| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the gefitinib-541 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACB | acetyl-CoA carboxylase beta |
| ACOT11 | acyl-CoA thioesterase 11 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF4 | activating transcription factor 4 |
| ATF5 | activating transcription factor 5 |
| AURKC | aurora kinase C |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic |
| C6 | complement component 6 |
| CAPN5 | calpain 5 |
| CARS | cysteinyl-tRNA synthetase |
| CCPG1 | cell cycle progression 1 |
| CCR8 | chemokine (C-C motif) receptor 8 |
| CD1A | CD1a molecule |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) |
| CDK19 | cyclin-dependent kinase 19 |
| CENPA | centromere protein A |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHN2 | chimerin 2 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CIDEC | cell death-inducing DFFA-like effector c |
| COX5B | cytochrome c oxidase subunit Vb |
| CTH | cystathionine gamma-lyase |
| CYB561 | cytochrome b561 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| EFNB3 | ephrin-B3 |
| EGR4 | early growth response 4 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) |
| EPOR | erythropoietin receptor |
| FAM129A | family with sequence similarity 129, member A |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FAM64A | family with sequence similarity 64, member A |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| GAST | gastrin |
| GIPC1 | GIPC PDZ domain containing family, member 1 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HTRA1 | HtrA serine peptidase 1 |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| JAG1 | jagged 1 |
| KAT6B | K(lysine) acetyltransferase 6B |
| KDM6B | lysine (K)-specific demethylase 6B |
| KIAA1045 | KIAA1045 |
| KIF21B | kinesin family member 21B |
| KLF3 | Kruppel-like factor 3 (basic) |
| LOC647070 | uncharacterized LOC647070 |
| LUZP1 | leucine zipper protein 1 |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| NIPAL2 | NIPA-like domain containing 2 |
| NXPH3 | neurexophilin 3 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| P2RX7 | purinergic receptor P2X, ligand gated ion channel, 7 |
| PCDH11Y | protocadherin 11 Y-linked |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PFDN4 | prefoldin subunit 4 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLCD1 | phospholipase C, delta 1 |
| PRDM11 | PR domain containing 11 |
| PRDM4 | PR domain containing 4 |
| PRDX2 | peroxiredoxin 2 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| PXN | paxillin |
| RAB4B | RAB4B, member RAS oncogene family |
| RHO | rhodopsin |
| RMND5B | required for meiotic nuclear division 5 homolog B (S. cerevisiae) |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| RPLP2 | ribosomal protein, large, P2 |
| RPS11 | ribosomal protein S11 |
| RPS28 | ribosomal protein S28 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLC38A1 | solute carrier family 38, member 1 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SRPK2 | SRSF protein kinase 2 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| STC2 | stanniocalcin 2 |
| STK19 | serine/threonine kinase 19 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TMEM134 | transmembrane protein 134 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TREML2 | triggering receptor expressed on myeloid cells-like 2 |
| TRIB3 | tribbles pseudokinase 3 |
| TSC22D3 | TSC22 domain family, member 3 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF518A | zinc finger protein 518A |
| ZNF589 | zinc finger protein 589 |
| ZNF816 | zinc finger protein 816 |
| Symbol | Name |
|---|---|
| ACTN4 | actinin, alpha 4 |
| AHCTF1 | AT hook containing transcription factor 1 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| ANKRD28 | ankyrin repeat domain 28 |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ATAD2 | ATPase family, AAA domain containing 2 |
| BCL7B | B-cell CLL/lymphoma 7B |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C11ORF48 | |
| C12ORF29 | chromosome 12 open reading frame 29 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C5ORF30 | chromosome 5 open reading frame 30 |
| CCDC94 | coiled-coil domain containing 94 |
| CD82 | CD82 molecule |
| CDC73 | cell division cycle 73 |
| CDK2AP1 | cyclin-dependent kinase 2 associated protein 1 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CPOX | coproporphyrinogen oxidase |
| CRTAP | cartilage associated protein |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CUTC | cutC copper transporter |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| CYBRD1 | cytochrome b reductase 1 |
| DENND4A | DENN/MADD domain containing 4A |
| DHRS7B | dehydrogenase/reductase (SDR family) member 7B |
| DPYD | dihydropyrimidine dehydrogenase |
| DUSP2 | dual specificity phosphatase 2 |
| ENDOG | endonuclease G |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GEMIN6 | gem (nuclear organelle) associated protein 6 |
| GLMN | glomulin, FKBP associated protein |
| GMPPB | GDP-mannose pyrophosphorylase B |
| GPR35 | G protein-coupled receptor 35 |
| GUCA1B | guanylate cyclase activator 1B (retina) |
| HDAC2 | histone deacetylase 2 |
| HSPA4L | heat shock 70kDa protein 4-like |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| IRF8 | interferon regulatory factor 8 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MED4 | mediator complex subunit 4 |
| MRPL33 | mitochondrial ribosomal protein L33 |
| MSMO1 | methylsterol monooxygenase 1 |
| MT1HL1 | metallothionein 1H-like 1 |
| NEFH | neurofilament, heavy polypeptide |
| NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) |
| NOL12 | nucleolar protein 12 |
| NUP93 | nucleoporin 93kDa |
| OBFC1 | oligonucleotide/oligosaccharide-binding fold containing 1 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| POR | P450 (cytochrome) oxidoreductase |
| PPOX | protoporphyrinogen oxidase |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNF111 | ring finger protein 111 |
| SDCCAG3 | serologically defined colon cancer antigen 3 |
| SEC24B | SEC24 family member B |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLAMF7 | SLAM family member 7 |
| SLBP | stem-loop binding protein |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC25A24 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| SRRD | SRR1 domain containing |
| STK26 | serine/threonine protein kinase 26 |
| STXBP3 | syntaxin binding protein 3 |
| SUSD6 | sushi domain containing 6 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 |
| TESK1 | testis-specific kinase 1 |
| TFB2M | transcription factor B2, mitochondrial |
| THOC1 | THO complex 1 |
| TMEM165 | transmembrane protein 165 |
| TMEM184C | transmembrane protein 184C |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| TTC4 | tetratricopeptide repeat domain 4 |
| UBAC1 | UBA domain containing 1 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| URGCP | upregulator of cell proliferation |
| USP39 | ubiquitin specific peptidase 39 |
| USP48 | ubiquitin specific peptidase 48 |
| UTP3 | UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) |
| WDR3 | WD repeat domain 3 |
| WDR46 | WD repeat domain 46 |
| WDR91 | WD repeat domain 91 |
| XPA | xeroderma pigmentosum, complementation group A |
| YTHDF2 | YTH N(6)-methyladenosine RNA binding protein 2 |
| ZNF124 | zinc finger protein 124 |
| ZNF180 | zinc finger protein 180 |
| ZNHIT6 | zinc finger, HIT-type containing 6 |
