gap junction Gene Set

Dataset KEGG Pathways
Category structural or functional annotations
Type pathway
Description A cell-cell junction that is composed of an array of small channels that permit small molecules to pass from one cell to another. At gap junctions, the membranes of two adjacent cells are separated by a uniform narrow gap of about 2-4 nm that is spanned by channel-forming proteins called connexins, which form hexagonal tubes called connexons. (Gene Ontology, GO_0005921)
External Link http://www.genome.jp/kegg/pathway/hsa/hsa04540.html
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Genes

90 proteins participating in the gap junction pathway from the KEGG Pathways dataset.

Symbol Name
ADCY1 adenylate cyclase 1 (brain)
ADCY2 adenylate cyclase 2 (brain)
ADCY3 adenylate cyclase 3
ADCY4 adenylate cyclase 4
ADCY5 adenylate cyclase 5
ADCY6 adenylate cyclase 6
ADCY7 adenylate cyclase 7
ADCY8 adenylate cyclase 8 (brain)
ADCY9 adenylate cyclase 9
ADRB1 adrenoceptor beta 1
CSNK1D casein kinase 1, delta
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
GJA1 gap junction protein, alpha 1, 43kDa
GJD2 gap junction protein, delta 2, 36kDa
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNAS GNAS complex locus
GRB2 growth factor receptor-bound protein 2
GRM1 glutamate receptor, metabotropic 1
GRM5 glutamate receptor, metabotropic 5
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
GUCY2C guanylate cyclase 2C
GUCY2D guanylate cyclase 2D, membrane (retina-specific)
GUCY2F guanylate cyclase 2F, retinal
HRAS Harvey rat sarcoma viral oncogene homolog
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KRAS Kirsten rat sarcoma viral oncogene homolog
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
NPR1 natriuretic peptide receptor 1
NPR2 natriuretic peptide receptor 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFC platelet derived growth factor C
PDGFD platelet derived growth factor D
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCB2 phospholipase C, beta 2
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCB4 phospholipase C, beta 4
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PRKCA protein kinase C, alpha
PRKCG protein kinase C, gamma
PRKG1 protein kinase, cGMP-dependent, type I
PRKG2 protein kinase, cGMP-dependent, type II
PRKX protein kinase, X-linked
PRKY protein kinase, Y-linked, pseudogene
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
SOS1 son of sevenless homolog 1 (Drosophila)
SOS2 son of sevenless homolog 2 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TJP1 tight junction protein 1
TUBA1A tubulin, alpha 1a
TUBA1B tubulin, alpha 1b
TUBA1C tubulin, alpha 1c
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
TUBA3E tubulin, alpha 3e
TUBA4A tubulin, alpha 4a
TUBA8 tubulin, alpha 8
TUBAL3 tubulin, alpha-like 3
TUBB tubulin, beta class I
TUBB1 tubulin, beta 1 class VI
TUBB2A tubulin, beta 2A class IIa
TUBB2B tubulin, beta 2B class IIb
TUBB3 tubulin, beta 3 class III
TUBB6 tubulin, beta 6 class V
TUBB8 tubulin, beta 8 class VIII