gata3_22922362_treg_cd4poscd25posyfppos_lof_mouse_gpl8321_gse39864 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations
Category transcriptomics
Type transcription factor perturbation
Description transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE39864
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Genes

613 genes differentially expressed following the gata3_22922362_treg_cd4poscd25posyfppos_lof_mouse_gpl8321_gse39864 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

increased expression

Symbol Name Standardized Value
PRDX4 peroxiredoxin 4 0.201839
TMEM191C transmembrane protein 191C 0.201752
PNPO pyridoxamine 5'-phosphate oxidase 0.201519
CD9 CD9 molecule 0.201301
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 0.200953
TGM2 transglutaminase 2 0.200184
LIMK1 LIM domain kinase 1 0.199323
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.198969
ZCCHC18 zinc finger, CCHC domain containing 18 0.197279
SFXN1 sideroflexin 1 0.195869
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.195274
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 0.194754
DRC1 dynein regulatory complex subunit 1 0.194591
S100A6 S100 calcium binding protein A6 0.193316
TBCD tubulin folding cofactor D 0.192961
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.192798
BAIAP3 BAI1-associated protein 3 0.19268
SLCO2A1 solute carrier organic anion transporter family, member 2A1 0.192413
COMMD5 COMM domain containing 5 0.191722
GOLIM4 golgi integral membrane protein 4 0.190508
CYHR1 cysteine/histidine-rich 1 0.190373
ASRGL1 asparaginase like 1 0.190298
RNF32 ring finger protein 32 0.188864
USF2 upstream transcription factor 2, c-fos interacting 0.18882
RALB v-ral simian leukemia viral oncogene homolog B 0.187095
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.187065
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.187065
RBBP7 retinoblastoma binding protein 7 0.186431
EMC2 ER membrane protein complex subunit 2 0.185843
CS citrate synthase 0.183779
ASS1 argininosuccinate synthase 1 0.182972
SSR4 signal sequence receptor, delta 0.182031
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.181606
URM1 ubiquitin related modifier 1 0.179077
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.178572
TPK1 thiamin pyrophosphokinase 1 0.178068
MFSD1 major facilitator superfamily domain containing 1 0.176204
FUS FUS RNA binding protein 0.176003
VDAC2 voltage-dependent anion channel 2 0.175633
LUC7L2 LUC7-like 2 (S. cerevisiae) 0.175263
EIF4B eukaryotic translation initiation factor 4B 0.175094
POLR1E polymerase (RNA) I polypeptide E, 53kDa 0.174617
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.173119
ATP9A ATPase, class II, type 9A 0.17033
TFRC transferrin receptor 0.169615
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 0.169069
G3BP2 GTPase activating protein (SH3 domain) binding protein 2 0.168585
ENO1 enolase 1, (alpha) 0.168242
PARN poly(A)-specific ribonuclease 0.167837
UFC1 ubiquitin-fold modifier conjugating enzyme 1 0.167262
TSPO translocator protein (18kDa) 0.166982
CPQ carboxypeptidase Q 0.16692
ATAD3A ATPase family, AAA domain containing 3A 0.166609
CYB5R3 cytochrome b5 reductase 3 0.16619
LMNB1 lamin B1 0.165956
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.165752
AHI1 Abelson helper integration site 1 0.164483
LIME1 Lck interacting transmembrane adaptor 1 0.16417
TCEA2 transcription elongation factor A (SII), 2 0.163717
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 0.163405
RPA1 replication protein A1, 70kDa 0.163373
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 0.16328
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 0.160459
AGFG1 ArfGAP with FG repeats 1 0.159628
CKS2 CDC28 protein kinase regulatory subunit 2 0.159519
PALM paralemmin 0.159315
RNF19B ring finger protein 19B 0.159315
RPIA ribose 5-phosphate isomerase A 0.159112
PECR peroxisomal trans-2-enoyl-CoA reductase 0.158109
