gef Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase. (Gene Ontology, GO_0005085)
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Genes

62 genes co-occuring with the biological term gef in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AKAP13 A kinase (PRKA) anchor protein 13
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ARF1 ADP-ribosylation factor 1
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
BCR breakpoint cluster region
CCDC88A coiled-coil domain containing 88A
CDC42 cell division cycle 42
CDH5 cadherin 5, type 2 (vascular endothelium)
CYTH2 cytohesin 2
DNMBP dynamin binding protein
DOCK6 dedicator of cytokinesis 6
DOCK7 dedicator of cytokinesis 7
ECT2 epithelial cell transforming 2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
ELMO1 engulfment and cell motility 1
EPHA8 EPH receptor A8
FGD4 FYVE, RhoGEF and PH domain containing 4
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
ICAM1 intercellular adhesion molecule 1
IQSEC3 IQ motif and Sec7 domain 3
ITSN1 intersectin 1 (SH3 domain protein)
KALRN kalirin, RhoGEF kinase
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
MAL mal, T-cell differentiation protein
MEF2A myocyte enhancer factor 2A
MKI67 marker of proliferation Ki-67
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PLXNB2 plexin B2
RAB18 RAB18, member RAS oncogene family
RAB31 RAB31, member RAS oncogene family
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RHOA ras homolog family member A
RHOC ras homolog family member C
RHOG ras homolog family member G
RHOJ ras homolog family member J
RIN3 Ras and Rab interactor 3
RINL Ras and Rab interactor-like
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC2A4RG SLC2A4 regulator
SOS1 son of sevenless homolog 1 (Drosophila)
TIAM1 T-cell lymphoma invasion and metastasis 1
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRAF2 TNF receptor-associated factor 2
TRIO trio Rho guanine nucleotide exchange factor
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor