gata4_16914500_e9dot5_atrioventricular_canal_lof_mouse_gpl1261_gds3663 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations
Category transcriptomics
Type transcription factor perturbation
Description transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GDS3663
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Genes

673 genes differentially expressed following the gata4_16914500_e9dot5_atrioventricular_canal_lof_mouse_gpl1261_gds3663 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

increased expression

Symbol Name Standardized Value
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 0.21835
PFKP phosphofructokinase, platelet 0.21726
GRHPR glyoxylate reductase/hydroxypyruvate reductase 0.214064
ITGA1 integrin, alpha 1 0.213353
RYR2 ryanodine receptor 2 (cardiac) 0.210296
AKAP5 A kinase (PRKA) anchor protein 5 0.208617
FAM96B family with sequence similarity 96, member B 0.208078
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.207794
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.206284
IER3 immediate early response 3 0.206154
FXYD1 FXYD domain containing ion transport regulator 1 0.205866
SMIM5 small integral membrane protein 5 0.204644
CD44 CD44 molecule (Indian blood group) 0.202043
CASQ2 calsequestrin 2 (cardiac muscle) 0.201432
WLS wntless Wnt ligand secretion mediator 0.199952
QKI QKI, KH domain containing, RNA binding 0.198778
CRY1 cryptochrome circadian clock 1 0.198616
INSL6 insulin-like 6 0.19659
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 0.195378
CAMTA1 calmodulin binding transcription activator 1 0.193819
CPE carboxypeptidase E 0.193168
MRPS24 mitochondrial ribosomal protein S24 0.192961
TNNI3 troponin I type 3 (cardiac) 0.191272
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 0.190777
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 0.189476
TRAPPC1 trafficking protein particle complex 1 0.189417
ADRBK2 adrenergic, beta, receptor kinase 2 0.188775
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.188684
EXOSC1 exosome component 1 0.188442
CXXC5 CXXC finger protein 5 0.185964
COMTD1 catechol-O-methyltransferase domain containing 1 0.185196
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 0.184649
DCAF12L1 DDB1 and CUL4 associated factor 12-like 1 0.18384
TEX9 testis expressed 9 0.183536
EDNRA endothelin receptor type A 0.183459
GADD45B growth arrest and DNA-damage-inducible, beta 0.182957
MYBPC3 myosin binding protein C, cardiac 0.181636
DIABLO diablo, IAP-binding mitochondrial protein 0.181379
TRIM68 tripartite motif containing 68 0.179905
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 0.179843
PDE8A phosphodiesterase 8A 0.178786
SYNPO2L synaptopodin 2-like 0.17659
NR2F6 nuclear receptor subfamily 2, group F, member 6 0.176559
NCEH1 neutral cholesterol ester hydrolase 1 0.174648
WRB tryptophan rich basic protein 0.173072
VNN1 vanin 1 0.168164
TSPAN4 tetraspanin 4 0.167962
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 0.166268
MITF microphthalmia-associated transcription factor 0.165705
MTCP1 mature T-cell proliferation 1 0.164107
ACTA1 actin, alpha 1, skeletal muscle 0.163654
TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast) 0.163233
ZDHHC2 zinc finger, DHHC-type containing 2 0.162438
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.161464
VCAM1 vascular cell adhesion molecule 1 0.161118
APH1A APH1A gamma secretase subunit 0.160036
PRKG1 protein kinase, cGMP-dependent, type I 0.158409
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 0.158361
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.157904
ATP5H ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d 0.157384
ANXA3 annexin A3 0.156235
NLK nemo-like kinase 0.155529
ZWINT ZW10 interacting kinetochore protein 0.152915
MMP15 matrix metallopeptidase 15 (membrane-inserted) 0.152632
MYL9 myosin, light chain 9, regulatory 0.152034
CDV3 CDV3 homolog (mouse) 0.150887
KRT8 keratin 8, type II 0.150746
CRIP1 cysteine-rich protein 1 (intestinal) 0.150177
CCDC107 coiled-coil domain containing 107 0.148913
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 0.14756
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.144153
MYLK3 myosin light chain kinase 3 0.141836
FRMD4B FERM domain containing 4B 0.140653
SAMD4A sterile alpha motif domain containing 4A 0.140401
AUP1 ancient ubiquitous protein 1 0.139992
