gas gangrene Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A commensal bacterial infectious disease that results_in infection, located_in muscle tissue, has_material_basis_in Clostridium perfringens, which produce gas that becomes trapped in the infected tissue. Gas gangrene usually develops after injuries or surgery. The infection has_symptom large blisters, has_symptom pain in the infected area, has_symptom myonecrosis, has_symptom gas production, and has_symptom sepsis. (Human Disease Ontology, DOID_9159)
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Genes

98 genes co-occuring with the disease gas gangrene in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PLA2G1B phospholipase A2, group IB (pancreas) 1.80021
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.5423
TMC4 transmembrane channel-like 4 1.35376
CASQ2 calsequestrin 2 (cardiac muscle) 1.29003
DMD dystrophin 1.28697
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 1.27475
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 1.27388
TNNT2 troponin T type 2 (cardiac) 1.21695
CPE carboxypeptidase E 1.19273
RBM12 RNA binding motif protein 12 1.17851
TNNI3 troponin I type 3 (cardiac) 1.1635
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 1.07992
PLA2G10 phospholipase A2, group X 0.819206
SLBP stem-loop binding protein 0.812642
MYOM1 myomesin 1 0.801974
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.798282
MB myoglobin 0.776568
RORA RAR-related orphan receptor A 0.751271
IL4I1 interleukin 4 induced 1 0.716425
MYOG myogenin (myogenic factor 4) 0.685091
PRF1 perforin 1 (pore forming protein) 0.684692
CRP C-reactive protein, pentraxin-related 0.671527
CCDC130 coiled-coil domain containing 130 0.66914
ACSL1 acyl-CoA synthetase long-chain family member 1 0.664372
SRL sarcalumenin 0.651694
CTNS cystinosin, lysosomal cystine transporter 0.642221
MYOD1 myogenic differentiation 1 0.640251
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.637102
UTRN utrophin 0.630813
SNTA1 syntrophin, alpha 1 0.6214
CPA1 carboxypeptidase A1 (pancreatic) 0.621008
ATAD3C ATPase family, AAA domain containing 3C 0.613965
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.60342
LAMP1 lysosomal-associated membrane protein 1 0.581606
FANCL Fanconi anemia, complementation group L 0.578494
DNAH8 dynein, axonemal, heavy chain 8 0.574605
FN1 fibronectin 1 0.555956
ACACB acetyl-CoA carboxylase beta 0.515725
CPB2 carboxypeptidase B2 (plasma) 0.485885
ENGASE endo-beta-N-acetylglucosaminidase 0.480186
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.475634
QPCT glutaminyl-peptide cyclotransferase 0.466172
WASF3 WAS protein family, member 3 0.460129
EPS15 epidermal growth factor receptor pathway substrate 15 0.458619
FKTN fukutin 0.456732
CAV3 caveolin 3 0.436778
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.436778
MIR133B microRNA 133b 0.431894
RAET1E retinoic acid early transcript 1E 0.420641
LPIN1 lipin 1 0.411657
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.407919
RSPO1 R-spondin 1 0.374068
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 0.366671
CHPF chondroitin polymerizing factor 0.364085
SP3 Sp3 transcription factor 0.363347
PRKD1 protein kinase D1 0.357446
KLK11 kallikrein-related peptidase 11 0.340906
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 0.325916
EDN1 endothelin 1 0.320817
MMP9 matrix metallopeptidase 9 0.31464
UBAP1 ubiquitin associated protein 1 0.292257
MMP2 matrix metallopeptidase 2 0.286519
GFER growth factor, augmenter of liver regeneration 0.282582
CRYGD crystallin, gamma D 0.275089
IL1B interleukin 1, beta 0.250663
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 0.246098
CAV2 caveolin 2 0.246098
PRDX6 peroxiredoxin 6 0.243295
CSN1S1 casein alpha s1 0.239101
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 0.237357
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 0.230409
CTSS cathepsin S 0.225229
CPN1 carboxypeptidase N, polypeptide 1 0.220081
TSPO translocator protein (18kDa) 0.216672
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.208579
TNF tumor necrosis factor 0.207578
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.198064
VAV1 vav 1 guanine nucleotide exchange factor 0.184128
CAV1 caveolin 1, caveolae protein, 22kDa 0.180084
GSTA3 glutathione S-transferase alpha 3 0.17896
GSTA2 glutathione S-transferase alpha 2 0.177851
MMP25 matrix metallopeptidase 25 0.177301
HMGB1 high mobility group box 1 0.177301
GSTA4 glutathione S-transferase alpha 4 0.177029
CLEC3A C-type lectin domain family 3, member A 0.175947
CPB1 carboxypeptidase B1 (tissue) 0.174354
GSTA1 glutathione S-transferase alpha 1 0.173057
CLEC2B C-type lectin domain family 2, member B 0.172544
A1BG alpha-1-B glycoprotein 0.170299
SOD2 superoxide dismutase 2, mitochondrial 0.169091
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 0.162505
MRC1 mannose receptor, C type 1 0.161716
RHO rhodopsin 0.160948
PDGFB platelet-derived growth factor beta polypeptide 0.160574
CLEC10A C-type lectin domain family 10, member A 0.159124
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.158951
LAMP2 lysosomal-associated membrane protein 2 0.158266
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.158097