geldanamycin Gene Set

Dataset	GeneRIF Biological Term Annotations
Category	structural or functional annotations
Type	biological term
Description	A 19-membered macrocyle incorporating a benzoquinone ring and a lactam functionality. it is an ansamycin antibiotic and thus shows antimicrobial activity against many gram-positive and some gram-negative bacteria. (Chemical Entities of Biological Interest Ontology, CHEBI_5292)
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Genes

15 genes co-occuring with the biological term geldanamycin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol	Name
ADRBK1	adrenergic, beta, receptor kinase 1
CHEK1	checkpoint kinase 1
ERBB2	erb-b2 receptor tyrosine kinase 2
HRAS	Harvey rat sarcoma viral oncogene homolog
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90B1	heat shock protein 90kDa beta (Grp94), member 1
HSPD1	heat shock 60kDa protein 1 (chaperonin)
MAP3K11	mitogen-activated protein kinase kinase kinase 11
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
PCNA	proliferating cell nuclear antigen
RB1	retinoblastoma 1
RELB	v-rel avian reticuloendotheliosis viral oncogene homolog B
STUB1	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TNK2	tyrosine kinase, non-receptor, 2
TP53	tumor protein p53