fusidic acid-6754 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the fusidic acid-6754 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
A4GALT alpha 1,4-galactosyltransferase
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADORA1 adenosine A1 receptor
ADPRH ADP-ribosylarginine hydrolase
AGXT alanine-glyoxylate aminotransferase
AHNAK AHNAK nucleoprotein
ALOXE3 arachidonate lipoxygenase 3
ANGPT4 angiopoietin 4
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ARTN artemin
ATP10B ATPase, class V, type 10B
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BTG2 BTG family, member 2
C1ORF54 chromosome 1 open reading frame 54
CACYBP calcyclin binding protein
CCDC40 coiled-coil domain containing 40
CCL5 chemokine (C-C motif) ligand 5
CD6 CD6 molecule
CD82 CD82 molecule
CD8B CD8b molecule
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLCA2 chloride channel accessory 2
CLCN7 chloride channel, voltage-sensitive 7
CLDN17 claudin 17
CNGB3 cyclic nucleotide gated channel beta 3
COL21A1 collagen, type XXI, alpha 1
COL9A3 collagen, type IX, alpha 3
CYBRD1 cytochrome b reductase 1
DCX doublecortin
EBF2 early B-cell factor 2
EDN1 endothelin 1
EGOT eosinophil granule ontogeny transcript (non-protein coding)
EML2 echinoderm microtubule associated protein like 2
ESRRB estrogen-related receptor beta
FGB fibrinogen beta chain
FGFR1 fibroblast growth factor receptor 1
FLOT1 flotillin 1
FMOD fibromodulin
FOXG1 forkhead box G1
GIMAP6 GTPase, IMAP family member 6
GLP1R glucagon-like peptide 1 receptor
GSN-AS1 GSN antisense RNA 1
HOXB2 homeobox B2
HOXD1 homeobox D1
HPCAL4 hippocalcin like 4
IAPP islet amyloid polypeptide
IGFBP1 insulin-like growth factor binding protein 1
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IRX4 iroquois homeobox 4
ITGB8 integrin, beta 8
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KLHL23 kelch-like family member 23
LAMA2 laminin, alpha 2
LTBP4 latent transforming growth factor beta binding protein 4
MAN1A2 mannosidase, alpha, class 1A, member 2
MAST3 microtubule associated serine/threonine kinase 3
MEP1B meprin A, beta
MMP9 matrix metallopeptidase 9
NEK1 NIMA-related kinase 1
NOL10 nucleolar protein 10
NOX1 NADPH oxidase 1
OMD osteomodulin
ONECUT2 one cut homeobox 2
OR1A2 olfactory receptor, family 1, subfamily A, member 2
PACRG PARK2 co-regulated
PALM paralemmin
PARVA parvin, alpha
PDCD6 programmed cell death 6
PDGFA platelet-derived growth factor alpha polypeptide
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA1A phospholipase A1 member A
PRB1 proline-rich protein BstNI subfamily 1
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBMS2 RNA binding motif, single stranded interacting protein 2
REEP1 receptor accessory protein 1
RGS10 regulator of G-protein signaling 10
RPS3A ribosomal protein S3A
S100A13 S100 calcium binding protein A13
SGSM3 small G protein signaling modulator 3
SHOX2 short stature homeobox 2
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12
SLCO1A2 solute carrier organic anion transporter family, member 1A2
TCEAL2 transcription elongation factor A (SII)-like 2
TMPRSS4 transmembrane protease, serine 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
UNC119 unc-119 homolog (C. elegans)
YIPF4 Yip1 domain family, member 4
ZNF3 zinc finger protein 3
ZNF37BP zinc finger protein 37B, pseudogene
ZNF500 zinc finger protein 500
ZNF506 zinc finger protein 506
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANXA2P1 annexin A2 pseudogene 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARMCX4 armadillo repeat containing, X-linked 4
AURKC aurora kinase C
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAK1 BCL2-antagonist/killer 1
BATF3 basic leucine zipper transcription factor, ATF-like 3
BEX4 brain expressed, X-linked 4
C1ORF159 chromosome 1 open reading frame 159
C1RL complement component 1, r subcomponent-like
C22ORF29 chromosome 22 open reading frame 29
CASS4 Cas scaffolding protein family member 4
CCNJL cyclin J-like
CHM choroideremia (Rab escort protein 1)
CLCN6 chloride channel, voltage-sensitive 6
CLIC3 chloride intracellular channel 3
CNN1 calponin 1, basic, smooth muscle
CNN2 calponin 2
CSF1R colony stimulating factor 1 receptor
CSRNP3 cysteine-serine-rich nuclear protein 3
DCSTAMP dendrocyte expressed seven transmembrane protein
DNAL4 dynein, axonemal, light chain 4
DTX2 deltex 2, E3 ubiquitin ligase
ERCC4 excision repair cross-complementation group 4
EYA3 EYA transcriptional coactivator and phosphatase 3
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FLT4 fms-related tyrosine kinase 4
FNTB farnesyltransferase, CAAX box, beta
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRS2 fibroblast growth factor receptor substrate 2
GDAP1 ganglioside induced differentiation associated protein 1
GJC1 gap junction protein, gamma 1, 45kDa
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GRB7 growth factor receptor-bound protein 7
GREB1L growth regulation by estrogen in breast cancer-like
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H2BO histone cluster 1, H2bo
HIST1H3C histone cluster 1, H3c
HOMER2 homer scaffolding protein 2
HP1BP3 heterochromatin protein 1, binding protein 3
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
ICOS inducible T-cell co-stimulator
IFI35 interferon-induced protein 35
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
INCENP inner centromere protein antigens 135/155kDa
IPO8 importin 8
IREB2 iron-responsive element binding protein 2
KLF13 Kruppel-like factor 13
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LINC00597 long intergenic non-protein coding RNA 597
LMO7 LIM domain 7
LPAR4 lysophosphatidic acid receptor 4
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MDM4 MDM4, p53 regulator
MN1 meningioma (disrupted in balanced translocation) 1
NEUROD1 neuronal differentiation 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPFFR1 neuropeptide FF receptor 1
NPIPB15 nuclear pore complex interacting protein family, member B15
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAQR6 progestin and adipoQ receptor family member VI
PDE8B phosphodiesterase 8B
PLD3 phospholipase D family, member 3
PLEKHO1 pleckstrin homology domain containing, family O member 1
POM121 POM121 transmembrane nucleoporin
POMT2 protein-O-mannosyltransferase 2
PRR4 proline rich 4 (lacrimal)
PTPRS protein tyrosine phosphatase, receptor type, S
PWAR5 Prader Willi/Angelman region RNA 5
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF126P1 ring finger protein 126 pseudogene 1
SCAMP5 secretory carrier membrane protein 5
SERGEF secretion regulating guanine nucleotide exchange factor
SLC16A6 solute carrier family 16, member 6
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC35F6 solute carrier family 35, member F6
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SNTG1 syntrophin, gamma 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCTN1 tectonic family member 1
THRAP3 thyroid hormone receptor associated protein 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TOM1 target of myb1 (chicken)
TWISTNB TWIST neighbor
UBQLN4 ubiquilin 4
VWA1 von Willebrand factor A domain containing 1
WDR4 WD repeat domain 4
WNT1 wingless-type MMTV integration site family, member 1
WNT7A wingless-type MMTV integration site family, member 7A
YEATS4 YEATS domain containing 4
ZFAND3 zinc finger, AN1-type domain 3
ZNF446 zinc finger protein 446
ZNF778 zinc finger protein 778
ZNHIT2 zinc finger, HIT-type containing 2
Funding