receptor 27
GRAMD1C GRAM domain containing 1C
GSPT1 G1 to S phase transition 1
GYG2 glycogenin 2
HCRP1 hepatocellular carcinoma-related HCRP1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IL1RAP interleukin 1 receptor accessory protein
INHBA inhibin, beta A
KRT19P2 keratin 19 pseudogene 2
LIG3 ligase III, DNA, ATP-dependent
MAP2K5 mitogen-activated protein kinase kinase 5
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MARK2 MAP/microtubule affinity-regulating kinase 2
MBD2 methyl-CpG binding domain protein 2
MR1 major histocompatibility complex, class I-related
MTCP1 mature T-cell proliferation 1
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NCF2 neutrophil cytosolic factor 2
NDRG2 NDRG family member 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR5A2 nuclear receptor subfamily 5, group A, member 2
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
POPDC3 popeye domain containing 3
POU2F2 POU class 2 homeobox 2
PPP1R37 protein phosphatase 1, regulatory subunit 37
PRDX2 peroxiredoxin 2
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PVR poliovirus receptor
QSER1 glutamine and serine rich 1
RAB36 RAB36, member RAS oncogene family
RHEB Ras homolog enriched in brain
SAYSD1 SAYSVFN motif domain containing 1
SCAND2P SCAN domain containing 2 pseudogene
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SIRT5 sirtuin 5
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STAT5A signal transducer and activator of transcription 5A
TAS2R7 taste receptor, type 2, member 7
TBL1Y transducin (beta)-like 1, Y-linked
TDO2 tryptophan 2,3-dioxygenase
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM19 transmembrane protein 19
TNIK TRAF2 and NCK interacting kinase
USP19 ubiquitin specific peptidase 19
VAMP5 vesicle-associated membrane protein 5
XAF1 XIAP associated factor 1
ZBTB22 zinc finger and BTB domain containing 22
ZC2HC1C zinc finger, C2HC-type containing 1C
ZNF112 zinc finger protein 112
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL15 ADP-ribosylation factor-like 15
BAHCC1 BAH domain and coiled-coil containing 1
C11ORF80 chromosome 11 open reading frame 80
C14ORF93 chromosome 14 open reading frame 93
C1ORF105 chromosome 1 open reading frame 105
C5ORF45 chromosome 5 open reading frame 45
CA11 carbonic anhydrase XI
CCDC170 coiled-coil domain containing 170
CCDC186 coiled-coil domain containing 186
CCDC94 coiled-coil domain containing 94
CDK3 cyclin-dependent kinase 3
CEP97 centrosomal protein 97kDa
CGREF1 cell growth regulator with EF-hand domain 1
CHST10 carbohydrate sulfotransferase 10
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLCF1 cardiotrophin-like cytokine factor 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
DYSF dysferlin
ENO2 enolase 2 (gamma, neuronal)
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FILIP1L filamin A interacting protein 1-like
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GEMIN8 gem (nuclear organelle) associated protein 8
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPATCH2L G patch domain containing 2-like
GPR19 G protein-coupled receptor 19
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2BJ histone cluster 1, H2bj
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGFLR1 IGF-like family receptor 1
KAT2A K(lysine) acetyltransferase 2A
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0754 KIAA0754
KLF3 Kruppel-like factor 3 (basic)
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LMCD1 LIM and cysteine-rich domains 1
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
MED15 mediator complex subunit 15
NIPAL2 NIPA-like domain containing 2
NRGN neurogranin (protein kinase C substrate, RC3)
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PEX26 peroxisomal biogenesis factor 26
PHEX phosphate regulating endopeptidase homolog, X-linked
PLA2G3 phospholipase A2, group III
PLD3 phospholipase D family, member 3
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PMCH pro-melanin-concentrating hormone
POM121 POM121 transmembrane nucleoporin
PRODH proline dehydrogenase (oxidase) 1
RAB3A RAB3A, member RAS oncogene family
RASAL1 RAS protein activator like 1 (GAP1 like)
RBM41 RNA binding motif protein 41
RCAN3 RCAN family member 3
RGS2 regulator of G-protein signaling 2
RIN2 Ras and Rab interactor 2
RPAP1 RNA polymerase II associated protein 1
RPAP2 RNA polymerase II associated protein 2
RPGRIP1L RPGRIP1-like
RUFY2 RUN and FYVE domain containing 2
SCAI suppressor of cancer cell invasion
SCGB2A2 secretoglobin, family 2A, member 2
SETD1A SET domain containing 1A
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SUGP1 SURP and G patch domain containing 1
SYBU syntabulin (syntaxin-interacting)
THBS3 thrombospondin 3
TMC5 transmembrane channel-like 5
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
ULBP2 UL16 binding protein 2
UPK3B uroplakin 3B
USB1 U6 snRNA biogenesis 1
VAX2 ventral anterior homeobox 2
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WFDC2 WAP four-disulfide core domain 2
XK X-linked Kx blood group
XYLT2 xylosyltransferase II
ZBTB48 zinc finger and BTB domain containing 48
ZNF136 zinc finger protein 136
ZNF204P zinc finger protein 204, pseudogene
ZNF254 zinc finger protein 254
ZNF37BP zinc finger protein 37B, pseudogene
ZNF574 zinc finger protein 574