fusidic acid-1293 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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200 genes differentially expressed following the fusidic acid-1293 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ADAM10 ADAM metallopeptidase domain 10
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APAF1 apoptotic peptidase activating factor 1
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARL1 ADP-ribosylation factor-like 1
ARL4C ADP-ribosylation factor-like 4C
ATP13A3 ATPase type 13A3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CALU calumenin
CCNG2 cyclin G2
CDK6 cyclin-dependent kinase 6
CDV3 CDV3 homolog (mouse)
CLEC4A C-type lectin domain family 4, member A
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
COL4A2 collagen, type IV, alpha 2
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CUL4B cullin 4B
CYB5B cytochrome b5 type B (outer mitochondrial membrane)
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DIAPH2-AS1 DIAPH2 antisense RNA 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DVL2 dishevelled segment polarity protein 2
ELAVL1 ELAV like RNA binding protein 1
EML3 echinoderm microtubule associated protein like 3
FAM188A family with sequence similarity 188, member A
FBXW11 F-box and WD repeat domain containing 11
FCF1 FCF1 rRNA-processing protein
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FLJ10038 uncharacterized protein FLJ10038
FRY furry homolog (Drosophila)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GTF2I general transcription factor IIi
HCRP1 hepatocellular carcinoma-related HCRP1
HIPK3 homeodomain interacting protein kinase 3
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IL1RAP interleukin 1 receptor accessory protein
ING4 inhibitor of growth family, member 4
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KIAA0754 KIAA0754
KLHL28 kelch-like family member 28
LHFP lipoma HMGIC fusion partner
LMAN1 lectin, mannose-binding, 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAX MYC associated factor X
MCL1 myeloid cell leukemia 1
MFN2 mitofusin 2
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NET1 neuroepithelial cell transforming 1
NIPBL Nipped-B homolog (Drosophila)
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NOTCH2 notch 2
NRP1 neuropilin 1
PAPOLA poly(A) polymerase alpha
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLSCR3 phospholipid scramblase 3
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
RAB6A RAB6A, member RAS oncogene family
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCYL2 SCY1-like 2 (S. cerevisiae)
SIRT5 sirtuin 5
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SNAP23 synaptosomal-associated protein, 23kDa
SP100 SP100 nuclear antigen
SPAST spastin
SRSF1 serine/arginine-rich splicing factor 1
SS18 synovial sarcoma translocation, chromosome 18
SSBP3 single stranded DNA binding protein 3
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STK17B serine/threonine kinase 17b
STOM stomatin
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TMPO thymopoietin
TRIM25 tripartite motif containing 25
TTC38 tetratricopeptide repeat domain 38
UNC45A unc-45 homolog A (C. elegans)
UTRN utrophin
WDR91 WD repeat domain 91
WEE1 WEE1 G2 checkpoint kinase
WSB1 WD repeat and SOCS box containing 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZBED8 zinc finger, BED-type containing 8
ZMYND11 zinc finger, MYND-type containing 11
ZNF22 zinc finger protein 22
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BBS7 Bardet-Biedl syndrome 7
BCORL1 BCL6 corepressor-like 1
BRMS1 breast cancer metastasis suppressor 1
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C1ORF159 chromosome 1 open reading frame 159
CAPN15 calpain 15
CEP170B centrosomal protein 170B
CHMP7 charged multivesicular body protein 7
CIC capicua transcriptional repressor
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CPPED1 calcineurin-like phosphoesterase domain containing 1
CREB3 cAMP responsive element binding protein 3
CTNNBIP1 catenin, beta interacting protein 1
DBF4B DBF4 zinc finger B
DPY19L2P2 DPY19L2 pseudogene 2
DUSP8 dual specificity phosphatase 8
DYSF dysferlin
EDC4 enhancer of mRNA decapping 4
ERAP2 endoplasmic reticulum aminopeptidase 2
ERCC2 excision repair cross-complementation group 2
FAM222B family with sequence similarity 222, member B
FAM53B family with sequence similarity 53, member B
FHOD1 formin homology 2 domain containing 1
FMNL1 formin-like 1
GALK1 galactokinase 1
GATAD2A GATA zinc finger domain containing 2A
GGTLC1 gamma-glutamyltransferase light chain 1
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2AG histone cluster 1, H2ag
IGFLR1 IGF-like family receptor 1
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IPO4 importin 4
IRX5 iroquois homeobox 5
ITPKC inositol-trisphosphate 3-kinase C
KIAA0556 KIAA0556
KLHL21 kelch-like family member 21
KRI1 KRI1 homolog (S. cerevisiae)
L2HGDH L-2-hydroxyglutarate dehydrogenase
LPPR2 lipid phosphate phosphatase-related protein type 2
LRRK1 leucine-rich repeat kinase 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBTD1 mbt domain containing 1
MCMBP minichromosome maintenance complex binding protein
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL28 mitochondrial ribosomal protein L28
MRPL52 mitochondrial ribosomal protein L52
MTG1 mitochondrial ribosome-associated GTPase 1
MXD3 MAX dimerization protein 3
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NBEAL2 neurobeachin-like 2
NDE1 nudE neurodevelopment protein 1
NMB neuromedin B
NPIPB15 nuclear pore complex interacting protein family, member B15
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
PCYOX1 prenylcysteine oxidase 1
PELP1 proline, glutamate and leucine rich protein 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PMM2 phosphomannomutase 2
RAB33B RAB33B, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
REEP4 receptor accessory protein 4
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOBTB2 Rho-related BTB domain containing 2
RNF122 ring finger protein 122
RNF2 ring finger protein 2
RPAP2 RNA polymerase II associated protein 2
RPL23AP32 ribosomal protein L23a pseudogene 32
RPL23AP7 ribosomal protein L23a pseudogene 7
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RRP1 ribosomal RNA processing 1
SH3GL1 SH3-domain GRB2-like 1
SHARPIN SHANK-associated RH domain interactor
SHPK sedoheptulokinase
SIPA1 signal-induced proliferation-associated 1
SLC44A1 solute carrier family 44 (choline transporter), member 1
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
STK25 serine/threonine kinase 25
STX1A syntaxin 1A (brain)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAOK1 TAO kinase 1
TCTN2 tectonic family member 2
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM120B transmembrane protein 120B
TOLLIP toll interacting protein
TTPAL tocopherol (alpha) transfer protein-like
TUBB2A tubulin, beta 2A class IIa
UNC93B1 unc-93 homolog B1 (C. elegans)
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
ZNF250 zinc finger protein 250
ZNF32 zinc finger protein 32
ZNF350 zinc finger protein 350
ZNF701 zinc finger protein 701