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) 0.138244
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 0.137992
SPEG SPEG complex locus 0.13796
PDLIM5 PDZ and LIM domain 5 0.135679
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.13513
FLNB filamin B, beta 0.134152
SHROOM3 shroom family member 3 0.134011
ATPIF1 ATPase inhibitory factor 1 0.133932
PRKD3 protein kinase D3 0.133444
MRPL48 mitochondrial ribosomal protein L48 0.13222
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.12905
TRIM54 tripartite motif containing 54 0.127939
METTL1 methyltransferase like 1 0.127689
COX5B cytochrome c oxidase subunit Vb 0.126968
FASTKD1 FAST kinase domains 1 0.12689
HOPX HOP homeobox 0.126436
PAWR PRKC, apoptosis, WT1, regulator 0.125638
TFRC transferrin receptor 0.123984
NDUFB4 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa 0.123141
PHB prohibitin 0.122907
ZNF878 zinc finger protein 878 0.122595
LTA4H leukotriene A4 hydrolase 0.120897
TRDN triadin 0.120586
PDGFC platelet derived growth factor C 0.120416
ARHGAP31 Rho GTPase activating protein 31 0.119172
MPDZ multiple PDZ domain protein 0.118333
C10ORF10 chromosome 10 open reading frame 10 0.11793
CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10 0.117852
PALLD palladin, cytoskeletal associated protein 0.115856
NSD1 nuclear receptor binding SET domain protein 1 0.115113
YPEL2 yippee-like 2 (Drosophila) 0.113569
TTN titin 0.113014
EXOC7 exocyst complex component 7 0.112568
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.111752
PGD phosphogluconate dehydrogenase 0.11086
IPO11 importin 11 0.110722
TBX5 T-box 5 0.110414
PDZD11 PDZ domain containing 11 0.107795
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 0.106771
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 0.105292
SHFM1 split hand/foot malformation (ectrodactyly) type 1 0.102921
ARCN1 archain 1 0.102784
SH3GL3 SH3-domain GRB2-like 3 0.102678
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 0.102011
ETV5 ets variant 5 0.100394
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.09872
CENPP centromere protein P 0.098524
LPP LIM domain containing preferred translocation partner in lipoma 0.097548
EPAS1 endothelial PAS domain protein 1 0.097413
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial) 0.096482
SRFBP1 serum response factor binding protein 1 0.096123
LY6E lymphocyte antigen 6 complex, locus E 0.09512
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma 0.092899
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.09014
SP4 Sp4 transcription factor 0.0898
UBXN4 UBX domain protein 4 0.084513
TMEM261 transmembrane protein 261 0.084003
H2AFY2 H2A histone family, member Y2 0.082054
GATA2 GATA binding protein 2 0.082025
THBD thrombomodulin 0.081996
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 0.081677
SMPX small muscle protein, X-linked 0.080447
CRIP2 cysteine-rich protein 2 0.080447
CNN2 calponin 2 0.079048
MAPRE2 microtubule-associated protein, RP/EB family, member 2 0.078631
ANO1 anoctamin 1, calcium activated chloride channel 0.07853
FUK fucokinase 0.078401
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 0.076522
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa 0.075408
PIGO phosphatidylinositol glycan anchor biosynthesis, class O 0.073702
CSNK1D casein kinase 1, delta 0.072723
LARS2 leucyl-tRNA synthetase 2, mitochondrial 0.072228
BMP7 bone morphogenetic protein 7 0.070284
MARVELD1 MARVEL domain containing 1 0.070185
NCOR1 nuclear receptor corepressor 1 0.068698
NOL11 nucleolar protein 11 0.068349
DCLRE1B DNA cross-link repair 1B 0.067303
PRICKLE1 prickle homolog 1 (Drosophila) 0.066496
PKP2 plakophilin 2 0.065787
MRPS35 mitochondrial ribosomal protein S35 0.064832
EHBP1L1 EH domain binding protein 1-like 1 0.064763
FBLN1 fibulin 1 0.064735
ISCA2 iron-sulfur cluster assembly 2 0.064431
MVK mevalonate kinase 0.063576
RFC2 replication factor C (activator 1) 2, 40kDa 0.062503
PGRMC2 progesterone receptor membrane component 2 0.062255
ANAPC15 anaphase promoting complex subunit 15 0.060341
PTGR2 prostaglandin reductase 2 0.057991
RHOBTB1 Rho-related BTB domain containing 1 0.056156
HINT2 histidine triad nucleotide binding protein 2 0.055349
SARAF store-operated calcium entry-associated regulatory factor 0.054016
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 0.052891