CD52 CD52 molecule 0.156408
CLEC6A C-type lectin domain family 6, member A 0.155937
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) 0.154178
FAM84A family with sequence similarity 84, member A 0.15323
EPN1 epsin 1 0.151861
LTA lymphotoxin alpha 0.151405
BIK BCL2-interacting killer (apoptosis-inducing) 0.151405
PHGDH phosphoglycerate dehydrogenase 0.150824
TP53I13 tumor protein p53 inducible protein 13 0.149955
RRP1B ribosomal RNA processing 1B 0.149639
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.149608
SEPT9 septin 9 0.149608
FCGBP Fc fragment of IgG binding protein 0.149182
CD22 CD22 molecule 0.148567
NUCB2 nucleobindin 2 0.14822
SLC39A11 solute carrier family 39, member 11 0.147732
LEPROT leptin receptor overlapping transcript 0.147418
RORA RAR-related orphan receptor A 0.147324
FYN FYN proto-oncogene, Src family tyrosine kinase 0.14712
MTAP methylthioadenosine phosphorylase 0.146315
DUSP6 dual specificity phosphatase 6 0.146251
ETF1 eukaryotic translation termination factor 1 0.143508
TMEM38B transmembrane protein 38B 0.14261
MBD2 methyl-CpG binding domain protein 2 0.142579
USP36 ubiquitin specific peptidase 36 0.142405
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 0.141946
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 0.141157
COX5B cytochrome c oxidase subunit Vb 0.140354
TMEM219 transmembrane protein 219 0.13867
HLA-DOA major histocompatibility complex, class II, DO alpha 0.138212
EIF4A1 eukaryotic translation initiation factor 4A1 0.13648
PGK1 phosphoglycerate kinase 1 0.135648
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 0.135271
PPIC peptidylprolyl isomerase C (cyclophilin C) 0.134609
CTPS1 CTP synthase 1 0.133413
HPCAL1 hippocalcin-like 1 0.133334
DNASE1L1 deoxyribonuclease I-like 1 0.133067
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 0.130619
VWA8 von Willebrand factor A domain containing 8 0.130572
CACNG6 calcium channel, voltage-dependent, gamma subunit 6 0.129959
DPP4 dipeptidyl-peptidase 4 0.128549
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.128299
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 0.124701
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.124155
ALDOC aldolase C, fructose-bisphosphate 0.124046
CD300A CD300a molecule 0.12261
C11ORF31 chromosome 11 open reading frame 31 0.122298
QDPR quinoid dihydropteridine reductase 0.122267
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.121815
PPCDC phosphopantothenoylcysteine decarboxylase 0.121473
PANX1 pannexin 1 0.121099
RIPK3 receptor-interacting serine-threonine kinase 3 0.121006
HAUS3 HAUS augmin-like complex, subunit 3 0.120897
SLAMF6 SLAM family member 6 0.119981
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.117728
MYB v-myb avian myeloblastosis viral oncogene homolog 0.117078
SLC19A1 solute carrier family 19 (folate transporter), member 1 0.115717
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.114835
SPPL2A signal peptide peptidase like 2A 0.112538
GNG10 guanine nucleotide binding protein (G protein), gamma 10 0.111214
ELOVL3 ELOVL fatty acid elongase 3 0.107841
FLNA filamin A, alpha 0.106328
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.104988
SLC12A8 solute carrier family 12, member 8 0.10409
FOXK2 forkhead box K2 0.103224
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.102451
TCF19 transcription factor 19 0.099971
TIAM1 T-cell lymphoma invasion and metastasis 1 0.099473
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.098539
LRMP lymphoid-restricted membrane protein 0.097158
RPL28 ribosomal protein L28 0.096273
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.095375
ACSL1 acyl-CoA synthetase long-chain family member 1 0.094299
ZGLP1 zinc finger, GATA-like protein 1 0.094195
BMP2K BMP2 inducible kinase 0.093614
RTN4 reticulon 4 0.092795
GRK6 G protein-coupled receptor kinase 6 0.091295
PLAC8 placenta-specific 8 0.091265
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 0.090614
