gallbladder carcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A gallbladder cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. (Human Disease Ontology, DOID_4948)
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Genes

194 genes co-occuring with the disease gallbladder carcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ZNF135 zinc finger protein 135 1.45572
TP53 tumor protein p53 1.38341
LAPTM4B lysosomal protein transmembrane 4 beta 1.32367
PDPN podoplanin 1.31319
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.20656
KRAS Kirsten rat sarcoma viral oncogene homolog 1.2018
HRAS Harvey rat sarcoma viral oncogene homolog 1.1841
PCNA proliferating cell nuclear antigen 1.01849
MUC2 mucin 2, oligomeric mucus/gel-forming 0.986428
MUC1 mucin 1, cell surface associated 0.976744
NMT1 N-myristoyltransferase 1 0.964148
NEK7 NIMA-related kinase 7 0.945354
TMEM11 transmembrane protein 11 0.934556
BTC betacellulin 0.927519
MUC4 mucin 4, cell surface associated 0.890488
GBAS glioblastoma amplified sequence 0.887208
S100A9 S100 calcium binding protein A9 0.811001
CDKN2A cyclin-dependent kinase inhibitor 2A 0.807718
C19ORF48 chromosome 19 open reading frame 48 0.776159
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.746391
CLEC3A C-type lectin domain family 3, member A 0.737865
CLEC2B C-type lectin domain family 2, member B 0.732596
EBAG9 estrogen receptor binding site associated, antigen, 9 0.71925
PDIA2 protein disulfide isomerase family A, member 2 0.714811
KRT7 keratin 7, type II 0.71078
AFP alpha-fetoprotein 0.709572
CLEC10A C-type lectin domain family 10, member A 0.707559
INF2 inverted formin, FH2 and WH2 domain containing 0.701124
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.694702
ERBB2 erb-b2 receptor tyrosine kinase 2 0.685091
CHD5 chromodomain helicase DNA binding protein 5 0.66596
MTDH metadherin 0.661197
EPHA7 EPH receptor A7 0.637102
FHIT fragile histidine triad 0.6214
NEK8 NIMA-related kinase 8 0.615921
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.611229
WDR1 WD repeat domain 1 0.606152
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.587054
FCGBP Fc fragment of IgG binding protein 0.586276
MLH1 mutL homolog 1 0.58005
CD82 CD82 molecule 0.567997
CHGA chromogranin A 0.551298
MUC6 mucin 6, oligomeric mucus/gel-forming 0.531928
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.531154
PCBP1 poly(rC) binding protein 1 0.526904
EGFR epidermal growth factor receptor 0.51188
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 0.511112
FBXO8 F-box protein 8 0.508808
KRT20 keratin 20, type I 0.505739
CCND1 cyclin D1 0.498849
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.49274
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.484744
ANXA5 annexin A5 0.479807
CD44 CD44 molecule (Indian blood group) 0.467684
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 0.463905
BAX BCL2-associated X protein 0.455601
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.440162
FGFBP1 fibroblast growth factor binding protein 1 0.436026
GDI2 GDP dissociation inhibitor 2 0.430768
ALPPL2 alkaline phosphatase, placental-like 2 0.42364
ALPP alkaline phosphatase, placental 0.423265
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.423265
ALPL alkaline phosphatase, liver/bone/kidney 0.42289
ERP29 endoplasmic reticulum protein 29 0.421765
PSCA prostate stem cell antigen 0.415773
MSI1 musashi RNA-binding protein 1 0.413527
REG4 regenerating islet-derived family, member 4 0.412031
CKS2 CDC28 protein kinase regulatory subunit 2 0.400453
FOXM1 forkhead box M1 0.397471
PEBP1 phosphatidylethanolamine binding protein 1 0.395235
PLAGL2 pleiomorphic adenoma gene-like 2 0.394863
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.381481
MMP2 matrix metallopeptidase 2 0.378514
APP amyloid beta (A4) precursor protein 0.373698
ASMT acetylserotonin O-methyltransferase 0.357446
WISP2 WNT1 inducible signaling pathway protein 2 0.355972
GIPC1 GIPC PDZ domain containing family, member 1 0.351923
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.346777
ELAVL1 ELAV like RNA binding protein 1 0.345675
SST somatostatin 0.342739
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.340906
CD24 CD24 molecule 0.340906
MKI67 marker of proliferation Ki-67 0.340173
ADGRE5 adhesion G protein-coupled receptor E5 0.339073
TIMP2 TIMP metallopeptidase inhibitor 2 0.33066
VEGFC vascular endothelial growth factor C 0.328834
TIMP3 TIMP metallopeptidase inhibitor 3 0.32774
TSC1 tuberous sclerosis 1 0.325916
CDX2 caudal type homeobox 2 0.321181
DDX53 DEAD (Asp-Glu-Ala-Asp) box polypeptide 53 0.319363
CLIC1 chloride intracellular channel 1 0.317182
ENO2 enolase 2 (gamma, neuronal) 0.312827