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.050946
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.050301
DENND1B DENN/MADD domain containing 1B 0.049745
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8 0.047038
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 0.046952
SH3BGR SH3 domain binding glutamate-rich protein 0.04672
NOP10 NOP10 ribonucleoprotein 0.043786
AK7 adenylate kinase 7 0.043414
ZC3H15 zinc finger CCCH-type containing 15 0.042642
ARHGAP39 Rho GTPase activating protein 39 0.039867
MRPS6 mitochondrial ribosomal protein S6 0.039782
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 0.039754
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.039105
DRAM2 DNA-damage regulated autophagy modulator 2 0.037174
ENKUR enkurin, TRPC channel interacting protein 0.036617
TRIT1 tRNA isopentenyltransferase 1 0.036588
ETF1 eukaryotic translation termination factor 1 0.035645
COQ6 coenzyme Q6 monooxygenase 0.034594
NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 0.033078
STMN2 stathmin 2 0.032613
NCL nucleolin 0.032396
MCM7 minichromosome maintenance complex component 7 0.030785
MPND MPN domain containing 0.030542
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.028542
ACTN2 actinin, alpha 2 0.027734
CINP cyclin-dependent kinase 2 interacting protein 0.026931
CRTAP cartilage associated protein 0.025653
CISD1 CDGSH iron sulfur domain 1 0.025572
ACAA2 acetyl-CoA acyltransferase 2 0.023956
PTRH2 peptidyl-tRNA hydrolase 2 0.023378
MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) 0.022118
PTH1R parathyroid hormone 1 receptor 0.021646
COL4A2 collagen, type IV, alpha 2 0.020294
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 0.019413
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.018948
GFOD1 glucose-fructose oxidoreductase domain containing 1 0.018329
USP2 ubiquitin specific peptidase 2 0.016845
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 0.01659
PDCD5 programmed cell death 5 0.015393
MMRN2 multimerin 2 0.014458
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.014407
ATP5E ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit 0.013828
ANKHD1 ankyrin repeat and KH domain containing 1 0.012299
SRRM1 serine/arginine repetitive matrix 1 0.012199
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 0.011303
TNNT2 troponin T type 2 (cardiac) 0.010781
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 0.010657
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 0.010135
POLR2D polymerase (RNA) II (DNA directed) polypeptide D 0.008834
DUSP18 dual specificity phosphatase 18 0.008539
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase 0.008441
FOS FBJ murine osteosarcoma viral oncogene homolog 0.008295
SPTBN1 spectrin, beta, non-erythrocytic 1 0.005912
SOX7 SRY (sex determining region Y)-box 7 0.005863
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.005525
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 0.005139
SPHKAP SPHK1 interactor, AKAP domain containing 0.003988
CLUH clustered mitochondria (cluA/CLU1) homolog 0.003941
DYNLT1 dynein, light chain, Tctex-type 1 0.002487

decreased expression

Symbol Name Standardized Value
HPDL 4-hydroxyphenylpyruvate dioxygenase-like -1.36401
HES3 hes family bHLH transcription factor 3 -1.36148
ERBB3 erb-b2 receptor tyrosine kinase 3 -1.35861
KIAA0355 KIAA0355 -1.35285
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -1.34886
PLXNC1 plexin C1 -1.34198
ADSS adenylosuccinate synthase -1.34164
TCF12 transcription factor 12 -1.33913
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 -1.33835
KRT86 keratin 86, type II -1.33356
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 -1.33296
HNF1B HNF1 homeobox B -1.32346
B3GALNT2 beta-1,3-N-acetylgalactosaminyltransferase 2 -1.30634
DUSP9 dual specificity phosphatase 9 -1.29999
BACE2 beta-site APP-cleaving enzyme 2 -1.29625
NAV3 neuron navigator 3 -1.2827
PGF placental growth factor -1.2696
HIST1H1C histone cluster 1, H1c -1.26705
TCAF2 TRPM8 channel-associated factor 2 -1.26452
SETD7 SET domain containing (lysine methyltransferase) 7 -1.25877
HTR5BP 5-hydroxytryptamine (serotonin) receptor 5B, pseudogene -1.25827
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 -1.2538
ADD1 adducin 1 (alpha) -1.25035
PTHLH parathyroid hormone-like hormone -1.24978
