fursultiamine-6630 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the fursultiamine-6630 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADGRA2 adhesion G protein-coupled receptor A2
ADRBK2 adrenergic, beta, receptor kinase 2
AKAP8L A kinase (PRKA) anchor protein 8-like
AMPH amphiphysin
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATF7IP activating transcription factor 7 interacting protein
ATXN7L1 ataxin 7-like 1
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BCL2 B-cell CLL/lymphoma 2
BICD1 bicaudal D homolog 1 (Drosophila)
BTG2 BTG family, member 2
C17ORF59 chromosome 17 open reading frame 59
CCDC9 coiled-coil domain containing 9
CEP295 centrosomal protein 295kDa
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
COL1A1 collagen, type I, alpha 1
CST4 cystatin S
DHODH dihydroorotate dehydrogenase (quinone)
DNM3 dynamin 3
DTNA dystrobrevin, alpha
EGR4 early growth response 4
EYA3 EYA transcriptional coactivator and phosphatase 3
FABP7 fatty acid binding protein 7, brain
FAM76A family with sequence similarity 76, member A
FILIP1L filamin A interacting protein 1-like
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FOXF1 forkhead box F1
FPR1 formyl peptide receptor 1
GLB1L galactosidase, beta 1-like
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
HABP4 hyaluronan binding protein 4
HGD homogentisate 1,2-dioxygenase
HIP1 huntingtin interacting protein 1
HIST1H3I histone cluster 1, H3i
HLA-DOA major histocompatibility complex, class II, DO alpha
ID2B inhibitor of DNA binding 2B, dominant negative helix-loop-helix protein (pseudogene)
IDS iduronate 2-sulfatase
IL16 interleukin 16
ING1 inhibitor of growth family, member 1
ING2 inhibitor of growth family, member 2
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM8 lysine (K)-specific demethylase 8
KIAA0040 KIAA0040
KLF3 Kruppel-like factor 3 (basic)
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LOC390998 ribosomal protein L10 pseudogene
LRRC48 leucine rich repeat containing 48
LRRN2 leucine rich repeat neuronal 2
MAP2K5 mitogen-activated protein kinase kinase 5
MAX MYC associated factor X
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MGC2889 uncharacterized protein MGC2889
MMP3 matrix metallopeptidase 3
MUC6 mucin 6, oligomeric mucus/gel-forming
NCF4 neutrophil cytosolic factor 4, 40kDa
NMT2 N-myristoyltransferase 2
NPAS1 neuronal PAS domain protein 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PRL prolactin
RND1 Rho family GTPase 1
RPL35A ribosomal protein L35a
RUNDC3A RUN domain containing 3A
RUNX1 runt-related transcription factor 1
RYR2 ryanodine receptor 2 (cardiac)
SBNO1 strawberry notch homolog 1 (Drosophila)
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SH2D3A SH2 domain containing 3A
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SPIDR scaffolding protein involved in DNA repair
SRSF7 serine/arginine-rich splicing factor 7
STATH statherin
TBCD tubulin folding cofactor D
TCP10 t-complex 10
TGM2 transglutaminase 2
THOC5 THO complex 5
TLE4 transducin-like enhancer of split 4
TOP3B topoisomerase (DNA) III beta
TPM1 tropomyosin 1 (alpha)
TRA T cell receptor alpha locus
TRIM10 tripartite motif containing 10
TRIM29 tripartite motif containing 29
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VAV2 vav 2 guanine nucleotide exchange factor
VNN2 vanin 2
VRTN vertebrae development associated
ZCCHC14 zinc finger, CCHC domain containing 14
ZNF24 zinc finger protein 24
ZNF280B zinc finger protein 280B
ZNF518A zinc finger protein 518A
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARL14 ADP-ribosylation factor-like 14
ARMCX4 armadillo repeat containing, X-linked 4
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAHCC1 BAH domain and coiled-coil containing 1
BBS7 Bardet-Biedl syndrome 7
BOLA1 bolA family member 1
C1R complement component 1, r subcomponent
C5ORF42 chromosome 5 open reading frame 42
CA5BP1 carbonic anhydrase VB pseudogene 1
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CAMKMT calmodulin-lysine N-methyltransferase
CAPN15 calpain 15
CCDC85C coiled-coil domain containing 85C
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CHM choroideremia (Rab escort protein 1)
CLDN1 claudin 1
CLDN14 claudin 14
CNN2 calponin 2
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTAGE9 CTAGE family, member 9
CYBRD1 cytochrome b reductase 1
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DBF4B DBF4 zinc finger B
DDN dendrin
DEAF1 DEAF1 transcription factor
ELOVL4 ELOVL fatty acid elongase 4
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FMO4 flavin containing monooxygenase 4
FRS3 fibroblast growth factor receptor substrate 3
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GLS2 glutaminase 2 (liver, mitochondrial)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HAMP hepcidin antimicrobial peptide
HLA-DMA major histocompatibility complex, class II, DM alpha
HLX H2.0-like homeobox
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HSPA1L heat shock 70kDa protein 1-like
IL15RA interleukin 15 receptor, alpha
IL4R interleukin 4 receptor
KRT6A keratin 6A, type II
LAMC3 laminin, gamma 3
LMCD1 LIM and cysteine-rich domains 1
LNPEP leucyl/cystinyl aminopeptidase
MDFI MyoD family inhibitor
MDM4 MDM4, p53 regulator
MKNK1 MAP kinase interacting serine/threonine kinase 1
MTA2 metastasis associated 1 family, member 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NINJ1 ninjurin 1
NPM3 nucleophosmin/nucleoplasmin 3
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PADI1 peptidyl arginine deiminase, type I
PAIP2B poly(A) binding protein interacting protein 2B
PICK1 protein interacting with PRKCA 1
PID1 phosphotyrosine interaction domain containing 1
PLD2 phospholipase D2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PRSS8 protease, serine, 8
RAP1GAP2 RAP1 GTPase activating protein 2
REM1 RAS (RAD and GEM)-like GTP-binding 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SEPP1 selenoprotein P, plasma, 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SH2D2A SH2 domain containing 2A
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLITRK5 SLIT and NTRK-like family, member 5
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
STAG3 stromal antigen 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD5 StAR-related lipid transfer (START) domain containing 5
STK16 serine/threonine kinase 16
TBC1D19 TBC1 domain family, member 19
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM121 transmembrane protein 121
TMEM212 transmembrane protein 212
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRABD TraB domain containing
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TXK TXK tyrosine kinase
UBQLN4 ubiquilin 4
VNN1 vanin 1
WDR25 WD repeat domain 25
WDR41 WD repeat domain 41
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
YOD1 YOD1 deubiquitinase
ZNF141 zinc finger protein 141
ZNF286A zinc finger protein 286A
ZNF510 zinc finger protein 510
ZNF549 zinc finger protein 549
ZNF747 zinc finger protein 747