gain Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Similar Terms
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Genes

366 genes co-occuring with the biological term gain in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACP1 acid phosphatase 1, soluble
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADRA1A adrenoceptor alpha 1A
ADRA2A adrenoceptor alpha 2A
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AGRP agouti related neuropeptide
AHSG alpha-2-HS-glycoprotein
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALB albumin
ALK anaplastic lymphoma receptor tyrosine kinase
ANKK1 ankyrin repeat and kinase domain containing 1
ANXA1 annexin A1
ANXA2 annexin A2
ANXA2R annexin A2 receptor
APC adenomatous polyposis coli
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AR androgen receptor
ASCL2 achaete-scute family bHLH transcription factor 2
B2M beta-2-microglobulin
BAG1 BCL2-associated athanogene
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL6 B-cell CLL/lymphoma 6
BDNF brain-derived neurotrophic factor
BMP2 bone morphogenetic protein 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BST2 bone marrow stromal cell antigen 2
C11ORF72 chromosome 11 open reading frame 72
C3 complement component 3
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit
CAMP cathelicidin antimicrobial peptide
CARTPT CART prepropeptide
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CCK cholecystokinin
CCKAR cholecystokinin A receptor
CCKBR cholecystokinin B receptor
CCND1 cyclin D1
CCNE1 cyclin E1
CD1D CD1d molecule
CD4 CD4 molecule
CD44 CD44 molecule (Indian blood group)
CD46 CD46 molecule, complement regulatory protein
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD59 CD59 molecule, complement regulatory protein
CD9 CD9 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CELF2 CUGBP, Elav-like family member 2
CFB complement factor B
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CGB5 chorionic gonadotropin, beta polypeptide 5
CKS1B CDC28 protein kinase regulatory subunit 1B
CLU clusterin
CNGA3 cyclic nucleotide gated channel alpha 3
CNGB3 cyclic nucleotide gated channel beta 3
CNR1 cannabinoid receptor 1 (brain)
CNTF ciliary neurotrophic factor
COG8 component of oligomeric golgi complex 8
COL6A3 collagen, type VI, alpha 3
COMT catechol-O-methyltransferase
CP ceruloplasmin (ferroxidase)
CRP C-reactive protein, pentraxin-related
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CST3 cystatin C
CTBP2 C-terminal binding protein 2
CTCF CCCTC-binding factor (zinc finger protein)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CXADR coxsackie virus and adenovirus receptor
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCR4 chemokine (C-X-C motif) receptor 4
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DAD1P1 defender against cell death 1 pseudogene 1
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1
DEK DEK proto-oncogene
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DKC1 dyskeratosis congenita 1, dyskerin
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLD dihydrolipoamide dehydrogenase
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DRD5 dopamine receptor D5
DROSHA drosha, ribonuclease type III
DUT deoxyuridine triphosphatase
DUX4L1 double homeobox 4 like 1
E2F3 E2F transcription factor 3
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EIF3H eukaryotic translation initiation factor 3, subunit H
EN2 engrailed homeobox 2
EPHA2 EPH receptor A2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FABP4 fatty acid binding protein 4, adipocyte
FAM111A family with sequence similarity 111, member A
FANCL Fanconi anemia, complementation group L
FGF21 fibroblast growth factor 21
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FHL1 four and a half LIM domains 1
FKBP1A FK506 binding protein 1A, 12kDa
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLT3 fms-related tyrosine kinase 3
FMR1 fragile X mental retardation 1
FN1 fibronectin 1
FOXC1 forkhead box C1
FOXG1 forkhead box G1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FRZB frizzled-related protein
FTO fat mass and obesity associated
FUS FUS RNA binding protein
GAB1 GRB2-associated binding protein 1
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GARS glycyl-tRNA synthetase
GATA6 GATA binding protein 6
GBA glucosidase, beta, acid
GCK glucokinase (hexokinase 4)
GH1 growth hormone 1
GHR growth hormone receptor
GHRL ghrelin/obestatin prepropeptide
GJB1 gap junction protein, beta 1, 32kDa
GJB2 gap junction protein, beta 2, 26kDa
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNAS GNAS complex locus
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GRHL2 grainyhead-like 2 (Drosophila)
GSTT1 glutathione S-transferase theta 1
H19 H19, imprinted maternally expressed transcript (non-protein coding)
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HMGA2 high mobility group AT-hook 2
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HOXA13 homeobox A13
HRH1 histamine receptor H1
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTT huntingtin
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IDI1 isopentenyl-diphosphate delta isomerase 1
IDI2 isopentenyl-diphosphate delta isomerase 2
IFNA1 interferon, alpha 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2 insulin-like growth factor 2
IGFBP3 insulin-like growth factor binding protein 3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL1B interleukin 1, beta
IL2 interleukin 2
IL6 interleukin 6
INHBB inhibin, beta B
INO80 INO80 complex subunit
IQGAP1 IQ motif containing GTPase activating protein 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK3 Janus kinase 3
JOSD1 Josephin domain containing 1
