| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the geldanamycin-6187 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACAN | aggrecan |
| ANXA6 | annexin A6 |
| AREG | amphiregulin |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 |
| BAG3 | BCL2-associated athanogene 3 |
| BAIAP2 | BAI1-associated protein 2 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CCNG2 | cyclin G2 |
| CDK19 | cyclin-dependent kinase 19 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEP135 | centrosomal protein 135kDa |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CIITA | class II, major histocompatibility complex, transactivator |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| COL4A2 | collagen, type IV, alpha 2 |
| CPEB3 | cytoplasmic polyadenylation element binding protein 3 |
| CRELD2 | cysteine-rich with EGF-like domains 2 |
| CREM | cAMP responsive element modulator |
| CRYZ | crystallin, zeta (quinone reductase) |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DUSP4 | dual specificity phosphatase 4 |
| EWSR1 | EWS RNA-binding protein 1 |
| FAM13A | family with sequence similarity 13, member A |
| FAS | Fas cell surface death receptor |
| FCAR | Fc fragment of IgA receptor |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FGFR1 | fibroblast growth factor receptor 1 |
| FKBP4 | FK506 binding protein 4, 59kDa |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| GPR65 | G protein-coupled receptor 65 |
| GRAMD1B | GRAM domain containing 1B |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase |
| HMOX1 | heme oxygenase 1 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA2 | heat shock 70kDa protein 2 |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HYOU1 | hypoxia up-regulated 1 |
| IL7R | interleukin 7 receptor |
| IQSEC1 | IQ motif and Sec7 domain 1 |
| KYNU | kynureninase |
| MAGT1 | magnesium transporter 1 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MSRB2 | methionine sulfoxide reductase B2 |
| MST1L | macrophage stimulating 1-like |
| MT1HL1 | metallothionein 1H-like 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| OPTN | optineurin |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PHTF1 | putative homeodomain transcription factor 1 |
| PIR | pirin (iron-binding nuclear protein) |
| PKN2 | protein kinase N2 |
| PPID | peptidylprolyl isomerase D |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| RGS2 | regulator of G-protein signaling 2 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RPL10L | ribosomal protein L10-like |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SEC24A | SEC24 family member A |
| SEC24D | SEC24 family member D |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SMIM14 | small integral membrane protein 14 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SPAG5 | sperm associated antigen 5 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) |
| THBS1 | thrombospondin 1 |
| THEMIS2 | thymocyte selection associated family member 2 |
| TMEM50B | transmembrane protein 50B |
| TPP1 | tripeptidyl peptidase I |
| UGDH | UDP-glucose 6-dehydrogenase |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| Symbol | Name |
|---|---|
| ADRB2 | adrenoceptor beta 2, surface |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| APOL6 | apolipoprotein L, 6 |
| ARID5A | AT rich interactive domain 5A (MRF1-like) |
| ARRB1 | arrestin, beta 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BYSL | bystin-like |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C5ORF28 | chromosome 5 open reading frame 28 |
| C5ORF30 | chromosome 5 open reading frame 30 |
| CCDC86 | coiled-coil domain containing 86 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CD14 | CD14 molecule |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDN | dendrin |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DHRS1 | dehydrogenase/reductase (SDR family) member 1 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ENDOG | endonuclease G |
| FAM127B | family with sequence similarity 127, member B |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FHOD1 | formin homology 2 domain containing 1 |
| FJX1 | four jointed box 1 (Drosophila) |
| FKBP5 | FK506 binding protein 5 |
| FOSL1 | FOS-like antigen 1 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 |
| GLCE | glucuronic acid epimerase |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IL24 | interleukin 24 |
| KIF21B | kinesin family member 21B |
| KLF11 | Kruppel-like factor 11 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MAK16 | MAK16 homolog (S. cerevisiae) |
| MAT2A | methionine adenosyltransferase II, alpha |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEC | plectin |
| PNO1 | partner of NOB1 homolog (S. cerevisiae) |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B |
| PQLC2 | PQ loop repeat containing 2 |
| PRAMEF11 | PRAME family member 11 |
| PRDM13 | PR domain containing 13 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PROCR | protein C receptor, endothelial |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PTRH2 | peptidyl-tRNA hydrolase 2 |
| PUS1 | pseudouridylate synthase 1 |
| PUS7 | pseudouridylate synthase 7 (putative) |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| REXO4 | REX4, RNA exonuclease 4 homolog (S. cerevisiae) |
| RFXAP | regulatory factor X-associated protein |
| RGS16 | regulator of G-protein signaling 16 |
| RGS19 | regulator of G-protein signaling 19 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RRP1 | ribosomal RNA processing 1 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SETD6 | SET domain containing 6 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SURF2 | surfeit 2 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TNF | tumor necrosis factor |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| UNG | uracil-DNA glycosylase |
| UPK3A | uroplakin 3A |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| XYLT2 | xylosyltransferase II |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZNF493 | zinc finger protein 493 |