CRYBG3 beta-gamma crystallin domain containing 3 0.090244
AK2 adenylate kinase 2 0.08834
CXCL10 chemokine (C-X-C motif) ligand 10 0.088149
DOC2B double C2-like domains, beta 0.088149
WBSCR27 Williams Beuren syndrome chromosome region 27 0.08393
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 0.082547
POLR1D polymerase (RNA) I polypeptide D, 16kDa 0.082489
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.081663
LAMC3 laminin, gamma 3 0.081474
RILPL2 Rab interacting lysosomal protein-like 2 0.080924
RAP1A RAP1A, member of RAS oncogene family 0.08049
ITGB3BP integrin beta 3 binding protein (beta3-endonexin) 0.07899
MRPL28 mitochondrial ribosomal protein L28 0.078717
MED16 mediator complex subunit 16 0.078559
S100A4 S100 calcium binding protein A4 0.07764
ZNF622 zinc finger protein 622 0.077568
NDUFA11 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa 0.077224
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.076222
KIF1B kinesin family member 1B 0.073716
TOP2A topoisomerase (DNA) II alpha 170kDa 0.073631
RECK reversion-inducing-cysteine-rich protein with kazal motifs 0.072879
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 0.072002
ARID5A AT rich interactive domain 5A (MRF1-like) 0.070523
IFNA7 interferon, alpha 7 0.070157
MRPS5 mitochondrial ribosomal protein S5 0.067623
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 0.066718
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 0.065801
ERP44 endoplasmic reticulum protein 44 0.065496
KLHL5 kelch-like family member 5 0.062791
JDP2 Jun dimerization protein 2 0.062516
NCAM1 neural cell adhesion molecule 1 0.060082
SLC39A6 solute carrier family 39 (zinc transporter), member 6 0.060028
AURKB aurora kinase B 0.059225
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 0.058803
THY1 Thy-1 cell surface antigen 0.058776
PNP purine nucleoside phosphorylase 0.058749
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.056722
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.054658
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 0.054072
VTI1A vesicle transport through interaction with t-SNAREs 1A 0.053632
AEBP2 AE binding protein 2 0.052491
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) 0.052374
PTCH1 patched 1 0.051414
WLS wntless Wnt ligand secretion mediator 0.051414
TMEM2 transmembrane protein 2 0.051297
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.050805
MRPL48 mitochondrial ribosomal protein L48 0.050514
CCDC53 coiled-coil domain containing 53 0.049905
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 0.049876
GAS5 growth arrest-specific 5 (non-protein coding) 0.049849
SMDT1 single-pass membrane protein with aspartate-rich tail 1 0.048376
CLCN5 chloride channel, voltage-sensitive 5 0.04637
TPT1 tumor protein, translationally-controlled 1 0.046171
GMPPA GDP-mannose pyrophosphorylase A 0.045117
DUSP1 dual specificity phosphatase 1 0.042542
CLEC4G C-type lectin domain family 4, member G 0.042345
S100A1 S100 calcium binding protein A1 0.042036
PGLS 6-phosphogluconolactonase 0.041476
TLE3 transducin-like enhancer of split 3 0.040915
TXNDC17 thioredoxin domain containing 17 0.039351
SOCS2 suppressor of cytokine signaling 2 0.036009
TRAK1 trafficking protein, kinesin binding 1 0.035789
IL6 interleukin 6 0.034832
ADSS adenylosuccinate synthase 0.034587
M6PR mannose-6-phosphate receptor (cation dependent) 0.03366
ATPIF1 ATPase inhibitory factor 1 0.032737
TSPAN31 tetraspanin 31 0.032169
KSR1 kinase suppressor of ras 1 0.031227
RAB37 RAB37, member RAS oncogene family 0.031038
C1QBP complement component 1, q subcomponent binding protein 0.030499
MBIP MAP3K12 binding inhibitory protein 1 0.029829
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.028604
RACGAP1 Rac GTPase activating protein 1 0.027699
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1 0.027593
UBE2A ubiquitin-conjugating enzyme E2A 0.026614
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.024224
