| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the geldanamycin-593 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ADM2 | adrenomedullin 2 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ARHGAP5 | Rho GTPase activating protein 5 |
| ARMCX3 | armadillo repeat containing, X-linked 3 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ASPH | aspartate beta-hydroxylase |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked |
| BAG2 | BCL2-associated athanogene 2 |
| BRD2 | bromodomain containing 2 |
| BTN2A1 | butyrophilin, subfamily 2, member A1 |
| CAND1 | cullin-associated and neddylation-dissociated 1 |
| CCNG2 | cyclin G2 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| COG5 | component of oligomeric golgi complex 5 |
| CPD | carboxypeptidase D |
| CPT2 | carnitine palmitoyltransferase 2 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CYB561 | cytochrome b561 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 |
| EFNB3 | ephrin-B3 |
| ELMO2 | engulfment and cell motility 2 |
| ETV5 | ets variant 5 |
| FGFR2 | fibroblast growth factor receptor 2 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 |
| GLRX | glutaredoxin (thioltransferase) |
| GPR3 | G protein-coupled receptor 3 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HOXB5 | homeobox B5 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPE1 | heat shock 10kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HYOU1 | hypoxia up-regulated 1 |
| LDLR | low density lipoprotein receptor |
| LPAR1 | lysophosphatidic acid receptor 1 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 |
| LRRC61 | leucine rich repeat containing 61 |
| LZTFL1 | leucine zipper transcription factor-like 1 |
| MAML3 | mastermind-like 3 (Drosophila) |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MED14 | mediator complex subunit 14 |
| MIR22HG | MIR22 host gene |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NCKAP1 | NCK-associated protein 1 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| NUCB2 | nucleobindin 2 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 |
| NXT2 | nuclear transport factor 2-like export factor 2 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PCGF1 | polycomb group ring finger 1 |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRSS16 | protease, serine, 16 (thymus) |
| RBM5 | RNA binding motif protein 5 |
| RPS2 | ribosomal protein S2 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEC24D | SEC24 family member D |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERP1 | stress-associated endoplasmic reticulum protein 1 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SORT1 | sortilin 1 |
| SPN | sialophorin |
| SSR1 | signal sequence receptor, alpha |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| TMED7 | transmembrane emp24 protein transport domain containing 7 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRIM2 | tripartite motif containing 2 |
| TSPYL2 | TSPY-like 2 |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
| UFL1 | UFM1-specific ligase 1 |
| VCP | valosin containing protein |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF140 | zinc finger protein 140 |
| ZNF165 | zinc finger protein 165 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ATP13A2 | ATPase type 13A2 |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BBC3 | BCL2 binding component 3 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| CA11 | carbonic anhydrase XI |
| CCDC85C | coiled-coil domain containing 85C |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CENPO | centromere protein O |
| CETN1 | centrin, EF-hand protein, 1 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CORO2A | coronin, actin binding protein, 2A |
| CPN1 | carboxypeptidase N, polypeptide 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DUSP8 | dual specificity phosphatase 8 |
| ECE2 | endothelin converting enzyme 2 |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ERCC4 | excision repair cross-complementation group 4 |
| EVPL | envoplakin |
| EXOC3 | exocyst complex component 3 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GMIP | GEM interacting protein |
| GRPR | gastrin-releasing peptide receptor |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H4J | histone cluster 1, H4j |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| ILK | integrin-linked kinase |
| INE1 | inactivation escape 1 (non-protein coding) |
| JMJD4 | jumonji domain containing 4 |
| JUNB | jun B proto-oncogene |
| KRT8P12 | keratin 8 pseudogene 12 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MLYCD | malonyl-CoA decarboxylase |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NPPA | natriuretic peptide A |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| OCLN | occludin |
| OFD1 | oral-facial-digital syndrome 1 |
| PDE8B | phosphodiesterase 8B |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PPP2R2D | protein phosphatase 2, regulatory subunit B, delta |
| PRKCD | protein kinase C, delta |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RFC4 | replication factor C (activator 1) 4, 37kDa |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RRP1 | ribosomal RNA processing 1 |
| SCNN1G | sodium channel, non voltage gated 1 gamma subunit |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SMAD7 | SMAD family member 7 |
| SURF2 | surfeit 2 |
| SYTL2 | synaptotagmin-like 2 |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TCP10 | t-complex 10 |
| THAP11 | THAP domain containing 11 |
| TIPIN | TIMELESS interacting protein |
| TMEM186 | transmembrane protein 186 |
| TMEM51 | transmembrane protein 51 |
| TMEM8B | transmembrane protein 8B |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZBED2 | zinc finger, BED-type containing 2 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZNF219 | zinc finger protein 219 |
| ZNF250 | zinc finger protein 250 |
| ZNF32 | zinc finger protein 32 |
| ZNF74 | zinc finger protein 74 |