MROH9 maestro heat-like repeat family member 9 -1.24921
MEDAG mesenteric estrogen-dependent adipogenesis -1.2458
GREB1L growth regulation by estrogen in breast cancer-like -1.23285
TRMT61B tRNA methyltransferase 61B -1.22512
VMA21 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) -1.21993
PHACTR4 phosphatase and actin regulator 4 -1.21798
NEURL1 neuralized E3 ubiquitin protein ligase 1 -1.21002
STIM2 stromal interaction molecule 2 -1.20299
LRRC38 leucine rich repeat containing 38 -1.19853
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -1.19423
SCRN3 secernin 3 -1.18375
MEG8 maternally expressed 8 (non-protein coding) -1.18014
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -1.17958
COL9A1 collagen, type IX, alpha 1 -1.17777
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K -1.17029
PAIP1 poly(A) binding protein interacting protein 1 -1.16898
TNC tenascin C -1.14885
PRCP prolylcarboxypeptidase (angiotensinase C) -1.14395
FBXO10 F-box protein 10 -1.13966
IGF1 insulin-like growth factor 1 (somatomedin C) -1.13226
USP3 ubiquitin specific peptidase 3 -1.1298
PRSS35 protease, serine, 35 -1.12676
WNT7A wingless-type MMTV integration site family, member 7A -1.12496
ENC1 ectodermal-neural cortex 1 (with BTB domain) -1.12481
EXD2 exonuclease 3'-5' domain containing 2 -1.12128
SWAP70 SWAP switching B-cell complex 70kDa subunit -1.12128
ANKRD10 ankyrin repeat domain 10 -1.11525
COL5A1 collagen, type V, alpha 1 -1.11282
IGSF3 immunoglobulin superfamily, member 3 -1.11069
COTL1 coactosin-like F-actin binding protein 1 -1.09784
AGER advanced glycosylation end product-specific receptor -1.08998
LIMA1 LIM domain and actin binding 1 -1.0867
USP20 ubiquitin specific peptidase 20 -1.06963
KDM5D lysine (K)-specific demethylase 5D -1.05564
ANKRD40 ankyrin repeat domain 40 -1.04956
LHX1 LIM homeobox 1 -1.03498
FGL1 fibrinogen-like 1 -1.03464
HAPLN1 hyaluronan and proteoglycan link protein 1 -1.02688
NPVF neuropeptide VF precursor -1.02614
DCAF10 DDB1 and CUL4 associated factor 10 -1.02286
THSD7A thrombospondin, type I, domain containing 7A -1.01433
LIMCH1 LIM and calponin homology domains 1 -1.01372
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 -1.00915
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -1.00645
PNMA3 paraneoplastic Ma antigen 3 -0.991851
MSX1 msh homeobox 1 -0.991142
CD200R1 CD200 receptor 1 -0.988958
AFTPH aftiphilin -0.985778
ACTL7A actin-like 7A -0.981595
FBLN2 fibulin 2 -0.976374
FAHD1 fumarylacetoacetate hydrolase domain containing 1 -0.975931
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.973661
ANKLE2 ankyrin repeat and LEM domain containing 2 -0.973535
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3 -0.972265
PAPPA pregnancy-associated plasma protein A, pappalysin 1 -0.965882
NKX1-2 NK1 homeobox 2 -0.962134
CREM cAMP responsive element modulator -0.96114
NCOA7 nuclear receptor coactivator 7 -0.956181
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 -0.94597
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.931294
SEC11C SEC11 homolog C (S. cerevisiae) -0.929689
RAB17 RAB17, member RAS oncogene family -0.928918
PJA1 praja ring finger 1, E3 ubiquitin protein ligase -0.926658
CENPA centromere protein A -0.925288
AUH AU RNA binding protein/enoyl-CoA hydratase -0.923863
CD8A CD8a molecule -0.918444
TMOD4 tropomodulin 4 (muscle) -0.908029
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -0.906529
DIXDC1 DIX domain containing 1 -0.906011
CD3E CD3e molecule, epsilon (CD3-TCR complex) -0.904345
MYO5A myosin VA (heavy chain 12, myoxin) -0.903315
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 -0.902915
NPR3 natriuretic peptide receptor 3 -0.900012
ACKR3 atypical chemokine receptor 3 -0.898074
SLC25A35 solute carrier family 25, member 35 -0.896706
ULBP1 UL16 binding protein 1 -0.88675
MT3 metallothionein 3 -0.879912
USP26 ubiquitin specific peptidase 26 -0.878313
RANBP17 RAN binding protein 17 -0.869791
CNOT10 CCR4-NOT transcription complex, subunit 10 -0.867727
HERPUD2 HERPUD family member 2 -0.858612
TTC9 tetratricopeptide repeat domain 9 -0.858612
SGIP1 SH3-domain GRB2-like (endophilin) interacting protein 1 -0.848362
JCHAIN joining chain of multimeric IgA and IgM -0.843311
OLAH oleoyl-ACP hydrolase -0.840772
PRAMEF8 PRAME family member 8 -0.838351
NFIC nuclear factor I/C (CCAAT-binding transcription factor) -0.833905