RNF43 ring finger protein 43 0.023652
ENDOD1 endonuclease domain containing 1 0.0236
COMTD1 catechol-O-methyltransferase domain containing 1 0.022509
ABAT 4-aminobutyrate aminotransferase 0.022483
CDK7 cyclin-dependent kinase 7 0.021577
SCG5 secretogranin V 0.02065
ACTG2 actin, gamma 2, smooth muscle, enteric 0.01955
RXRA retinoid X receptor, alpha 0.019498
DNAJC27 DnaJ (Hsp40) homolog, subfamily C, member 27 0.019293
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.018732
OGFRL1 opioid growth factor receptor-like 1 0.01807
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia) 0.017564
QARS glutaminyl-tRNA synthetase 0.016452
EDIL3 EGF-like repeats and discoidin I-like domains 3 0.01567
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 0.014222
CDC6 cell division cycle 6 0.012681
CXCR5 chemokine (C-X-C motif) receptor 5 0.012385
LGALS1 lectin, galactoside-binding, soluble, 1 0.011992
PCCB propionyl CoA carboxylase, beta polypeptide 0.011525
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 0.011205
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 0.011155
LARP1B La ribonucleoprotein domain family, member 1B 0.009736
EBPL emopamil binding protein-like 0.009178
ART3 ADP-ribosyltransferase 3 0.008474
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 0.00845
ITGA6 integrin, alpha 6 0.008256
CD5L CD5 molecule-like 0.00669
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 0.006427
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2 0.005518
PRSS16 protease, serine, 16 (thymus) 0.004755
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 0.004661
C9ORF85 chromosome 9 open reading frame 85 0.004614
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 0.001278

decreased expression

Symbol Name Standardized Value
ITM2A integral membrane protein 2A -1.18677
TLE4 transducin-like enhancer of split 4 -1.1777
TNXB tenascin XB -1.17613
TRIO trio Rho guanine nucleotide exchange factor -1.17355
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase -1.17238
ITK IL2-inducible T-cell kinase -1.17192
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -1.17052
PRODH proline dehydrogenase (oxidase) 1 -1.16293
WNT3 wingless-type MMTV integration site family, member 3 -1.16277
DDIT3 DNA-damage-inducible transcript 3 -1.15128
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein -1.14682
TLR7 toll-like receptor 7 -1.14096
RBL2 retinoblastoma-like 2 -1.13769
LZTR1 leucine-zipper-like transcription regulator 1 -1.13339
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -1.13234
YTHDC1 YTH domain containing 1 -1.11651
SPP1 secreted phosphoprotein 1 -1.10989
ZNF292 zinc finger protein 292 -1.10444
GNG12 guanine nucleotide binding protein (G protein), gamma 12 -1.10311
IPO9 importin 9 -1.10282
ZNF574 zinc finger protein 574 -1.08947
TTC3 tetratricopeptide repeat domain 3 -1.0875
FOXO1 forkhead box O1 -1.0828
PRPF4B pre-mRNA processing factor 4B -1.08086
PRPF38B pre-mRNA processing factor 38B -1.08072
AGTPBP1 ATP/GTP binding protein 1 -1.07524
SOX4 SRY (sex determining region Y)-box 4 -1.07234
CNN3 calponin 3, acidic -1.06642
PRKD3 protein kinase D3 -1.06142
CLCC1 chloride channel CLIC-like 1 -1.06086
SMC4 structural maintenance of chromosomes 4 -1.04998
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila) -1.04984
MAP3K3 mitogen-activated protein kinase kinase kinase 3 -1.0474
TKTL1 transketolase-like 1 -1.04375
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 -1.04005
VPREB1 pre-B lymphocyte 1 -1.03594
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 -1.03204
ENG endoglin -1.02406
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -1.02126
SH2D1A SH2 domain containing 1A -1.01539
SERP1 stress-associated endoplasmic reticulum protein 1 -1.0116
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) -0.998285
TYRO3 TYRO3 protein tyrosine kinase -0.997892
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.99418
FOXP1 forkhead box P1 -0.99405
