| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the geldanamycin-1169 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| AREG | amphiregulin |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| ATXN2L | ataxin 2-like |
| BAG3 | BCL2-associated athanogene 3 |
| BST2 | bone marrow stromal cell antigen 2 |
| C19ORF54 | chromosome 19 open reading frame 54 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CD47 | CD47 molecule |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 |
| CFP | complement factor properdin |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| COL4A2 | collagen, type IV, alpha 2 |
| CREM | cAMP responsive element modulator |
| CRY2 | cryptochrome circadian clock 2 |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
| CYTH1 | cytohesin 1 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| EFNB3 | ephrin-B3 |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FAM13A | family with sequence similarity 13, member A |
| FAS | Fas cell surface death receptor |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FKBP4 | FK506 binding protein 4, 59kDa |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FOXO1 | forkhead box O1 |
| GAMT | guanidinoacetate N-methyltransferase |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GK3P | glycerol kinase 3 pseudogene |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HTT | huntingtin |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IL33R | interleukin 33 receptor |
| IQCK | IQ motif containing K |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA1456 | KIAA1456 |
| KIF3C | kinesin family member 3C |
| KYNU | kynureninase |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LMF2 | lipase maturation factor 2 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MST1 | macrophage stimulating 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| NADK | NAD kinase |
| NOP16 | NOP16 nucleolar protein |
| NOX1 | NADPH oxidase 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NUCB1 | nucleobindin 1 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PHACTR2 | phosphatase and actin regulator 2 |
| PLCD1 | phospholipase C, delta 1 |
| PODNL1 | podocan-like 1 |
| PPID | peptidylprolyl isomerase D |
| PRMT2 | protein arginine methyltransferase 2 |
| RAB6A | RAB6A, member RAS oncogene family |
| RIPK2 | receptor-interacting serine-threonine kinase 2 |
| RUNX1 | runt-related transcription factor 1 |
| RXRA | retinoid X receptor, alpha |
| SAMD4A | sterile alpha motif domain containing 4A |
| SCAI | suppressor of cancer cell invasion |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SPAG5 | sperm associated antigen 5 |
| STAT5B | signal transducer and activator of transcription 5B |
| STIP1 | stress-induced phosphoprotein 1 |
| TADA2A | transcriptional adaptor 2A |
| TFG | TRK-fused gene |
| THBS1 | thrombospondin 1 |
| TPM1 | tropomyosin 1 (alpha) |
| TRA | T cell receptor alpha locus |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| ZNF493 | zinc finger protein 493 |
| Symbol | Name |
|---|---|
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| BBC3 | BCL2 binding component 3 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| BRIX1 | BRX1, biogenesis of ribosomes |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| CCDC86 | coiled-coil domain containing 86 |
| CCDC88C | coiled-coil domain containing 88C |
| CCNJ | cyclin J |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CEL | carboxyl ester lipase |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CORO7 | coronin 7 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) |
| DOLK | dolichol kinase |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
| EXOSC5 | exosome component 5 |
| FADS2 | fatty acid desaturase 2 |
| FKBP5 | FK506 binding protein 5 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HHLA3 | HERV-H LTR-associating 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KIAA0930 | KIAA0930 |
| KLHL26 | kelch-like family member 26 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MAPK12 | mitogen-activated protein kinase 12 |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| METTL1 | methyltransferase like 1 |
| METTL8 | methyltransferase like 8 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MTRF1 | mitochondrial translational release factor 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAK1IP1 | PAK1 interacting protein 1 |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLS1 | plastin 1 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PUS1 | pseudouridylate synthase 1 |
| PUS7 | pseudouridylate synthase 7 (putative) |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RHOH | ras homolog family member H |
| RNF122 | ring finger protein 122 |
| RPAP2 | RNA polymerase II associated protein 2 |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SCRIB | scribbled planar cell polarity protein |
| SDCCAG3 | serologically defined colon cancer antigen 3 |
| SETMAR | SET domain and mariner transposase fusion gene |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SREK1IP1 | SREK1-interacting protein 1 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SURF2 | surfeit 2 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TFB2M | transcription factor B2, mitochondrial |
| THAP4 | THAP domain containing 4 |
| THAP7 | THAP domain containing 7 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
| TTF2 | transcription termination factor, RNA polymerase II |
| TWISTNB | TWIST neighbor |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| USP6 | ubiquitin specific peptidase 6 |
| UTP3 | UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) |
| WDR3 | WD repeat domain 3 |
| WDR47 | WD repeat domain 47 |
| XPC | xeroderma pigmentosum, complementation group C |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| ZC2HC1A | zinc finger, C2HC-type containing 1A |
| ZNF140 | zinc finger protein 140 |
| ZNF573 | zinc finger protein 573 |