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit -0.830852
FAM91A1 family with sequence similarity 91, member A1 -0.830142
PLSCR1 phospholipid scramblase 1 -0.82475
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.822752
ACOT11 acyl-CoA thioesterase 11 -0.821309
TRIM33 tripartite motif containing 33 -0.820413
BAIAP2 BAI1-associated protein 2 -0.817632
DVL2 dishevelled segment polarity protein 2 -0.817434
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma -0.816643
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 -0.812562
GTPBP1 GTP binding protein 1 -0.805509
GNA14 guanine nucleotide binding protein (G protein), alpha 14 -0.793054
EFHB EF-hand domain family, member B -0.791266
NSF N-ethylmaleimide-sensitive factor -0.791266
ADA adenosine deaminase -0.791031
GRSF1 G-rich RNA sequence binding factor 1 -0.790422
GAPVD1 GTPase activating protein and VPS9 domains 1 -0.783951
TWIST1 twist family bHLH transcription factor 1 -0.781181
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 -0.780997
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa -0.77884
HSPA13 heat shock protein 70kDa family, member 13 -0.774559
NUP54 nucleoporin 54kDa -0.773426
SYT4 synaptotagmin IV -0.771212
MPZL2 myelin protein zero-like 2 -0.770897
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 -0.765037
WWP2 WW domain containing E3 ubiquitin protein ligase 2 -0.76026
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 -0.756928
DUSP16 dual specificity phosphatase 16 -0.756448
EEA1 early endosome antigen 1 -0.755011
MEF2A myocyte enhancer factor 2A -0.751416
OPRD1 opioid receptor, delta 1 -0.744522
APCDD1 adenomatosis polyposis coli down-regulated 1 -0.734485
BCL10 B-cell CLL/lymphoma 10 -0.734194
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.731712
SLC7A14 solute carrier family 7, member 14 -0.726873
SRPX2 sushi-repeat containing protein, X-linked 2 -0.725854
BTBD7 BTB (POZ) domain containing 7 -0.723663
TMEM72 transmembrane protein 72 -0.718635
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 -0.711459
GRIK1 glutamate receptor, ionotropic, kainate 1 -0.710949
RRM1 ribonucleotide reductase M1 -0.709891
PLEKHH2 pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 -0.704178
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) -0.700796
DOK7 docking protein 7 -0.692841
ZNF385B zinc finger protein 385B -0.692092
DBNDD2 dysbindin (dystrobrevin binding protein 1) domain containing 2 -0.687963
FKBP15 FK506 binding protein 15, 133kDa -0.686779
PHACTR1 phosphatase and actin regulator 1 -0.677338
REL v-rel avian reticuloendotheliosis viral oncogene homolog -0.675254
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) -0.674789
SP5 Sp5 transcription factor -0.674789
CIT citron rho-interacting serine/threonine kinase -0.672795
GRID2IP glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein -0.672085
KITLG KIT ligand -0.668588
ARF6 ADP-ribosylation factor 6 -0.664081
SMNDC1 survival motor neuron domain containing 1 -0.655715
THPO thrombopoietin -0.650597
NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5 -0.650523
KRT17 keratin 17, type I -0.649998
BPIFA1 BPI fold containing family A, member 1 -0.642335
CDON cell adhesion associated, oncogene regulated -0.636124
SPEN spen family transcriptional repressor -0.635909
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) -0.635624
TSPYL1 TSPY-like 1 -0.633694
ARF4 ADP-ribosylation factor 4 -0.632633
GIMAP5 GTPase, IMAP family member 5 -0.628344
TAGLN2 transgelin 2 -0.627924
CRTAC1 cartilage acidic protein 1 -0.627365
TRPM3 transient receptor potential cation channel, subfamily M, member 3 -0.62611
SEPT6 septin 6 -0.621841
TRIM21 tripartite motif containing 21 -0.621087
PANK4 pantothenate kinase 4 -0.620677
NRIP1 nuclear receptor interacting protein 1 -0.619721
TOB2 transducer of ERBB2, 2 -0.614995
SPTLC3 serine palmitoyltransferase, long chain base subunit 3 -0.614327
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 -0.612391
CD93 CD93 molecule -0.611194
TBC1D12 TBC1 domain family, member 12 -0.610596
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.610531
DSCAML1 Down syndrome cell adhesion molecule like 1 -0.610201
FST follistatin -0.60856
HOXB8 homeobox B8 -0.605684
ETNK1 ethanolamine kinase 1 -0.605553
CADM3 cell adhesion molecule 3 -0.602253
HMX1 H6 family homeobox 1 -0.600782