MACF1 microtubule-actin crosslinking factor 1 -0.993143
SMC6 structural maintenance of chromosomes 6 -0.989792
KLF3 Kruppel-like factor 3 (basic) -0.980891
SELL selectin L -0.97904
DPH2 DPH2 homolog (S. cerevisiae) -0.978658
NRP1 neuropilin 1 -0.978213
TBATA thymus, brain and testes associated -0.964379
CAMK4 calcium/calmodulin-dependent protein kinase IV -0.96232
FAM160B1 family with sequence similarity 160, member B1 -0.957986
JADE1 jade family PHD finger 1 -0.951846
CD7 CD7 molecule -0.947431
WDR26 WD repeat domain 26 -0.947066
FAM118B family with sequence similarity 118, member B -0.945545
DGCR6 DiGeorge syndrome critical region gene 6 -0.944513
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 -0.943968
IFT80 intraflagellar transport 80 -0.93838
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.933144
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -0.927912
HIST3H2A histone cluster 3, H2a -0.927493
ETAA1 Ewing tumor-associated antigen 1 -0.927374
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 -0.921675
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) -0.915643
TASP1 taspase, threonine aspartase, 1 -0.911045
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.894946
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 -0.888533
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B -0.881961
ETNK1 ethanolamine kinase 1 -0.881462
SAMHD1 SAM domain and HD domain 1 -0.87535
KMT2A lysine (K)-specific methyltransferase 2A -0.871645
METTL3 methyltransferase like 3 -0.870553
WNT8B wingless-type MMTV integration site family, member 8B -0.868432
ORC4 origin recognition complex, subunit 4 -0.864865
ELOVL1 ELOVL fatty acid elongase 1 -0.862128
AIRN antisense of IGF2R non-protein coding RNA -0.859675
OXR1 oxidation resistance 1 -0.851559
FBXL12 F-box and leucine-rich repeat protein 12 -0.849251
RCN2 reticulocalbin 2, EF-hand calcium binding domain -0.840256
MFN1 mitofusin 1 -0.839225
SIRT1 sirtuin 1 -0.837787
IFI16 interferon, gamma-inducible protein 16 -0.837325
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -0.831971
TMED7 transmembrane emp24 protein transport domain containing 7 -0.830395
UBE2H ubiquitin-conjugating enzyme E2H -0.829989
SRSF7 serine/arginine-rich splicing factor 7 -0.829534
SERINC3 serine incorporator 3 -0.827312
NADK NAD kinase -0.8239
NFX1 nuclear transcription factor, X-box binding 1 -0.81605
GLG1 golgi glycoprotein 1 -0.812317
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 -0.775376
PAPOLA poly(A) polymerase alpha -0.775285
TLK2 tousled-like kinase 2 -0.770537
PCDHA10 protocadherin alpha 10 -0.76406
ZBTB16 zinc finger and BTB domain containing 16 -0.761185
ADCY6 adenylate cyclase 6 -0.761097
MEF2A myocyte enhancer factor 2A -0.754576
REV1 REV1, polymerase (DNA directed) -0.750295
TGFBR1 transforming growth factor, beta receptor 1 -0.746737
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 -0.737484
RBMS2 RNA binding motif, single stranded interacting protein 2 -0.737484
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.733075
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 -0.732166
BCAP31 B-cell receptor-associated protein 31 -0.729491
STXBP2 syntaxin binding protein 2 -0.728507
LEF1 lymphoid enhancer-binding factor 1 -0.728221
CCDC71L coiled-coil domain containing 71-like -0.720598
CD247 CD247 molecule -0.719715
PEX6 peroxisomal biogenesis factor 6 -0.716999
CSPP1 centrosome and spindle pole associated protein 1 -0.706656
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B -0.705531
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.705105
CHTOP chromatin target of PRMT1 -0.704951
RFTN2 raftlin family member 2 -0.702906
IFNAR1 interferon (alpha, beta and omega) receptor 1 -0.70183
SOAT1 sterol O-acyltransferase 1 -0.701141
RBM6 RNA binding motif protein 6 -0.696421
MAGT1 magnesium transporter 1 -0.696156
BRWD1 bromodomain and WD repeat domain containing 1 -0.695892
