galantamine-2787 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the galantamine-2787 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX2 acyl-CoA oxidase 2, branched chain
ALCAM activated leukocyte cell adhesion molecule
ANKRD12 ankyrin repeat domain 12
ARC activity-regulated cytoskeleton-associated protein
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL4C ADP-ribosylation factor-like 4C
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAIAP3 BAI1-associated protein 3
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BTN2A2 butyrophilin, subfamily 2, member A2
C22ORF46 chromosome 22 open reading frame 46
C9ORF156 chromosome 9 open reading frame 156
CABIN1 calcineurin binding protein 1
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC28B coiled-coil domain containing 28B
CD3D CD3d molecule, delta (CD3-TCR complex)
CDK13 cyclin-dependent kinase 13
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CEP164 centrosomal protein 164kDa
CERS4 ceramide synthase 4
CGA glycoprotein hormones, alpha polypeptide
CLTA clathrin, light chain A
COL17A1 collagen, type XVII, alpha 1
COL19A1 collagen, type XIX, alpha 1
COL1A1 collagen, type I, alpha 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DHRS12 dehydrogenase/reductase (SDR family) member 12
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DMTN dematin actin binding protein
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DSPP dentin sialophosphoprotein
DYM dymeclin
DZIP1 DAZ interacting zinc finger protein 1
EMC1 ER membrane protein complex subunit 1
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
FAM46C family with sequence similarity 46, member C
FBXL8 F-box and leucine-rich repeat protein 8
FBXO9 F-box protein 9
FGF6 fibroblast growth factor 6
FGL1 fibrinogen-like 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GMPR guanosine monophosphate reductase
GPR143 G protein-coupled receptor 143
GPR21 G protein-coupled receptor 21
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HPX hemopexin
IL36G interleukin 36, gamma
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KIAA0319L KIAA0319-like
LEFTY1 left-right determination factor 1
MAP2K5 mitogen-activated protein kinase kinase 5
MAP2K7 mitogen-activated protein kinase kinase 7
MTL5 metallothionein-like 5, testis-specific (tesmin)
MYO1B myosin IB
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
NEB nebulin
NRG2 neuregulin 2
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
OLFML2A olfactomedin-like 2A
PACS1 phosphofurin acidic cluster sorting protein 1
PDGFA platelet-derived growth factor alpha polypeptide
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POFUT1 protein O-fucosyltransferase 1
PON3 paraoxonase 3
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PTCRA pre T-cell antigen receptor alpha
RAB6B RAB6B, member RAS oncogene family
RBM3 RNA binding motif (RNP1, RRM) protein 3
RFPL3 ret finger protein-like 3
RND1 Rho family GTPase 1
RNLS renalase, FAD-dependent amine oxidase
SAFB scaffold attachment factor B
SIRT3 sirtuin 3
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMR3A submaxillary gland androgen regulated protein 3A
SPDEF SAM pointed domain containing ETS transcription factor
SRSF5 serine/arginine-rich splicing factor 5
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TCF3 transcription factor 3
TTC9 tetratricopeptide repeat domain 9
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBA6 ubiquitin-like modifier activating enzyme 6
UBXN6 UBX domain protein 6
UROD uroporphyrinogen decarboxylase
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIM vimentin
VNN2 vanin 2
WDR62 WD repeat domain 62
ZER1 zyg-11 related, cell cycle regulator
ZFPL1 zinc finger protein-like 1
ZMAT4 zinc finger, matrin-type 4

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
AEN apoptosis enhancing nuclease
AHDC1 AT hook, DNA binding motif, containing 1
APOLD1 apolipoprotein L domain containing 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATG2A autophagy related 2A
AUP1 ancient ubiquitous protein 1
C11ORF30 chromosome 11 open reading frame 30
C7ORF43 chromosome 7 open reading frame 43
CBX8 chromobox homolog 8
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC132 coiled-coil domain containing 132
CCDC85C coiled-coil domain containing 85C
CCDC92 coiled-coil domain containing 92
CCNT1 cyclin T1
CORO2A coronin, actin binding protein, 2A
CORT cortistatin
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DVL1 dishevelled segment polarity protein 1
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EFNA3 ephrin-A3
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPHA2 EPH receptor A2
ETAA1 Ewing tumor-associated antigen 1
FAN1 FANCD2/FANCI-associated nuclease 1
FBXL6 F-box and leucine-rich repeat protein 6
FMO4 flavin containing monooxygenase 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GAMT guanidinoacetate N-methyltransferase
GK3P glycerol kinase 3 pseudogene
GOLGA8B golgin A8 family, member B
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H3E histone cluster 1, H3e
HIST1H4D histone cluster 1, H4d
HRAS Harvey rat sarcoma viral oncogene homolog
IFT22 intraflagellar transport 22
IGFBP6 insulin-like growth factor binding protein 6
INPP5J inositol polyphosphate-5-phosphatase J
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KLF3 Kruppel-like factor 3 (basic)
KPTN kaptin (actin binding protein)
LOC730101 uncharacterized LOC730101
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LY6D lymphocyte antigen 6 complex, locus D
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MBTD1 mbt domain containing 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCOLN1 mucolipin 1
METTL16 methyltransferase like 16
MOSPD3 motile sperm domain containing 3
MTERF4 mitochondrial transcription termination factor 4
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NCALD neurocalcin delta
NDE1 nudE neurodevelopment protein 1
NIPAL2 NIPA-like domain containing 2
NOL10 nucleolar protein 10
NPFFR1 neuropeptide FF receptor 1
PARD6B par-6 family cell polarity regulator beta
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHB3 protocadherin beta 3
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G10 phospholipase A2, group X
PLA2G3 phospholipase A2, group III
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PPT2 palmitoyl-protein thioesterase 2
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PSKH1 protein serine kinase H1
PTPRE protein tyrosine phosphatase, receptor type, E
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
REEP1 receptor accessory protein 1
SAYSD1 SAYSVFN motif domain containing 1
SCRN3 secernin 3
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SNAI2 snail family zinc finger 2
SOX12 SRY (sex determining region Y)-box 12
SPIDR scaffolding protein involved in DNA repair
SRPX sushi-repeat containing protein, X-linked
STON1 stonin 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TARP TCR gamma alternate reading frame protein
TCTN1 tectonic family member 1
TDRD1 tudor domain containing 1
TEP1 telomerase-associated protein 1
TPST2 tyrosylprotein sulfotransferase 2
TRAIP TRAF interacting protein
UBXN8 UBX domain protein 8
VWA1 von Willebrand factor A domain containing 1
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZMAT5 zinc finger, matrin-type 5
ZNF428 zinc finger protein 428
ZNF701 zinc finger protein 701