USP31 ubiquitin specific peptidase 31 -0.600716
RNF115 ring finger protein 115 -0.597593
ZNF148 zinc finger protein 148 -0.595639
WDR1 WD repeat domain 1 -0.595387
CEP120 centrosomal protein 120kDa -0.594322
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.592576
ALG10B ALG10B, alpha-1,2-glucosyltransferase -0.591517
RBM38 RNA binding motif protein 38 -0.589228
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits -0.587636
GSC goosecoid homeobox -0.587087
FABP6 fatty acid binding protein 6, ileal -0.583683
DACT3 dishevelled-binding antagonist of beta-catenin 3 -0.581283
TP63 tumor protein p63 -0.580626
OTP orthopedia homeobox -0.580268
PLEKHA4 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 -0.579733
SETD2 SET domain containing 2 -0.579674
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) -0.579318
SPPL3 signal peptide peptidase like 3 -0.579139
NFYA nuclear transcription factor Y, alpha -0.578841
N4BP1 NEDD4 binding protein 1 -0.577774
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) -0.574371
CCDC117 coiled-coil domain containing 117 -0.572394
ADAM1A ADAM metallopeptidase domain 1A (pseudogene) -0.571294
RCC2 regulator of chromosome condensation 2 -0.57008
AGFG1 ArfGAP with FG repeats 1 -0.569566
CFAP52 cilia and flagella associated protein 52 -0.568996
TMEM86A transmembrane protein 86A -0.565531
RBM4 RNA binding motif protein 4 -0.562833
LPCAT3 lysophosphatidylcholine acyltransferase 3 -0.562778
HDAC2 histone deacetylase 2 -0.560888
GAB3 GRB2-associated binding protein 3 -0.557685
PAQR8 progestin and adipoQ receptor family member VIII -0.555891
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 -0.555187
APMAP adipocyte plasma membrane associated protein -0.55432
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 -0.552108
PHF8 PHD finger protein 8 -0.550036
SCN2A sodium channel, voltage gated, type II alpha subunit -0.546814
MAPK11 mitogen-activated protein kinase 11 -0.545713
WAC WW domain containing adaptor with coiled-coil -0.544936
ZMYM3 zinc finger, MYM-type 3 -0.542094
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.54153
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 -0.538125
KIFC2 kinesin family member C2 -0.537268
DUSP19 dual specificity phosphatase 19 -0.535107
KIAA1462 KIAA1462 -0.534067
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.532932
TDGF1 teratocarcinoma-derived growth factor 1 -0.529207
MKRN1 makorin ring finger protein 1 -0.528532
LMO4 LIM domain only 4 -0.52781
GGT1 gamma-glutamyltransferase 1 -0.527666
LZTFL1 leucine zipper transcription factor-like 1 -0.527472
PI4KB phosphatidylinositol 4-kinase, catalytic, beta -0.526752
HAUS8 HAUS augmin-like complex, subunit 8 -0.525266
KLF3 Kruppel-like factor 3 (basic) -0.524263
KIF18A kinesin family member 18A -0.523839
CR1L complement component (3b/4b) receptor 1-like -0.519951
IFFO2 intermediate filament family orphan 2 -0.517049
NUP43 nucleoporin 43kDa -0.516682
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 -0.515861
FAR1 fatty acyl CoA reductase 1 -0.515178
USP45 ubiquitin specific peptidase 45 -0.515178
ASPDH aspartate dehydrogenase domain containing -0.513816
SOCS4 suppressor of cytokine signaling 4 -0.512923
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) -0.512432
HSPA4L heat shock 70kDa protein 4-like -0.511496
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) -0.509363
ELMSAN1 ELM2 and Myb/SANT-like domain containing 1 -0.507139
DRD4 dopamine receptor D4 -0.504625
ZNF689 zinc finger protein 689 -0.503389
CACNB1 calcium channel, voltage-dependent, beta 1 subunit -0.502837
LRRC23 leucine rich repeat containing 23 -0.502624
ACBD4 acyl-CoA binding domain containing 4 -0.501862
THBS1 thrombospondin 1 -0.498593
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B -0.496244
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) -0.495463
SBSPON somatomedin B and thrombospondin, type 1 domain containing -0.494773
SRD5A3 steroid 5 alpha-reductase 3 -0.494008
CDKN2AIP CDKN2A interacting protein -0.493848
TMCC2 transmembrane and coiled-coil domain family 2 -0.493848
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 -0.492882
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C -0.492602
RSF1 remodeling and spacing factor 1 -0.489897
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) -0.489897