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -0.695174
NFE2L3 nuclear factor, erythroid 2-like 3 -0.69491
HAAO 3-hydroxyanthranilate 3,4-dioxygenase -0.691607
GRAMD3 GRAM domain containing 3 -0.690972
SEPT4 septin 4 -0.686336
NT5C3A 5'-nucleotidase, cytosolic IIIA -0.684569
FSIP1 fibrous sheath interacting protein 1 -0.682959
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 -0.679542
TSPAN13 tetraspanin 13 -0.677555
ZC3H10 zinc finger CCCH-type containing 10 -0.677555
ZNF638 zinc finger protein 638 -0.677158
ERC1 ELKS/RAB6-interacting/CAST family member 1 -0.673542
TTC28 tetratricopeptide repeat domain 28 -0.664914
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) -0.661122
AP2A2 adaptor-related protein complex 2, alpha 2 subunit -0.660066
HIST1H2BC histone cluster 1, H2bc -0.655729
REXO4 REX4, RNA exonuclease 4 homolog (S. cerevisiae) -0.65255
CP ceruloplasmin (ferroxidase) -0.647868
PENK proenkephalin -0.643035
ZFP2 ZFP2 zinc finger protein -0.640464
EDRF1 erythroid differentiation regulatory factor 1 -0.63142
ASB13 ankyrin repeat and SOCS box containing 13 -0.621874
PCID2 PCI domain containing 2 -0.621473
GRAMD1A GRAM domain containing 1A -0.621406
RGL3 ral guanine nucleotide dissociation stimulator-like 3 -0.618395
EYA4 EYA transcriptional coactivator and phosphatase 4 -0.618395
EIF5 eukaryotic translation initiation factor 5 -0.616741
ZW10 zw10 kinetochore protein -0.613193
GABARAPL2 GABA(A) receptor-associated protein-like 2 -0.612865
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -0.610328
PHIP pleckstrin homology domain interacting protein -0.609683
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase -0.607751
LYSMD3 LysM, putative peptidoglycan-binding, domain containing 3 -0.604106
RORC RAR-related orphan receptor C -0.601963
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae) -0.599953
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 -0.59989
ADCY9 adenylate cyclase 9 -0.599704
SET SET nuclear proto-oncogene -0.598828
MAPK14 mitogen-activated protein kinase 14 -0.595171
MRPS11 mitochondrial ribosomal protein S11 -0.589437
TBX21 T-box 21 -0.589135
UFSP1 UFM1-specific peptidase 1 (non-functional) -0.587694
PKNOX1 PBX/knotted 1 homeobox 1 -0.586378
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 -0.584709
BRE brain and reproductive organ-expressed (TNFRSF1A modulator) -0.583342
CHDH choline dehydrogenase -0.581345
NEURL1 neuralized E3 ubiquitin protein ligase 1 -0.579882
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 -0.573194
ZNF281 zinc finger protein 281 -0.56828
CNOT4 CCR4-NOT transcription complex, subunit 4 -0.568114
RNF166 ring finger protein 166 -0.566053
BICD2 bicaudal D homolog 2 (Drosophila) -0.564721
YY1 YY1 transcription factor -0.559263
SLC45A2 solute carrier family 45, member 2 -0.549256
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 -0.547443
SORCS2 sortilin-related VPS10 domain containing receptor 2 -0.546979
PJA1 praja ring finger 1, E3 ubiquitin protein ligase -0.540184
KPNA4 karyopherin alpha 4 (importin alpha 3) -0.538398
SLC27A4 solute carrier family 27 (fatty acid transporter), member 4 -0.538152
PHF1 PHD finger protein 1 -0.534558
JAK1 Janus kinase 1 -0.533058
SEPT6 septin 6 -0.530985
PTPRF protein tyrosine phosphatase, receptor type, F -0.530311
ACSS1 acyl-CoA synthetase short-chain family member 1 -0.529354
VAMP4 vesicle-associated membrane protein 4 -0.527653
KANSL2 KAT8 regulatory NSL complex subunit 2 -0.525677
CLK4 CDC-like kinase 4 -0.521369
XPO1 exportin 1 -0.520315
PFDN5 prefoldin subunit 5 -0.517417
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.515804
TOX4 TOX high mobility group box family member 4 -0.514021
IL7R interleukin 7 receptor -0.510608
CBX2 chromobox homolog 2 -0.509086
BRD8 bromodomain containing 8 -0.503361
NRIP1 nuclear receptor interacting protein 1 -0.503152
SMC5 structural maintenance of chromosomes 5 -0.500292
POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit -0.50025
