geldanamycin-1008 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

199 genes differentially expressed following the geldanamycin-1008 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM19 ADAM metallopeptidase domain 19
ANGEL2 angel homolog 2 (Drosophila)
ASPH aspartate beta-hydroxylase
BAG2 BCL2-associated athanogene 2
BTN2A2 butyrophilin, subfamily 2, member A2
C18ORF25 chromosome 18 open reading frame 25
CA11 carbonic anhydrase XI
CCDC9 coiled-coil domain containing 9
CCNG2 cyclin G2
CD6 CD6 molecule
CENPO centromere protein O
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
COPA coatomer protein complex, subunit alpha
CRELD2 cysteine-rich with EGF-like domains 2
CSRP2 cysteine and glycine-rich protein 2
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DSPP dentin sialophosphoprotein
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
ERP44 endoplasmic reticulum protein 44
FGFR2 fibroblast growth factor receptor 2
FKBP14 FK506 binding protein 14, 22 kDa
FLJ11292
FNDC3A fibronectin type III domain containing 3A
FNDC3B fibronectin type III domain containing 3B
FXR1 fragile X mental retardation, autosomal homolog 1
GBP1 guanylate binding protein 1, interferon-inducible
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GLRX glutaredoxin (thioltransferase)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA13 heat shock protein 70kDa family, member 13
HSPA1A heat shock 70kDa protein 1A
HSPA4 heat shock 70kDa protein 4
HSPA4L heat shock 70kDa protein 4-like
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
HYOU1 hypoxia up-regulated 1
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KPNA5 karyopherin alpha 5 (importin alpha 6)
LMAN1 lectin, mannose-binding, 1
LPIN1 lipin 1
LPP LIM domain containing preferred translocation partner in lipoma
MANF mesencephalic astrocyte-derived neurotrophic factor
MAPK14 mitogen-activated protein kinase 14
MBNL2 muscleblind-like splicing regulator 2
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NAP1L2 nucleosome assembly protein 1-like 2
NIPAL2 NIPA-like domain containing 2
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PDIA4 protein disulfide isomerase family A, member 4
PJA2 praja ring finger 2, E3 ubiquitin protein ligase
PLA2G3 phospholipase A2, group III
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEKHS1 pleckstrin homology domain containing, family S member 1
POPDC3 popeye domain containing 3
PRSS16 protease, serine, 16 (thymus)
RAB6A RAB6A, member RAS oncogene family
RCAN1 regulator of calcineurin 1
RGS2 regulator of G-protein signaling 2
RNASE4 ribonuclease, RNase A family, 4
RPS3A ribosomal protein S3A
SDF2L1 stromal cell-derived factor 2-like 1
SEC24D SEC24 family member D
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNAP23 synaptosomal-associated protein, 23kDa
SP100 SP100 nuclear antigen
SRPR signal recognition particle receptor (docking protein)
SSR1 signal sequence receptor, alpha
STIP1 stress-induced phosphoprotein 1
TES testin LIM domain protein
TIAM1 T-cell lymphoma invasion and metastasis 1
TMED7 transmembrane emp24 protein transport domain containing 7
TMEM50B transmembrane protein 50B
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TSPYL2 TSPY-like 2
TXNIP thioredoxin interacting protein
ULBP2 UL16 binding protein 2
WDR1 WD repeat domain 1
WIPI1 WD repeat domain, phosphoinositide interacting 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZNF165 zinc finger protein 165
ZNF227 zinc finger protein 227
ZNF329 zinc finger protein 329

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ATF3 activating transcription factor 3
BACE1 beta-site APP-cleaving enzyme 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BIK BCL2-interacting killer (apoptosis-inducing)
C11ORF95 chromosome 11 open reading frame 95
C1ORF35 chromosome 1 open reading frame 35
C6ORF47 chromosome 6 open reading frame 47
C9ORF3 chromosome 9 open reading frame 3
CD3EAP CD3e molecule, epsilon associated protein
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLMN calmin (calponin-like, transmembrane)
COCH cochlin
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTNNBL1 catenin, beta like 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNMBP dynamin binding protein
DUSP8 dual specificity phosphatase 8
ECHDC3 enoyl CoA hydratase domain containing 3
EGR3 early growth response 3
ESRP2 epithelial splicing regulatory protein 2
FAM65A family with sequence similarity 65, member A
FHOD1 formin homology 2 domain containing 1
FJX1 four jointed box 1 (Drosophila)
FOXC1 forkhead box C1
FRAT2 frequently rearranged in advanced T-cell lymphomas 2
GFOD1 glucose-fructose oxidoreductase domain containing 1
GPR19 G protein-coupled receptor 19
GPRC5C G protein-coupled receptor, class C, group 5, member C
HOXC11 homeobox C11
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER2 immediate early response 2
INF2 inverted formin, FH2 and WH2 domain containing
INTS7 integrator complex subunit 7
IRX5 iroquois homeobox 5
KLF10 Kruppel-like factor 10
KLF11 Kruppel-like factor 11
KRT8P12 keratin 8 pseudogene 12
LIG4 ligase IV, DNA, ATP-dependent
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MCM3AP-AS1 MCM3AP antisense RNA 1
MED22 mediator complex subunit 22
MKNK1 MAP kinase interacting serine/threonine kinase 1
MNT MAX network transcriptional repressor
MT1HL1 metallothionein 1H-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NARFL nuclear prelamin A recognition factor-like
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PCF11 PCF11 cleavage and polyadenylation factor subunit
PGP phosphoglycolate phosphatase
PGPEP1 pyroglutamyl-peptidase I
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRKCD protein kinase C, delta
PTCD2 pentatricopeptide repeat domain 2
PTPRU protein tyrosine phosphatase, receptor type, U
PUS1 pseudouridylate synthase 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBL1 retinoblastoma-like 1
RBM38 RNA binding motif protein 38
RGS16 regulator of G-protein signaling 16
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIBC2 RIB43A domain with coiled-coils 2
SETD6 SET domain containing 6
SH2B2 SH2B adaptor protein 2
SIRT2 sirtuin 2
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SMAD7 SMAD family member 7
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SPATA2L spermatogenesis associated 2-like
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
TBCC tubulin folding cofactor C
TBL3 transducin (beta)-like 3
TDRD7 tudor domain containing 7
THOP1 thimet oligopeptidase 1
TMSB15B thymosin beta 15B
TRAPPC12 trafficking protein particle complex 12
TRIM45 tripartite motif containing 45
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSKU tsukushi, small leucine rich proteoglycan
TSPO translocator protein (18kDa)
TTLL12 tubulin tyrosine ligase-like family member 12
ZBED1 zinc finger, BED-type containing 1
ZBTB24 zinc finger and BTB domain containing 24
ZC3H12A zinc finger CCCH-type containing 12A
ZMAT5 zinc finger, matrin-type 5
ZNF239 zinc finger protein 239
ZNF580 zinc finger protein 580
ZXDC ZXD family zinc finger C