C9ORF3 chromosome 9 open reading frame 3 -0.48931
PSME4 proteasome (prosome, macropain) activator subunit 4 -0.489192
AHRR aryl-hydrocarbon receptor repressor -0.489115
EME2 essential meiotic structure-specific endonuclease subunit 2 -0.48724
RPP40 ribonuclease P/MRP 40kDa subunit -0.486462
KLK3 kallikrein-related peptidase 3 -0.485395
ZNF292 zinc finger protein 292 -0.485395
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 -0.484936
STARD4 StAR-related lipid transfer (START) domain containing 4 -0.484936
TTC4 tetratricopeptide repeat domain 4 -0.483872
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha -0.483795
GPM6B glycoprotein M6B -0.48353
ANXA1 annexin A1 -0.482392
RNF215 ring finger protein 215 -0.482243
TPGS1 tubulin polyglutamylase complex subunit 1 -0.480092
CALD1 caldesmon 1 -0.479353
CREB3L1 cAMP responsive element binding protein 3-like 1 -0.47814
GRIPAP1 GRIP1 associated protein 1 -0.477742
SYT1 synaptotagmin I -0.475869
RBM8A RNA binding motif protein 8A -0.474187
PCDHB7 protocadherin beta 7 -0.473695
CLP1 cleavage and polyadenylation factor I subunit 1 -0.472156
ELFN1 extracellular leucine-rich repeat and fibronectin type III domain containing 1 -0.469869
FAM126B family with sequence similarity 126, member B -0.469496
IGHM immunoglobulin heavy constant mu -0.468679
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A -0.468612
ASIC2 acid sensing (proton gated) ion channel 2 -0.467493
HSCB HscB mitochondrial iron-sulfur cluster co-chaperone -0.465923
TTLL11 tubulin tyrosine ligase-like family member 11 -0.464341
BICD2 bicaudal D homolog 2 (Drosophila) -0.463913
TMEM106B transmembrane protein 106B -0.459548
SCN8A sodium channel, voltage gated, type VIII alpha subunit -0.457996
PAQR5 progestin and adipoQ receptor family member V -0.457903
CRYAA crystallin, alpha A -0.457841
MAT1A methionine adenosyltransferase I, alpha -0.457655
TTYH3 tweety family member 3 -0.457006
SPOP speckle-type POZ protein -0.456913
MIOX myo-inositol oxygenase -0.456358
SF3B2 splicing factor 3b, subunit 2, 145kDa -0.456083
TBKBP1 TBK1 binding protein 1 -0.455511
NSUN7 NOP2/Sun domain family, member 7 -0.45533
MED29 mediator complex subunit 29 -0.452786
COL3A1 collagen, type III, alpha 1 -0.450983
ALG3 ALG3, alpha-1,3- mannosyltransferase -0.450664
TTPA tocopherol (alpha) transfer protein -0.450605
RBM10 RNA binding motif protein 10 -0.45049
PLXNA3 plexin A3 -0.448693
ARHGAP12 Rho GTPase activating protein 12 -0.448103
LIN52 lin-52 DREAM MuvB core complex component -0.44771
NOL9 nucleolar protein 9 -0.447457
RGS16 regulator of G-protein signaling 16 -0.44743
C2CD4B C2 calcium-dependent domain containing 4B -0.447205
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1 -0.447148
FAM184B family with sequence similarity 184, member B -0.447121
LCOR ligand dependent nuclear receptor corepressor -0.445609
TRIM16 tripartite motif containing 16 -0.445554
SLC46A2 solute carrier family 46, member 2 -0.444848
CAST calpastatin -0.444632
SOX14 SRY (sex determining region Y)-box 14 -0.44455
TEK TEK tyrosine kinase, endothelial -0.444496
ABCC12 ATP-binding cassette, sub-family C (CFTR/MRP), member 12 -0.443128
LIME1 Lck interacting transmembrane adaptor 1 -0.442892
WDFY4 WDFY family member 4 -0.442367
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator -0.441109
PRX periaxin -0.44059
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme -0.440413
KCNIP3 Kv channel interacting protein 3, calsenilin -0.440235
EDNRB endothelin receptor type B -0.437664
KCMF1 potassium channel modulatory factor 1 -0.437541
NGDN neuroguidin, EIF4E binding protein -0.436734
ZNF608 zinc finger protein 608 -0.436173
FGF18 fibroblast growth factor 18 -0.062659
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -0.062478
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -0.062424
MANBAL mannosidase, beta A, lysosomal-like -0.061397
IVNS1ABP influenza virus NS1A binding protein -0.059771
ZRANB1 zinc finger, RAN-binding domain containing 1 -0.059188
EIF5 eukaryotic translation initiation factor 5 -0.058587
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1 -0.058493
CYC1 cytochrome c-1 -0.057837
RPS15A ribosomal protein S15a -0.057703
MED13L mediator complex subunit 13-like -0.057512
KIF1BP KIF1 binding protein -0.056691
SMIM20 small integral membrane protein 20 -0.056386
RPL26 ribosomal protein L26 -0.056044