AEBP1 AE binding protein 1 -0.499551
KLF7 Kruppel-like factor 7 (ubiquitous) -0.496999
USP34 ubiquitin specific peptidase 34 -0.494436
CRHR1 corticotropin releasing hormone receptor 1 -0.491953
KDM5B lysine (K)-specific demethylase 5B -0.491521
TRIM59 tripartite motif containing 59 -0.491442
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase -0.490971
SF1 splicing factor 1 -0.490431
RBM14 RNA binding motif protein 14 -0.489315
SESN3 sestrin 3 -0.485024
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 -0.482307
RNF114 ring finger protein 114 -0.481543
SRPK1 SRSF protein kinase 1 -0.478102
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 -0.474893
FAM104A family with sequence similarity 104, member A -0.473882
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 -0.473813
YME1L1 YME1-like 1 ATPase -0.473779
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -0.47056
CSF1 colony stimulating factor 1 (macrophage) -0.47019
TSSK2 testis-specific serine kinase 2 -0.469857
OTUD5 OTU deubiquitinase 5 -0.467825
SLCO3A1 solute carrier organic anion transporter family, member 3A1 -0.467825
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta -0.46126
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 -0.460854
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6 -0.459238
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 -0.459025
MCOLN3 mucolipin 3 -0.457081
JMJD1C jumonji domain containing 1C -0.454464
RNF103 ring finger protein 103 -0.451992
RCOR1 REST corepressor 1 -0.44886
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 -0.448556
KLRG1 killer cell lectin-like receptor subfamily G, member 1 -0.445188
APOBR apolipoprotein B receptor -0.44479
REG3A regenerating islet-derived 3 alpha -0.444205
SLC31A2 solute carrier family 31 (copper transporter), member 2 -0.443001
DYNLT1 dynein, light chain, Tctex-type 1 -0.442126
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.441586
TOR1AIP2 torsin A interacting protein 2 -0.441123
TXK TXK tyrosine kinase -0.441123
RFK riboflavin kinase -0.440365
NT5C3B 5'-nucleotidase, cytosolic IIIB -0.438007
IFNG interferon, gamma -0.437022
CCNG2 cyclin G2 -0.43442
PELI1 pellino E3 ubiquitin protein ligase 1 -0.434397
RBM39 RNA binding motif protein 39 -0.432358
SLC25A51 solute carrier family 25, member 51 -0.431135
CDC37 cell division cycle 37 -0.43058
ZBTB48 zinc finger and BTB domain containing 48 -0.423617
AQP9 aquaporin 9 -0.422186
ATF7IP activating transcription factor 7 interacting protein -0.419716
SAMD11 sterile alpha motif domain containing 11 -0.070632
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 -0.069358
WDR43 WD repeat domain 43 -0.068032
LTV1 LTV1 ribosome biogenesis factor -0.066943
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 -0.066441
BCAP29 B-cell receptor-associated protein 29 -0.066269
IPO5 importin 5 -0.066217
CTSE cathepsin E -0.066009
NEK7 NIMA-related kinase 7 -0.065745
MARCKSL1 MARCKS-like 1 -0.063426
CD38 CD38 molecule -0.06339
AHNAK AHNAK nucleoprotein -0.062564
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa -0.06233
C3ORF17 chromosome 3 open reading frame 17 -0.061497
MFSD6 major facilitator superfamily domain containing 6 -0.060931
MRPS16 mitochondrial ribosomal protein S16 -0.060711
CPT1B carnitine palmitoyltransferase 1B (muscle) -0.060675
IGF2-AS IGF2 antisense RNA -0.059891
LGALSL lectin, galactoside-binding-like -0.059612
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7 -0.057434
BMP7 bone morphogenetic protein 7 -0.057226
MXD4 MAX dimerization protein 4 -0.055603
IFITM2 interferon induced transmembrane protein 2 -0.053727
DDRGK1 DDRGK domain containing 1 -0.053029
FDX1 ferredoxin 1 -0.052563
FIGNL1 fidgetin-like 1 -0.051961
IL3 interleukin 3 -0.050984
TNS1 tensin 1 -0.050039
CCNB1 cyclin B1 -0.049921
EIF3I eukaryotic translation initiation factor 3, subunit I -0.048034
RPS10 ribosomal protein S10 -0.047516
