| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the geldanamycin-4452 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACE2 | angiotensin I converting enzyme 2 |
| ACTN2 | actinin, alpha 2 |
| ADCY7 | adenylate cyclase 7 |
| ADRA1D | adrenoceptor alpha 1D |
| ALPK3 | alpha-kinase 3 |
| ARHGAP28 | Rho GTPase activating protein 28 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| CBS | cystathionine-beta-synthase |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) |
| COPE | coatomer protein complex, subunit epsilon |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 |
| CRELD2 | cysteine-rich with EGF-like domains 2 |
| CRY2 | cryptochrome circadian clock 2 |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CTH | cystathionine gamma-lyase |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DUSP1 | dual specificity phosphatase 1 |
| EDN1 | endothelin 1 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| ERP44 | endoplasmic reticulum protein 44 |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FBN2 | fibrillin 2 |
| FLOT1 | flotillin 1 |
| FOXG1 | forkhead box G1 |
| GRAMD1B | GRAM domain containing 1B |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPB8 | heat shock 22kDa protein 8 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| HYOU1 | hypoxia up-regulated 1 |
| IFI44 | interferon-induced protein 44 |
| IL11 | interleukin 11 |
| IL7R | interleukin 7 receptor |
| LIPG | lipase, endothelial |
| MANF | mesencephalic astrocyte-derived neurotrophic factor |
| MAP1B | microtubule-associated protein 1B |
| MATN3 | matrilin 3 |
| MED25 | mediator complex subunit 25 |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NNMT | nicotinamide N-methyltransferase |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OXTR | oxytocin receptor |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PDZD2 | PDZ domain containing 2 |
| PHYHIP | phytanoyl-CoA 2-hydroxylase interacting protein |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase |
| POU6F1 | POU class 6 homeobox 1 |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| REEP2 | receptor accessory protein 2 |
| RFPL3 | ret finger protein-like 3 |
| RGCC | regulator of cell cycle |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEC24D | SEC24 family member D |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SETX | senataxin |
| SF1 | splicing factor 1 |
| SIRPG | signal-regulatory protein gamma |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| STK17B | serine/threonine kinase 17b |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TGFB2 | transforming growth factor, beta 2 |
| TMEM50B | transmembrane protein 50B |
| TREM2 | triggering receptor expressed on myeloid cells 2 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 |
| VWA5A | von Willebrand factor A domain containing 5A |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZFHX2 | zinc finger homeobox 2 |
| ZIC3 | Zic family member 3 |
| ZNF165 | zinc finger protein 165 |
| ZNF516 | zinc finger protein 516 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ADAM23 | ADAM metallopeptidase domain 23 |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BMP4 | bone morphogenetic protein 4 |
| BMPR1B | bone morphogenetic protein receptor, type IB |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CCNE1 | cyclin E1 |
| CCNE2 | cyclin E2 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDC25A | cell division cycle 25A |
| CDC7 | cell division cycle 7 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CENPT | centromere protein T |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) |
| CNTLN | centlein, centrosomal protein |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DDN | dendrin |
| DENND2D | DENN/MADD domain containing 2D |
| DEPDC5 | DEP domain containing 5 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| E2F8 | E2F transcription factor 8 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXO1 | exonuclease 1 |
| FAM111A | family with sequence similarity 111, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO31 | F-box protein 31 |
| FKBP5 | FK506 binding protein 5 |
| FRAT1 | frequently rearranged in advanced T-cell lymphomas 1 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HDAC11 | histone deacetylase 11 |
| HIST1H3B | histone cluster 1, H3b |
| HOXA4 | homeobox A4 |
| HOXA6 | homeobox A6 |
| HOXB2 | homeobox B2 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ITGA10 | integrin, alpha 10 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KIAA0319L | KIAA0319-like |
| KLF4 | Kruppel-like factor 4 (gut) |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MCC | mutated in colorectal cancers |
| MCM10 | minichromosome maintenance complex component 10 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTA2 | metastasis associated 1 family, member 2 |
| MXRA8 | matrix-remodelling associated 8 |
| MYH15 | myosin, heavy chain 15 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NDRG4 | NDRG family member 4 |
| NRTN | neurturin |
| OLFML2B | olfactomedin-like 2B |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| ORC1 | origin recognition complex, subunit 1 |
| OSMR | oncostatin M receptor |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 |
| PLA1A | phospholipase A1 member A |
| PLD2 | phospholipase D2 |
| PLXNB3 | plexin B3 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| POLL | polymerase (DNA directed), lambda |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| SCARA3 | scavenger receptor class A, member 3 |
| SH2B2 | SH2B adaptor protein 2 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| STON1 | stonin 1 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM206 | transmembrane protein 206 |
| TOM1 | target of myb1 (chicken) |
| TRIM9 | tripartite motif containing 9 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF574 | zinc finger protein 574 |
| ZNF652 | zinc finger protein 652 |