COX6C cytochrome c oxidase subunit VIc -0.05537
ACOT13 acyl-CoA thioesterase 13 -0.055312
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 -0.05506
ABLIM1 actin binding LIM protein 1 -0.054925
LUC7L LUC7-like (S. cerevisiae) -0.054711
LPPR5 lipid phosphate phosphatase-related protein type 5 -0.053647
MRPS17 mitochondrial ribosomal protein S17 -0.052135
VEGFB vascular endothelial growth factor B -0.049674
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) -0.049416
MSRB3 methionine sulfoxide reductase B3 -0.048853
EHBP1 EH domain binding protein 1 -0.048793
DHX30 DEAH (Asp-Glu-Ala-His) box helicase 30 -0.048066
MYOM1 myomesin 1 -0.047863
FLRT2 fibronectin leucine rich transmembrane protein 2 -0.047762
SERF1A small EDRK-rich factor 1A (telomeric) -0.04744
RAD23A RAD23 homolog A (S. cerevisiae) -0.046977
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) -0.046321
PFDN5 prefoldin subunit 5 -0.046137
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -0.044973
AIF1L allograft inflammatory factor 1-like -0.044541
SEPW1 selenoprotein W, 1 -0.04363
RBPMS RNA binding protein with multiple splicing -0.043609
NDUFAF4 NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 -0.043113
ATOX1 antioxidant 1 copper chaperone -0.042762
MAST4 microtubule associated serine/threonine kinase family member 4 -0.041844
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) -0.041824
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -0.041719
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa -0.038098
PNISR PNN-interacting serine/arginine-rich protein -0.038098
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit -0.037332
MMAA methylmalonic aciduria (cobalamin deficiency) cblA type -0.037204
BOLA3 bolA family member 3 -0.036584
CCNL1 cyclin L1 -0.036285
EHD1 EH-domain containing 1 -0.035581
COX7C cytochrome c oxidase subunit VIIc -0.035367
PRDX4 peroxiredoxin 4 -0.035172
NDUFB5 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa -0.034956
ADCK3 aarF domain containing kinase 3 -0.034956
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 -0.033705
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit -0.032469
TJP2 tight junction protein 2 -0.032448
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -0.031881
COL4A1 collagen, type IV, alpha 1 -0.030467
SON SON DNA binding protein -0.030224
CFL2 cofilin 2 (muscle) -0.028775
MRPL47 mitochondrial ribosomal protein L47 -0.027784
SCYL1 SCY1-like 1 (S. cerevisiae) -0.025816
POFUT2 protein O-fucosyltransferase 2 -0.024901
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -0.023474
MSH2 mutS homolog 2 -0.02269
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 -0.021566
KIAA1524 KIAA1524 -0.020849
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 -0.02051
PHF7 PHD finger protein 7 -0.020397
STK3 serine/threonine kinase 3 -0.019177
PGAM2 phosphoglycerate mutase 2 (muscle) -0.018974
FILIP1 filamin A interacting protein 1 -0.018546
ZSCAN25 zinc finger and SCAN domain containing 25 -0.018274
VDAC2 voltage-dependent anion channel 2 -0.017842
PLAGL1 pleiomorphic adenoma gene-like 1 -0.016455
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa -0.016364
RASL11B RAS-like, family 11, member B -0.015978
DAP death-associated protein -0.015888
CDR2L cerebellar degeneration-related protein 2-like -0.015202
SEPT4 septin 4 -0.015088
EGFL7 EGF-like-domain, multiple 7 -0.01447
TENM3 teneurin transmembrane protein 3 -0.012271
HINT1 histidine triad nucleotide binding protein 1 -0.010642
UQCRH ubiquinol-cytochrome c reductase hinge protein -0.010434
SNURF SNRPN upstream reading frame -0.008911
MRPL42 mitochondrial ribosomal protein L42 -0.008726
TSTD2 thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 -0.006342
ACYP1 acylphosphatase 1, erythrocyte (common) type -0.006088
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit -0.005718
SLTM SAFB-like, transcription modulator -0.005602
TLK1 tousled-like kinase 1 -0.005508
IDH3B isocitrate dehydrogenase 3 (NAD+) beta -0.005159
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -0.003369
CORO7 coronin 7 -0.003369
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 -0.003322
COX4I1 cytochrome c oxidase subunit IV isoform 1 -0.002366
CUTA cutA divalent cation tolerance homolog (E. coli) -7.1E-4
ENO3 enolase 3 (beta, muscle) -3.13E-4
Funding