galantamine-4772 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the galantamine-4772 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
AASS aminoadipate-semialdehyde synthase
ACRV1 acrosomal vesicle protein 1
ACTG2 actin, gamma 2, smooth muscle, enteric
ARR3 arrestin 3, retinal (X-arrestin)
C19ORF66 chromosome 19 open reading frame 66
C21ORF2 chromosome 21 open reading frame 2
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CCDC85B coiled-coil domain containing 85B
CCNT2 cyclin T2
CD101 CD101 molecule
CD8B CD8b molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CLCA2 chloride channel accessory 2
CLDN11 claudin 11
CLEC2B C-type lectin domain family 2, member B
CNTD2 cyclin N-terminal domain containing 2
CPN2 carboxypeptidase N, polypeptide 2
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
CXCR4 chemokine (C-X-C motif) receptor 4
DIEXF digestive organ expansion factor homolog (zebrafish)
DMPK dystrophia myotonica-protein kinase
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNASE1L3 deoxyribonuclease I-like 3
DRD2 dopamine receptor D2
DUSP10 dual specificity phosphatase 10
F5 coagulation factor V (proaccelerin, labile factor)
FBXL7 F-box and leucine-rich repeat protein 7
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FGL1 fibrinogen-like 1
FNTB farnesyltransferase, CAAX box, beta
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB1 GRB2-associated binding protein 1
GAP43 growth associated protein 43
GGT1 gamma-glutamyltransferase 1
GLIPR1 GLI pathogenesis-related 1
GLP1R glucagon-like peptide 1 receptor
GLRB glycine receptor, beta
GPSM3 G-protein signaling modulator 3
GRB10 growth factor receptor-bound protein 10
GREB1L growth regulation by estrogen in breast cancer-like
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H2BM histone cluster 1, H2bm
HLF hepatic leukemia factor
HNF4A hepatocyte nuclear factor 4, alpha
HP haptoglobin
ICOSLG inducible T-cell co-stimulator ligand
IGLJ3 immunoglobulin lambda joining 3
IL11 interleukin 11
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INA internexin neuronal intermediate filament protein, alpha
INHBC inhibin, beta C
INHBE inhibin, beta E
IRF8 interferon regulatory factor 8
JPH3 junctophilin 3
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLF12 Kruppel-like factor 12
LEF1 lymphoid enhancer-binding factor 1
LINC00312 long intergenic non-protein coding RNA 312
NOL12 nucleolar protein 12
NPAS2 neuronal PAS domain protein 2
NSUN6 NOP2/Sun domain family, member 6
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR1F2P olfactory receptor, family 1, subfamily F, member 2, pseudogene
OR2S2 olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene)
OSBPL3 oxysterol binding protein-like 3
OVGP1 oviductal glycoprotein 1, 120kDa
PCDH11Y protocadherin 11 Y-linked
PLAC4 placenta-specific 4
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLLP plasmolipin
POU4F1 POU class 4 homeobox 1
RIF1 replication timing regulatory factor 1
RPS14 ribosomal protein S14
SCARF1 scavenger receptor class F, member 1
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SPINK1 serine peptidase inhibitor, Kazal type 1
STK11 serine/threonine kinase 11
SUGP1 SURP and G patch domain containing 1
TAT tyrosine aminotransferase
TCP11L1 t-complex 11, testis-specific-like 1
TGM2 transglutaminase 2
TSC22D4 TSC22 domain family, member 4
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
UPK3B uroplakin 3B
VCAN versican
ZFHX2 zinc finger homeobox 2
ZNF287 zinc finger protein 287
ZNF419 zinc finger protein 419
ZNF589 zinc finger protein 589
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ACVR1 activin A receptor, type I
ADGRA3 adhesion G protein-coupled receptor A3
AUH AU RNA binding protein/enoyl-CoA hydratase
BBS10 Bardet-Biedl syndrome 10
BCL2L2 BCL2-like 2
BCL9 B-cell CLL/lymphoma 9
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BRIX1 BRX1, biogenesis of ribosomes
C1ORF109 chromosome 1 open reading frame 109
CARS2 cysteinyl-tRNA synthetase 2, mitochondrial (putative)
CBX4 chromobox homolog 4
CCNL2 cyclin L2
CDKN2AIP CDKN2A interacting protein
CEP72 centrosomal protein 72kDa
CEP97 centrosomal protein 97kDa
CHUK conserved helix-loop-helix ubiquitous kinase
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DSN1 DSN1, MIS12 kinetochore complex component
EPHA2 EPH receptor A2
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXO3 F-box protein 3
FKBP10 FK506 binding protein 10, 65 kDa
FPGT fucose-1-phosphate guanylyltransferase
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GINS4 GINS complex subunit 4 (Sld5 homolog)
GPALPP1 GPALPP motifs containing 1
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HAUS6 HAUS augmin-like complex, subunit 6
HCFC2 host cell factor C2
HEATR3 HEAT repeat containing 3
IFT81 intraflagellar transport 81
JUNB jun B proto-oncogene
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCTD5 potassium channel tetramerization domain containing 5
KIAA1551 KIAA1551
LACTB2 lactamase, beta 2
LINC00115 long intergenic non-protein coding RNA 115
LMNB1 lamin B1
LYRM2 LYR motif containing 2
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP1S microtubule-associated protein 1S
MEIS1 Meis homeobox 1
MEIS2 Meis homeobox 2
MFSD11 major facilitator superfamily domain containing 11
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NMU neuromedin U
NR1H2 nuclear receptor subfamily 1, group H, member 2
NUBPL nucleotide binding protein-like
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OGFRL1 opioid growth factor receptor-like 1
OXR1 oxidation resistance 1
PACS1 phosphofurin acidic cluster sorting protein 1
PARPBP PARP1 binding protein
PC pyruvate carboxylase
PELI1 pellino E3 ubiquitin protein ligase 1
PLD3 phospholipase D family, member 3
RARS arginyl-tRNA synthetase
RFWD3 ring finger and WD repeat domain 3
RFX7 regulatory factor X, 7
RIN2 Ras and Rab interactor 2
SAYSD1 SAYSVFN motif domain containing 1
SCML1 sex comb on midleg-like 1 (Drosophila)
SGMS1 sphingomyelin synthase 1
SHCBP1 SHC SH2-domain binding protein 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SNX16 sorting nexin 16
STBD1 starch binding domain 1
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TCTN1 tectonic family member 1
THAP7 THAP domain containing 7
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM184C transmembrane protein 184C
TMEM2 transmembrane protein 2
TMEM62 transmembrane protein 62
TMOD3 tropomodulin 3 (ubiquitous)
TRAPPC11 trafficking protein particle complex 11
TRIM5 tripartite motif containing 5
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
USP16 ubiquitin specific peptidase 16
USP27X ubiquitin specific peptidase 27, X-linked
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
XPC xeroderma pigmentosum, complementation group C
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF195 zinc finger protein 195
ZNF217 zinc finger protein 217
ZNF271P zinc finger protein 271, pseudogene
ZNF430 zinc finger protein 430
ZNF446 zinc finger protein 446
ZNF586 zinc finger protein 586
ZNF623 zinc finger protein 623
ZNF652 zinc finger protein 652
ZNF665 zinc finger protein 665
ZNF721 zinc finger protein 721