ZNF235 zinc finger protein 235 -0.047157
FABP9 fatty acid binding protein 9, testis -0.047018
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -0.046107
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 -0.045764
PITPNA phosphatidylinositol transfer protein, alpha -0.044181
NFS1 NFS1 cysteine desulfurase -0.043711
MINA MYC induced nuclear antigen -0.043445
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -0.042893
BOLA2 bolA family member 2 -0.040974
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -0.040953
CRMP1 collapsin response mediator protein 1 -0.040953
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha -0.040085
TMEM126A transmembrane protein 126A -0.038787
RALGDS ral guanine nucleotide dissociation stimulator -0.0386
PBX4 pre-B-cell leukemia homeobox 4 -0.038391
ABHD4 abhydrolase domain containing 4 -0.038119
HIPK2 homeodomain interacting protein kinase 2 -0.038056
TTC39B tetratricopeptide repeat domain 39B -0.037362
NUDT14 nudix (nucleoside diphosphate linked moiety X)-type motif 14 -0.036305
G6PC3 glucose 6 phosphatase, catalytic, 3 -0.035926
ETFA electron-transfer-flavoprotein, alpha polypeptide -0.034394
MRPL17 mitochondrial ribosomal protein L17 -0.032923
FAM98C family with sequence similarity 98, member C -0.032621
TK1 thymidine kinase 1, soluble -0.032492
PNO1 partner of NOB1 homolog (S. cerevisiae) -0.032039
PRKCB protein kinase C, beta -0.031029
DYNLT3 dynein, light chain, Tctex-type 3 -0.030921
MSH3 mutS homolog 3 -0.030512
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -0.030468
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 -0.030272
MPC1 mitochondrial pyruvate carrier 1 -0.030272
ACADL acyl-CoA dehydrogenase, long chain -0.029512
GSR glutathione reductase -0.0267
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 -0.026591
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -0.026111
STK19 serine/threonine kinase 19 -0.026045
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.025979
NUBP1 nucleotide binding protein 1 -0.025541
SIN3B SIN3 transcription regulator family member B -0.025518
PLSCR1 phospholipid scramblase 1 -0.02501
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila) -0.024834
MYO5A myosin VA (heavy chain 12, myoxin) -0.023469
VIM vimentin -0.023403
MRPL52 mitochondrial ribosomal protein L52 -0.023248
COMMD4 COMM domain containing 4 -0.022804
CREB3 cAMP responsive element binding protein 3 -0.022248
F2RL1 coagulation factor II (thrombin) receptor-like 1 -0.022093
APRT adenine phosphoribosyltransferase -0.02176
DSCAM Down syndrome cell adhesion molecule -0.021693
ETFB electron-transfer-flavoprotein, beta polypeptide -0.020651
REXO2 RNA exonuclease 2 -0.020629
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -0.019243
OTULIN OTU deubiquitinase with linear linkage specificity -0.017091
RCC1 regulator of chromosome condensation 1 -0.017024
SUMO3 small ubiquitin-like modifier 3 -0.016934
CCDC88C coiled-coil domain containing 88C -0.016552
KLHDC2 kelch domain containing 2 -0.016238
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase -0.015767
COX6C cytochrome c oxidase subunit VIc -0.015382
KIAA0232 KIAA0232 -0.015314
KRT6B keratin 6B, type II -0.015269
RRM2 ribonucleotide reductase M2 -0.013576
MYO1G myosin IG -0.011646
SEC14L1 SEC14-like 1 (S. cerevisiae) -0.0116
BLMH bleomycin hydrolase -0.011555
BLVRA biliverdin reductase A -0.01151
WIPI1 WD repeat domain, phosphoinositide interacting 1 -0.009028
CIRBP cold inducible RNA binding protein -0.007635
RSPH3 radial spoke 3 homolog (Chlamydomonas) -0.004285
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -0.00378
GCSH glycine cleavage system protein H (aminomethyl carrier) -0.003688
DENND2D DENN/MADD domain containing 2D -0.002607
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.001798
TRAPPC1 trafficking protein particle complex 1 -0.001406
PRPF19 pre-mRNA processing factor 19 -0.001383
ACP1 acid phosphatase 1, soluble -8.53E-4
Funding