gabexate-4804 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the gabexate-4804 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADK adenosine kinase
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C6ORF62 chromosome 6 open reading frame 62
CA5B carbonic anhydrase VB, mitochondrial
CADM3 cell adhesion molecule 3
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CHKB choline kinase beta
CLDND1 claudin domain containing 1
CLIC2 chloride intracellular channel 2
CTBS chitobiase, di-N-acetyl-
DBT dihydrolipoamide branched chain transacylase E2
DCAF13 DDB1 and CUL4 associated factor 13
EAF2 ELL associated factor 2
EPOR erythropoietin receptor
EWSR1 EWS RNA-binding protein 1
EXOC5 exocyst complex component 5
FAAH fatty acid amide hydrolase
FAS Fas cell surface death receptor
FGF13 fibroblast growth factor 13
FH fumarate hydratase
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GRIK5 glutamate receptor, ionotropic, kainate 5
GULP1 GULP, engulfment adaptor PTB domain containing 1
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HOXA4 homeobox A4
HSPA13 heat shock protein 70kDa family, member 13
IFI6 interferon, alpha-inducible protein 6
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KLHL22 kelch-like family member 22
KRIT1 KRIT1, ankyrin repeat containing
KRT20 keratin 20, type I
LAT2 linker for activation of T cells family, member 2
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LRP12 low density lipoprotein receptor-related protein 12
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTN1 listerin E3 ubiquitin protein ligase 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK14 mitogen-activated protein kinase 14
MBNL1 muscleblind-like splicing regulator 1
MCTP1 multiple C2 domains, transmembrane 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED20 mediator complex subunit 20
MIER2 mesoderm induction early response 1, family member 2
MTM1 myotubularin 1
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NFX1 nuclear transcription factor, X-box binding 1
NOTCH2 notch 2
NPY1R neuropeptide Y receptor Y1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PEX3 peroxisomal biogenesis factor 3
PICALM phosphatidylinositol binding clathrin assembly protein
PLAGL1 pleiomorphic adenoma gene-like 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RAB27A RAB27A, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RALB v-ral simian leukemia viral oncogene homolog B
RBM26 RNA binding motif protein 26
REM1 RAS (RAD and GEM)-like GTP-binding 1
REPS1 RALBP1 associated Eps domain containing 1
RHOQ ras homolog family member Q
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RRBP1 ribosome binding protein 1
RWDD3 RWD domain containing 3
RYK receptor-like tyrosine kinase
SCARB1 scavenger receptor class B, member 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SH3BP2 SH3-domain binding protein 2
SLC17A2 solute carrier family 17, member 2
SLC35F5 solute carrier family 35, member F5
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMAD5 SMAD family member 5
SOAT1 sterol O-acyltransferase 1
SOS2 son of sevenless homolog 2 (Drosophila)
STK24 serine/threonine kinase 24
STRN3 striatin, calmodulin binding protein 3
SYCE1L synaptonemal complex central element protein 1-like
TANK TRAF family member-associated NFKB activator
TCEAL1 transcription elongation factor A (SII)-like 1
TCF12 transcription factor 12
THBD thrombomodulin
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPD52 tumor protein D52
TRIM2 tripartite motif containing 2
TRIM36 tripartite motif containing 36
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TSC22D3 TSC22 domain family, member 3
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YIPF4 Yip1 domain family, member 4
ZNF639 zinc finger protein 639
ZNF675 zinc finger protein 675
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ADTRP androgen-dependent TFPI-regulating protein
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ALPK1 alpha-kinase 1
APOC4 apolipoprotein C-IV
ARMCX4 armadillo repeat containing, X-linked 4
ARRB2 arrestin, beta 2
ASPHD1 aspartate beta-hydroxylase domain containing 1
BBC3 BCL2 binding component 3
BRPF1 bromodomain and PHD finger containing, 1
CCDC85C coiled-coil domain containing 85C
CCNJ cyclin J
CD79B CD79b molecule, immunoglobulin-associated beta
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CES3 carboxylesterase 3
CHPF chondroitin polymerizing factor
CHRM3 cholinergic receptor, muscarinic 3
CPED1 cadherin-like and PC-esterase domain containing 1
CPTP ceramide-1-phosphate transfer protein
CRIP1 cysteine-rich protein 1 (intestinal)
DGKD diacylglycerol kinase, delta 130kDa
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNAL4 dynein, axonemal, light chain 4
DTX2 deltex 2, E3 ubiquitin ligase
ENO2 enolase 2 (gamma, neuronal)
EVPL envoplakin
FAM46C family with sequence similarity 46, member C
FBXO2 F-box protein 2
FILIP1L filamin A interacting protein 1-like
FRMD4A FERM domain containing 4A
FUZ fuzzy planar cell polarity protein
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPC3 glypican 3
GRB7 growth factor receptor-bound protein 7
GRTP1 growth hormone regulated TBC protein 1
GTF2I general transcription factor IIi
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HHAT hedgehog acyltransferase
HIST1H2BJ histone cluster 1, H2bj
HOXC11 homeobox C11
HP1BP3 heterochromatin protein 1, binding protein 3
IFT140 intraflagellar transport 140
IL15RA interleukin 15 receptor, alpha
IL4R interleukin 4 receptor
IQCC IQ motif containing C
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KCTD17 potassium channel tetramerization domain containing 17
KIF13A kinesin family member 13A
KLF2 Kruppel-like factor 2
KLHL25 kelch-like family member 25
LAMB3 laminin, beta 3
LARP6 La ribonucleoprotein domain family, member 6
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LHX6 LIM homeobox 6
LIME1 Lck interacting transmembrane adaptor 1
MRPS18C mitochondrial ribosomal protein S18C
MUC3B mucin 3B, cell surface associated
NBEAL2 neurobeachin-like 2
NDRG4 NDRG family member 4
NEUROD4 neuronal differentiation 4
NRGN neurogranin (protein kinase C substrate, RC3)
NTHL1 nth endonuclease III-like 1 (E. coli)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PDE8B phosphodiesterase 8B
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PRF1 perforin 1 (pore forming protein)
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PTPRU protein tyrosine phosphatase, receptor type, U
PYCRL pyrroline-5-carboxylate reductase-like
QSER1 glutamine and serine rich 1
RAB36 RAB36, member RAS oncogene family
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF39 ring finger protein 39
SAMD9 sterile alpha motif domain containing 9
SDC3 syndecan 3
SECTM1 secreted and transmembrane 1
SETD8 SET domain containing (lysine methyltransferase) 8
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SND1-IT1 SND1 intronic transcript 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STX5 syntaxin 5
SYMPK symplekin
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM134 transmembrane protein 134
TMEM45A transmembrane protein 45A
TPCN1 two pore segment channel 1
TPRA1 transmembrane protein, adipocyte asscociated 1
TSGA10 testis specific, 10
UBQLN4 ubiquilin 4
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF324 zinc finger protein 324
ZNF34 zinc finger protein 34
ZNF394 zinc finger protein 394
ZNF446 zinc finger protein 446
ZNF747 zinc finger protein 747
ZNF804A zinc finger protein 804A