JPH2 junctophilin 2
JPH3 junctophilin 3
KAT6A K(lysine) acetyltransferase 6A
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KDM4A lysine (K)-specific demethylase 4A
KDR kinase insert domain receptor
KIAA1257 KIAA1257
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KMT2A lysine (K)-specific methyltransferase 2A
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRAS Kirsten rat sarcoma viral oncogene homolog
LEF1 lymphoid enhancer-binding factor 1
LEP leptin
LEPR leptin receptor
LHCGR luteinizing hormone/choriogonadotropin receptor
LPL lipoprotein lipase
LRRK2 leucine-rich repeat kinase 2
MAGEA11 melanoma antigen family A11
MALT1 MALT1 paracaspase
MAPK14 mitogen-activated protein kinase 14
MBD1 methyl-CpG binding domain protein 1
MBNL1 muscleblind-like splicing regulator 1
MC4R melanocortin 4 receptor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MET MET proto-oncogene, receptor tyrosine kinase
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MIR142 microRNA 142
MIR151A microRNA 151a
MIR17 microRNA 17
MMP9 matrix metallopeptidase 9
MPZ myelin protein zero
MT-ATP6 ATP synthase F0 subunit 6
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC2 mucin 2, oligomeric mucus/gel-forming
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NFE2L2 nuclear factor, erythroid 2-like 2
NKX2-1 NK2 homeobox 1
NKX3-1 NK3 homeobox 1
NOD2 nucleotide-binding oligomerization domain containing 2
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPY neuropeptide Y
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C1P1 nuclear receptor subfamily 3, group C, member 1 pseudogene 1
NSUN2 NOP2/Sun RNA methyltransferase family, member 2
NUCB2 nucleobindin 2
NUPR1 nuclear protein, transcriptional regulator, 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OPRM1 opioid receptor, mu 1
OVGP1 oviductal glycoprotein 1, 120kDa
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
PBX1 pre-B-cell leukemia homeobox 1
PCNA proliferating cell nuclear antigen
PCSK9 proprotein convertase subtilisin/kexin type 9
PDF peptide deformylase (mitochondrial)
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PECAM1 platelet/endothelial cell adhesion molecule 1
PGD phosphogluconate dehydrogenase
PGR progesterone receptor
PHOX2B paired-like homeobox 2b
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLIN1 perilipin 1
POLH polymerase (DNA directed), eta
POMC proopiomelanocortin
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCB protein kinase C, beta
PROM1 prominin 1
PRPF31 pre-mRNA processing factor 31
PRSS1 protease, serine, 1 (trypsin 1)
PSEN1 presenilin 1
PTEN phosphatase and tensin homolog
PTGES prostaglandin E synthase
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PVT1 Pvt1 oncogene (non-protein coding)
PYY peptide YY
RAB7A RAB7A, member RAS oncogene family
RARG retinoic acid receptor, gamma
RB1 retinoblastoma 1
REN renin
RET ret proto-oncogene
RHO rhodopsin
RNASE8 ribonuclease, RNase A family, 8
RORA RAR-related orphan receptor A
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPL30 ribosomal protein L30
RPL8 ribosomal protein L8
RPS20 ribosomal protein S20
RYR1 ryanodine receptor 1 (skeletal)
RYR2 ryanodine receptor 2 (cardiac)
S100B S100 calcium binding protein B
S1PR1 sphingosine-1-phosphate receptor 1
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN4A sodium channel, voltage gated, type IV alpha subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SDC4 syndecan 4
SEC62 SEC62 homolog (S. cerevisiae)
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SETBP1 SET binding protein 1
SFRP1 secreted frizzled-related protein 1
SH3BP2 SH3-domain binding protein 2
SHANK3 SH3 and multiple ankyrin repeat domains 3
SIRT1 sirtuin 1
SKIL SKI-like proto-oncogene
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC16A4 solute carrier family 16, member 4
SLC22A18 solute carrier family 22, member 18
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SMAD5 SMAD family member 5
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SOX15 SRY (sex determining region Y)-box 15
SOX2 SRY (sex determining region Y)-box 2
SOX9 SRY (sex determining region Y)-box 9
SPP1 secreted phosphoprotein 1
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SRF serum response factor (c-fos serum response element-binding transcription factor)
SSTR2 somatostatin receptor 2
STIM1 stromal interaction molecule 1
T T, brachyury homolog (mouse)
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TARDBP TAR DNA binding protein
TASP1 taspase, threonine aspartase, 1
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBX1 T-box 1
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TDP1 tyrosyl-DNA phosphodiesterase 1
TEAD4 TEA domain family member 4
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TF transferrin
TLR2 toll-like receptor 2
TMPRSS2 transmembrane protease, serine 2
TNF tumor necrosis factor
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TOP2A topoisomerase (DNA) II alpha 170kDa
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
TP73 tumor protein p73
TPH1 tryptophan hydroxylase 1
TPPP tubulin polymerization promoting protein
TRIB3 tribbles pseudokinase 3
TRIM33 tripartite motif containing 33
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TWIST1 twist family bHLH transcription factor 1
UBE2I ubiquitin-conjugating enzyme E2I
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1
UBIAD1 UbiA prenyltransferase domain containing 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VIM vimentin
WISP2 WNT1 inducible signaling pathway protein 2
WWOX WW domain containing oxidoreductase
YAP1 Yes-associated protein 1
YY1 YY1 transcription factor
ZDHHC11 zinc finger, DHHC-type containing 11
ZFP36 ZFP36 ring finger protein