gastroenteritis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A gastrointestinal system infectious disease that involves inflammation of the lining of the stomach and small and large intestines, which is caused by viruses, bacteria, or parasites. Chemicals and drugs also cause gastroenteritis. The symptoms include diarrhea, loss of appetite, nausea, vomiting, cramps, and discomfort in the abdomen. (Human Disease Ontology, DOID_2326)
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Genes

249 genes co-occuring with the disease gastroenteritis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
HBG1 hemoglobin, gamma A 2.39332
PDGFB platelet-derived growth factor beta polypeptide 2.09806
ICT1 immature colon carcinoma transcript 1 1.9652
SH2D3A SH2 domain containing 3A 1.91407
SH2D3C SH2 domain containing 3C 1.83138
ZNF185 zinc finger protein 185 (LIM domain) 1.7709
CD79A CD79a molecule, immunoglobulin-associated alpha 1.6936
SEMG1 semenogelin I 1.53524
PPT2 palmitoyl-protein thioesterase 2 1.5326
CDSN corneodesmosin 1.4443
SUMF2 sulfatase modifying factor 2 1.41183
TFF3 trefoil factor 3 (intestinal) 1.32061
PLXNA1 plexin A1 1.28654
FUT2 fucosyltransferase 2 (secretor status included) 1.25733
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 1.2395
OR1L1 olfactory receptor, family 1, subfamily L, member 1 1.22735
PHB2 prohibitin 2 1.20266
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 1.17636
TRH thyrotropin-releasing hormone 1.14178
LCT lactase 1.08034
STX2 syntaxin 2 1.07026
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 1.05723
PER1 period circadian clock 1 1.03788
NONO non-POU domain containing, octamer-binding 1.03156
EPGN epithelial mitogen 1.0244
CRP C-reactive protein, pentraxin-related 0.989379
NBPF1 neuroblastoma breakpoint family, member 1 0.97212
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin 0.942443
STX1A syntaxin 1A (brain) 0.890898
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 0.890488
CALCOCO2 calcium binding and coiled-coil domain 2 0.84544
ANPEP alanyl (membrane) aminopeptidase 0.826178
ITM2B integral membrane protein 2B 0.822077
CERS4 ceramide synthase 4 0.792951
ALLC allantoicase 0.786394
ALB albumin 0.779023
PRRT2 proline-rich transmembrane protein 2 0.772479
LTF lactotransferrin 0.752492
PNPT1 polyribonucleotide nucleotidyltransferase 1 0.750864
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.744766
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.744766
TLR5 toll-like receptor 5 0.735027
CDV3 CDV3 homolog (mouse) 0.728143
SOS1 son of sevenless homolog 1 (Drosophila) 0.721673
PYGO1 pygopus family PHD finger 1 0.720865
CD4 CD4 molecule 0.715618
CXCL8 chemokine (C-X-C motif) ligand 8 0.675112
MGARP mitochondria-localized glutamic acid-rich protein 0.671527
CES1P1 carboxylesterase 1 pseudogene 1 0.663578
IL5 interleukin 5 0.662784
TECR trans-2,3-enoyl-CoA reductase 0.658422
ALPPL2 alkaline phosphatase, placental-like 2 0.650903
ALPP alkaline phosphatase, placental 0.650113
ALPL alkaline phosphatase, liver/bone/kidney 0.649718
GPR161 G protein-coupled receptor 161 0.646559
OR13F1 olfactory receptor, family 13, subfamily F, member 1 0.639857
TTK TTK protein kinase 0.636708
RER1 retention in endoplasmic reticulum sorting receptor 1 0.634349
CAT catalase 0.631598
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 0.626495
TRIM68 tripartite motif containing 68 0.622183
LALBA lactalbumin, alpha- 0.622183
LIPT1 lipoyltransferase 1 0.618268
RSPH1 radial spoke head 1 homolog (Chlamydomonas) 0.612011
BOLA3 bolA family member 3 0.611229
CPE carboxypeptidase E 0.59952
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic) 0.595623
SI sucrase-isomaltase (alpha-glucosidase) 0.587054
ZNF77 zinc finger protein 77 0.580439
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 0.579661
STAT1 signal transducer and activator of transcription 1, 91kDa 0.550522
CHRDL1 chordin-like 1 0.546256
GYPA glycophorin A (MNS blood group) 0.545868
FLG2 filaggrin family member 2 0.544318
PGLYRP3 peptidoglycan recognition protein 3 0.539667
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like 0.535409