FLNA filamin A, alpha 0.303781
ASXL1 additional sex combs like transcriptional regulator 1 0.302698
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.296571
ZFX zinc finger protein, X-linked 0.296211
CCNB2 cyclin B2 0.294772
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.294053
AANAT aralkylamine N-acetyltransferase 0.291898
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.287235
HDGF hepatoma-derived growth factor 0.280439
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.279367
UBE2C ubiquitin-conjugating enzyme E2C 0.27794
ZMYND10 zinc finger, MYND-type containing 10 0.272953
DAPK1 death-associated protein kinase 1 0.269753
CUTA cutA divalent cation tolerance homolog (E. coli) 0.268687
GBA glucosidase, beta, acid 0.267267
TSC2 tuberous sclerosis 2 0.267267
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 0.266558
CD1C CD1c molecule 0.262306
CGB7 chorionic gonadotropin, beta polypeptide 7 0.259477
HSPA8 heat shock 70kDa protein 8 0.258417
CGB5 chorionic gonadotropin, beta polypeptide 5 0.258064
GDF9 growth differentiation factor 9 0.255946
MCAM melanoma cell adhesion molecule 0.255594
PLK1 polo-like kinase 1 0.254183
LMAN1 lectin, mannose-binding, 1 0.253127
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.246448
NDRG2 NDRG family member 2 0.245396
ANXA3 annexin A3 0.245046
METAP2 methionyl aminopeptidase 2 0.243995
PDIA3 protein disulfide isomerase family A, member 3 0.243995
PEG10 paternally expressed 10 0.241546
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.241196
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase 0.23945
RUNX3 runt-related transcription factor 3 0.238752
CGB chorionic gonadotropin, beta polypeptide 0.235616
CGB8 chorionic gonadotropin, beta polypeptide 8 0.235268
PPY pancreatic polypeptide 0.23353
TSG101 tumor susceptibility 101 0.230063
GGT2 gamma-glutamyltransferase 2 0.225917
C2 complement component 2 0.223165
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.220081
SYP synaptophysin 0.21974
CHPF chondroitin polymerizing factor 0.219057
MSH2 mutS homolog 2 0.210925
EPCAM epithelial cell adhesion molecule 0.203933
S100A10 S100 calcium binding protein A10 0.201962
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.194548
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.1936
SOX4 SRY (sex determining region Y)-box 4 0.192657
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.192657
EZR ezrin 0.192657
TERT telomerase reverse transcriptase 0.192344
GLI1 GLI family zinc finger 1 0.191719
CDC6 cell division cycle 6 0.189244
BBC3 BCL2 binding component 3 0.187415
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.187113
BSG basigin (Ok blood group) 0.185612
BIRC5 baculoviral IAP repeat containing 5 0.185313
HHAT hedgehog acyltransferase 0.177576
MAGEC1 melanoma antigen family C1 0.177301
HDAC1 histone deacetylase 1 0.176757
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.176757
GLUD1 glutamate dehydrogenase 1 0.174354
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.170789
DROSHA drosha, ribonuclease type III 0.165655
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.163729
BTNL2 butyrophilin-like 2 0.161331
PROM1 prominin 1 0.160761
DLL4 delta-like 4 (Drosophila) 0.160387
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.158778
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.158266
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.157765
FGF4 fibroblast growth factor 4 0.14428
CTSD cathepsin D 0.142135
CD86 CD86 molecule 0.140096
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 0.136095
NKX2-1 NK2 homeobox 1 0.135646
AMY2A amylase, alpha 2A (pancreatic) 0.135612
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.13559
BMPR1A bone morphogenetic protein receptor, type IA 0.135567
KRT8 keratin 8, type II 0.135452
MCM2 minichromosome maintenance complex component 2 0.134627
S1PR1 sphingosine-1-phosphate receptor 1 0.133673
S100P S100 calcium binding protein P 0.133603
ARG1 arginase 1 0.132828
ANKRD11 ankyrin repeat domain 11 0.131626
TYK2 tyrosine kinase 2 0.131105
PNLIP pancreatic lipase 0.130616
MCM7 minichromosome maintenance complex component 7 0.130383
EPHA2 EPH receptor A2 0.129182
WAPAL wings apart-like homolog (Drosophila) 0.12916
LYZ lysozyme 0.127824
ANXA1 annexin A1 0.126738
DICER1 dicer 1, ribonuclease type III 0.126738
ANXA2 annexin A2 0.12428
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.123615
XPC xeroderma pigmentosum, complementation group C 0.123615
CD9 CD9 molecule 0.123582
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 0.123256
CALR calreticulin 0.120255
SELE selectin E 0.119587
NFE2L2 nuclear factor, erythroid 2-like 2 0.119104