fusidic acid-5353 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the fusidic acid-5353 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
APC adenomatous polyposis coli
APOC1 apolipoprotein C-I
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARID1A AT rich interactive domain 1A (SWI-like)
ARSB arylsulfatase B
ATG10 autophagy related 10
ATM ATM serine/threonine kinase
ATP11A ATPase, class VI, type 11A
ATP7B ATPase, Cu++ transporting, beta polypeptide
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
BHLHE40 basic helix-loop-helix family, member e40
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CASKIN2 CASK interacting protein 2
CCNO cyclin O
CD47 CD47 molecule
CDON cell adhesion associated, oncogene regulated
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CES2 carboxylesterase 2
CLCF1 cardiotrophin-like cytokine factor 1
CLMN calmin (calponin-like, transmembrane)
COL4A1 collagen, type IV, alpha 1
CRY2 cryptochrome circadian clock 2
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
EIF1 eukaryotic translation initiation factor 1
EMC1 ER membrane protein complex subunit 1
EML2 echinoderm microtubule associated protein like 2
ERN2 endoplasmic reticulum to nucleus signaling 2
F2R coagulation factor II (thrombin) receptor
FBXO9 F-box protein 9
FGD1 FYVE, RhoGEF and PH domain containing 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GATA2 GATA binding protein 2
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
HIST1H2AJ histone cluster 1, H2aj
HNMT histamine N-methyltransferase
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IKZF5 IKAROS family zinc finger 5 (Pegasus)
INSR insulin receptor
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGB5 integrin, beta 5
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
LBX1 ladybird homeobox 1
LMAN1 lectin, mannose-binding, 1
LMNA lamin A/C
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRRC20 leucine rich repeat containing 20
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LTBP4 latent transforming growth factor beta binding protein 4
MAPT microtubule-associated protein tau
MBTD1 mbt domain containing 1
MMP25 matrix metallopeptidase 25
MPPE1 metallophosphoesterase 1
MRPS12 mitochondrial ribosomal protein S12
MTRF1L mitochondrial translational release factor 1-like
NEK1 NIMA-related kinase 1
NOS1 nitric oxide synthase 1 (neuronal)
NR2F6 nuclear receptor subfamily 2, group F, member 6
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PACS1 phosphofurin acidic cluster sorting protein 1
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PCDH1 protocadherin 1
PCDHA6 protocadherin alpha 6
PDCD2 programmed cell death 2
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PFDN6 prefoldin subunit 6
PIBF1 progesterone immunomodulatory binding factor 1
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PPIA peptidylprolyl isomerase A (cyclophilin A)
RBM34 RNA binding motif protein 34
RGS10 regulator of G-protein signaling 10
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SIN3B SIN3 transcription regulator family member B
SIVA1 SIVA1, apoptosis-inducing factor
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SOGA1 suppressor of glucose, autophagy associated 1
SREBF2 sterol regulatory element binding transcription factor 2
STX1A syntaxin 1A (brain)
SUN2 Sad1 and UNC84 domain containing 2
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
TCP11L1 t-complex 11, testis-specific-like 1
TLDC1 TBC/LysM-associated domain containing 1
TRIM2 tripartite motif containing 2
TUBA3C tubulin, alpha 3c
TUSC2 tumor suppressor candidate 2
USB1 U6 snRNA biogenesis 1
VAC14 Vac14 homolog (S. cerevisiae)
VAV2 vav 2 guanine nucleotide exchange factor
ZER1 zyg-11 related, cell cycle regulator
ZNF34 zinc finger protein 34
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
AFF4 AF4/FMR2 family, member 4
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ANXA2P3 annexin A2 pseudogene 3
APOD apolipoprotein D
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
BAGE B melanoma antigen
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BBS7 Bardet-Biedl syndrome 7
BCL2L2 BCL2-like 2
C14ORF132 chromosome 14 open reading frame 132
C1ORF159 chromosome 1 open reading frame 159
CAMTA1 calmodulin binding transcription activator 1
CENPQ centromere protein Q
CHMP7 charged multivesicular body protein 7
CRELD1 cysteine-rich with EGF-like domains 1
CTSK cathepsin K
CUL9 cullin 9
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DAP death-associated protein
DCPS decapping enzyme, scavenger
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DET1 de-etiolated homolog 1 (Arabidopsis)
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
EFNA3 ephrin-A3
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EPHA2 EPH receptor A2
FAM118A family with sequence similarity 118, member A
FAM57A family with sequence similarity 57, member A
FGD6 FYVE, RhoGEF and PH domain containing 6
FSD1 fibronectin type III and SPRY domain containing 1
FYCO1 FYVE and coiled-coil domain containing 1
GBP2 guanylate binding protein 2, interferon-inducible
GCHFR GTP cyclohydrolase I feedback regulator
GLI3 GLI family zinc finger 3
GLS2 glutaminase 2 (liver, mitochondrial)
GPR19 G protein-coupled receptor 19
GPX2 glutathione peroxidase 2
HMBOX1 homeobox containing 1
HOXC10 homeobox C10
HSPA2 heat shock 70kDa protein 2
ICK intestinal cell (MAK-like) kinase
IFI6 interferon, alpha-inducible protein 6
IREB2 iron-responsive element binding protein 2
IRF6 interferon regulatory factor 6
ISG15 ISG15 ubiquitin-like modifier
KIF18A kinesin family member 18A
KIF20A kinesin family member 20A
KRBOX4 KRAB box domain containing 4
LMBR1L limb development membrane protein 1-like
LMNB1 lamin B1
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
MBIP MAP3K12 binding inhibitory protein 1
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MNS1 meiosis-specific nuclear structural 1
MXD3 MAX dimerization protein 3
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae)
OLFML3 olfactomedin-like 3
PCSK7 proprotein convertase subtilisin/kexin type 7
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PMP22 peripheral myelin protein 22
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
POU2F1 POU class 2 homeobox 1
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIBC2 RIB43A domain with coiled-coils 2
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RWDD2A RWD domain containing 2A
SETD1B SET domain containing 1B
SFT2D2 SFT2 domain containing 2
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC46A3 solute carrier family 46, member 3
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
STARD13 StAR-related lipid transfer (START) domain containing 13
SYCP2 synaptonemal complex protein 2
TCEAL1 transcription elongation factor A (SII)-like 1
TCTN1 tectonic family member 1
TDRD1 tudor domain containing 1
THOP1 thimet oligopeptidase 1
TMEM57 transmembrane protein 57
TMPRSS3 transmembrane protease, serine 3
TNRC6B trinucleotide repeat containing 6B
TP53BP1 tumor protein p53 binding protein 1
TXLNG taxilin gamma
USP18 ubiquitin specific peptidase 18
WDR19 WD repeat domain 19
ZC3H3 zinc finger CCCH-type containing 3
ZFP30 ZFP30 zinc finger protein
ZNF227 zinc finger protein 227
ZNF274 zinc finger protein 274
ZNF639 zinc finger protein 639
ZNF675 zinc finger protein 675