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 0.529222
AADACL3 arylacetamide deacetylase-like 3 0.51919
GP2 glycoprotein 2 (zymogen granule membrane) 0.512648
CSN1S1 casein alpha s1 0.51188
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 0.508808
C3ORF18 chromosome 3 open reading frame 18 0.504207
RAB32 RAB32, member RAS oncogene family 0.503058
IFI30 interferon, gamma-inducible protein 30 0.497703
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 0.497321
CAPN8 calpain 8 0.495793
CD248 CD248 molecule, endosialin 0.479047
DLD dihydrolipoamide dehydrogenase 0.470711
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 0.470332
KCNK2 potassium channel, two pore domain subfamily K, member 2 0.466928
ALG6 ALG6, alpha-1,3-glucosyltransferase 0.466928
RNASE3 ribonuclease, RNase A family, 3 0.465416
CLDN3 claudin 3 0.461261
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 0.458996
RGR retinal G protein coupled receptor 0.438658
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.43753
CWC15 CWC15 spliceosome-associated protein 0.436778
F11R F11 receptor 0.436402
GADD45G growth arrest and DNA-damage-inducible, gamma 0.430393
OCLN occludin 0.423265
TJP1 tight junction protein 1 0.42214
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 0.419892
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.411657
CLDN1 claudin 1 0.409414
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.409414
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.408666
NFU1 NFU1 iron-sulfur cluster scaffold 0.406425
MRAP melanocortin 2 receptor accessory protein 0.406425
EEA1 early endosome antigen 1 0.404184
RNF112 ring finger protein 112 0.403064
IRGM immunity-related GTPase family, M 0.402318
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.396353
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 0.396353
CLDN7 claudin 7 0.395608
SULT1A4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 0.393001
F2 coagulation factor II (thrombin) 0.391513
PTBP1 polypyrimidine tract binding protein 1 0.390397
CCL4 chemokine (C-C motif) ligand 4 0.389653
EMC3 ER membrane protein complex subunit 3 0.385936
IFNA1 interferon, alpha 1 0.382594
GAS2 growth arrest-specific 2 0.38111
CDC5L cell division cycle 5-like 0.380739
IGHV1-2 immunoglobulin heavy variable 1-2 0.376661
TNF tumor necrosis factor 0.371847
IL1B interleukin 1, beta 0.371107
THAP3 THAP domain containing, apoptosis associated protein 3 0.370737
FIP1L1 factor interacting with PAPOLA and CPSF1 0.368518
LIAS lipoic acid synthetase 0.360764
CCL4L2 chemokine (C-C motif) ligand 4-like 2 0.356709
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.353763
FAM3C family with sequence similarity 3, member C 0.35082
CCL4L1 chemokine (C-C motif) ligand 4-like 1 0.350084
TLR4 toll-like receptor 4 0.348246
SAV1 salvador family WW domain containing protein 1 0.348246
SIVA1 SIVA1, apoptosis-inducing factor 0.347879
IL6 interleukin 6 0.347511
TMEM70 transmembrane protein 70 0.346409
GAST gastrin 0.342739
IL10 interleukin 10 0.336876
GMDS GDP-mannose 4,6-dehydratase 0.335778
HMGA2 high mobility group AT-hook 2 0.332852
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 0.331025
CSN3 casein kappa 0.33066
CAMP cathelicidin antimicrobial peptide 0.329565
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.328834
DSTN destrin (actin depolymerizing factor) 0.328469
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.317909
HTRA1 HtrA serine peptidase 1 0.313915
MUC13 mucin 13, cell surface associated 0.309566
PRRC2A proline-rich coiled-coil 2A 0.308842
PARP14 poly (ADP-ribose) polymerase family, member 14 0.305587
PYY peptide YY 0.302337
TXNL4B thioredoxin-like 4B 0.301976
MXD4 MAX dimerization protein 4 0.300894
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 0.300173
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.297291
NR1D1 nuclear receptor subfamily 1, group D, member 1 0.296571
SACK1H scaffolding CK1 anchoring protein H 0.296211
MYLK3 myosin light chain kinase 3 0.292257
NLRP2 NLR family, pyrin domain containing 2 0.290821
ATAD3C ATPase family, AAA domain containing 3C 0.287952
GUSB glucuronidase, beta 0.285802
