| Dataset | GO Cellular Component Annotations 2015 |
| Category | structural or functional annotations |
| Type | cellular component |
| Description | A protein complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. The complex binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs and suppresses their translation by blocking the recruitment of the 43S ribosomal complex to m7G cap-bound eIF4G. In humans it includes RPL13A, EPRS, SYNCRIP and GAPDH; mouse complexes lack SYNCRIP. (Gene Ontology, GO_0097452) |
| External Link | http://amigo.geneontology.org/amigo/term/GO:0097452 |
| Similar Terms | |
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4 proteins localized to the gait complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.
