| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the geldanamycin-611 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGR2 | anterior gradient 2 |
| AIM1L | absent in melanoma 1-like |
| APOOL | apolipoprotein O-like |
| ARHGAP5 | Rho GTPase activating protein 5 |
| ARMCX3 | armadillo repeat containing, X-linked 3 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATF2 | activating transcription factor 2 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CADM3 | cell adhesion molecule 3 |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CHN1 | chimerin 1 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CRMP1 | collapsin response mediator protein 1 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EPS8L1 | EPS8-like 1 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FNDC3B | fibronectin type III domain containing 3B |
| FXR2 | fragile X mental retardation, autosomal homolog 2 |
| GLRX | glutaredoxin (thioltransferase) |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GPATCH1 | G patch domain containing 1 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HLA-G | major histocompatibility complex, class I, G |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HYOU1 | hypoxia up-regulated 1 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IDUA | iduronidase, alpha-L- |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| KIF18A | kinesin family member 18A |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 |
| LRRC61 | leucine rich repeat containing 61 |
| MAP4 | microtubule-associated protein 4 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MIR22HG | MIR22 host gene |
| MVK | mevalonate kinase |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NUCB2 | nucleobindin 2 |
| OBSL1 | obscurin-like 1 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PADI1 | peptidyl arginine deiminase, type I |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| PHKG1 | phosphorylase kinase, gamma 1 (muscle) |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 |
| RCAN1 | regulator of calcineurin 1 |
| RGS2 | regulator of G-protein signaling 2 |
| RPS2 | ribosomal protein S2 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEC24A | SEC24 family member A |
| SEC24D | SEC24 family member D |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERP1 | stress-associated endoplasmic reticulum protein 1 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 |
| SIL1 | SIL1 nucleotide exchange factor |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| STK19 | serine/threonine kinase 19 |
| TES | testin LIM domain protein |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TH | tyrosine hydroxylase |
| TMED5 | transmembrane emp24 protein transport domain containing 5 |
| TMED7 | transmembrane emp24 protein transport domain containing 7 |
| TSPYL2 | TSPY-like 2 |
| TULP3 | tubby like protein 3 |
| WDR18 | WD repeat domain 18 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZNF165 | zinc finger protein 165 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| AEN | apoptosis enhancing nuclease |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| APEX2 | APEX nuclease (apurinic/apyrimidinic endonuclease) 2 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ARMC7 | armadillo repeat containing 7 |
| BYSL | bystin-like |
| C2CD5 | C2 calcium-dependent domain containing 5 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CA11 | carbonic anhydrase XI |
| CALHM2 | calcium homeostasis modulator 2 |
| CAMKV | CaM kinase-like vesicle-associated |
| CFAP74 | cilia and flagella associated protein 74 |
| CIC | capicua transcriptional repressor |
| CLSTN2 | calsyntenin 2 |
| COBL | cordon-bleu WH2 repeat protein |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CTPS1 | CTP synthase 1 |
| DUSP22 | dual specificity phosphatase 22 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| EPN3 | epsin 3 |
| ESRP2 | epithelial splicing regulatory protein 2 |
| EXOC3 | exocyst complex component 3 |
| FAM63A | family with sequence similarity 63, member A |
| FHOD1 | formin homology 2 domain containing 1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FUZ | fuzzy planar cell polarity protein |
| GABRQ | gamma-aminobutyric acid (GABA) A receptor, theta |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GMIP | GEM interacting protein |
| HELLS | helicase, lymphoid-specific |
| HIST1H4J | histone cluster 1, H4j |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| ILK | integrin-linked kinase |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KLF10 | Kruppel-like factor 10 |
| KLF15 | Kruppel-like factor 15 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL3 | kelch-like family member 3 |
| KLK8 | kallikrein-related peptidase 8 |
| LENEP | lens epithelial protein |
| LHX6 | LIM homeobox 6 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) |
| MLYCD | malonyl-CoA decarboxylase |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MST1R | macrophage stimulating 1 receptor |
| MTERF3 | mitochondrial transcription termination factor 3 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NIPAL2 | NIPA-like domain containing 2 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PDHA2 | pyruvate dehydrogenase (lipoamide) alpha 2 |
| PDZD7 | PDZ domain containing 7 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 |
| POMT1 | protein-O-mannosyltransferase 1 |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PRKCD | protein kinase C, delta |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| RAD54L | RAD54-like (S. cerevisiae) |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RBM14 | RNA binding motif protein 14 |
| RGS19 | regulator of G-protein signaling 19 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 |
| SYTL2 | synaptotagmin-like 2 |
| TAOK1 | TAO kinase 1 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TGM3 | transglutaminase 3 |
| THBS4 | thrombospondin 4 |
| TLN2 | talin 2 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRIM21 | tripartite motif containing 21 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| VIM | vimentin |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR13 | WD repeat domain 13 |
| ZCCHC6 | zinc finger, CCHC domain containing 6 |
| ZFP36 | ZFP36 ring finger protein |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF394 | zinc finger protein 394 |