LZTS1 leucine zipper, putative tumor suppressor 1 0.285444
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) 0.284728
TLR3 toll-like receptor 3 0.284013
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 0.279011
CNTN5 contactin 5 0.27687
SOD2 superoxide dismutase 2, mitochondrial 0.270819
CCL20 chemokine (C-C motif) ligand 20 0.268687
PNN pinin, desmosome associated protein 0.267622
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.267622
KRT75 keratin 75, type II 0.261599
MUC2 mucin 2, oligomeric mucus/gel-forming 0.260538
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 0.259477
MED28 mediator complex subunit 28 0.258417
HIST1H1A histone cluster 1, H1a 0.257005
CLDN8 claudin 8 0.255241
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 0.254183
NTSR1 neurotensin receptor 1 (high affinity) 0.252774
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 0.251718
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 0.248905
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 0.248554
INS insulin 0.247501
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.246098
ICK intestinal cell (MAK-like) kinase 0.245396
PPT1 palmitoyl-protein thioesterase 1 0.245046
EPRS glutamyl-prolyl-tRNA synthetase 0.244345
TMEM245 transmembrane protein 245 0.239799
PHB prohibitin 0.235268
GGT2 gamma-glutamyltransferase 2 0.23492
F3 coagulation factor III (thromboplastin, tissue factor) 0.231102
CDON cell adhesion associated, oncogene regulated 0.229716
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.229716
CKM creatine kinase, muscle 0.228679
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 0.228333
GLB1 galactosidase, beta 1 0.227642
IRF7 interferon regulatory factor 7 0.224884
SQLE squalene epoxidase 0.224884
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.22454
PFAS phosphoribosylformylglycinamidine synthase 0.224196
IRF3 interferon regulatory factor 3 0.219398
LUM lumican 0.215992
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 0.215653
TOP3A topoisomerase (DNA) III alpha 0.215314
TLR2 toll-like receptor 2 0.211934
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.206248
PROS1 protein S (alpha) 0.206248
NME3 NME/NM23 nucleoside diphosphate kinase 3 0.205254
INSM2 insulinoma-associated 2 0.201962
CREM cAMP responsive element modulator 0.201635
AVP arginine vasopressin 0.199033
LEMD3 LEM domain containing 3 0.198386
CARD8 caspase recruitment domain family, member 8 0.197742
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.196139
CDC42 cell division cycle 42 0.194232
GIMAP5 GTPase, IMAP family member 5 0.193915
ESPN espin 0.189551
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 0.189551
MGAM maltase-glucoamylase 0.18621
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.18472
TUBA1A tubulin, alpha 1a 0.183541
EPS15 epidermal growth factor receptor pathway substrate 15 0.180937
NELFCD negative elongation factor complex member C/D 0.177301
EPX eosinophil peroxidase 0.177029
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.176485
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.174617
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 0.171785
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.171535
NLRC4 NLR family, CARD domain containing 4 0.170789
PBK PDZ binding kinase 0.170789
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.16933
ZC3H12D zinc finger CCCH-type containing 12D 0.167682
C1S complement component 1, s subcomponent 0.164359
PABPC1 poly(A) binding protein, cytoplasmic 1 0.161912
SLURP1 secreted LY6/PLAUR domain containing 1 0.161716
SELL selectin L 0.160574
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.159658
IL3 interleukin 3 0.159569
PATE1 prostate and testis expressed 1 0.15948
LITAF lipopolysaccharide-induced TNF factor 0.159302
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.147198
CCL11 chemokine (C-C motif) ligand 11 0.146354
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.145527
TGM2 transglutaminase 2 0.145135
TSLP thymic stromal lymphopoietin 0.145044
IL4 interleukin 4 0.14458
MEFV Mediterranean fever 0.143859
C5AR1 complement component 5a receptor 1 0.142485
CHAT choline O-acetyltransferase 0.142234